Get Protein Right, Avoid Dying 6.4 Years Too Early

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Here are the links to the research papers referenced in the video:

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Video edited by Troy Young
Script by John Milliken

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All 15 study references are in the video's description.

DrBradStanfield
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What is confusing for me is that when you combine ENOUGH weight training WITH the high protein intake, you can live 6 years longer. But if you sit the whole day and don't do weight training, a lot of protein will just leave your body through the blatter. So, just eating protein does not help you to live longer. As with all those things, there are a lot of factors working together. Please start exercising if you are over 50!💪

ypmaklaes
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Mice are herbivores that don't eat meat in nature. Humans are omnivores that do eat meat. Why isn't this part of the consideration in mouse studies? Regardless of whether you can get protean from meat or plants, this difference between the test animals and us is going to have significant repercussions.

chrishowe
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Valter Longo did not only look at mice when making his recommendations to keep protein low in younger people, but to increase it in the elderly

robgibb
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You have a mistake here, it's not Leucine, rather it's Isoleucine: "restriction of isoleucine in adult mice extends lifespan in both males and females (Green et al., 2023), and in humans, blood levels of isoleucine, but not of leucine or valine, are positively associated with mortality (Deelen et al., 2019).Feb 7, 2023

veredk
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all these studies are like a ping pong game

aldousjove
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4:20 That 2018 meta analysis is out of date/not the best meta analysis currently out there on protein’s effect on muscle mass. Wolf coaching recently did a video on this. In 2020 there was a new meta analysis of randomised controlled trials that did a better analysis and included two dozen more studies that found benefits for muscle growth for substantially higher protein intakes, up to about 3.1g/kg of protein. The meta analysis is called “Dose-response relationship between protein intake and muscle mass intake: a systematic review and meta-analysis of randomised controlled trials”. The wolf coaching video is called “The fitness industry is not eating enough protein”.

meltedsnowman
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4:36 Someone who weighs 80 kg doesn’t have 80 kg of “lean body weight.”

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Human study: While *high amino acid diets were detrimental in middle-aged adults* (< 65 years), increased hazards of mortality were observed among older adults (≥ 65 years) with low amino acid intake.

Dietary amino acids intake and all-cause and cause-specific mortality: results from the Golestan Cohort Study

Not an RCT, but still concerning.

jackbuaer
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also, not to mention, Blue zones unfortunately have been debunked...

nuke
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Look, Leucin is one of the three aminoacids has been proven to extend life expectancy in mouse when restricted so precisely this maybe one of the reasons why vegetable protein shows better results in life expectancy than animal based.

phonixsolomon
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Brad this statistic 0.8g /kg is a one tail upper limit for the 97.5 % of the population. Based on nitrogen balance studies. The papers population average needs is around 0.62g/ kg. Or 50% of individuals require less than 0.62g / kg and so on.

barryinsabah
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Wouldn't consuming more leucine rich foods lead to chronic stimulation of mTOR? Would this still be a bad thing or is it no longer seen to be bad to be chronically stimulating mTOR?

haritanone
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Just got this fella worked out.. thanks for the help..

brucemaher
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Some people report protein in urine on high protein diets. We talking around 300grams a day. Such as athletes or strong men type of people. Is this normal or it is damaging the kidneys? Or it points to volume load

helios
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You say 1.6g per kg lean body weight. Lean body mass (LBM) is the weight of your body excluding fat. It includes the weight of your organs, skin, bones, body water, and muscle mass. This is different from total body weight, yet you say 130g protein for a person weighing 80kg. Does not compute.

briandrummond
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Humans have officially complicated the easiest and most important thing to us. Food. If I was back in my country I wouldn't be paying attention to these as much. I would just eat my organic yams, greens, fish etc. And walk ALOT. Keep it simple...

motivationalspeech
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The concept of "blue zones" has been called into question recently and i would love your take on it. IMO a topic worth its own video. The longevity numbers upon which the concept of "blue zones" is based may not be reliable..

mediawolf
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If animal products cause inflammation and inflammation beyond a point is ageing? (speculative) Does protein consumption correlate with inflammation? How does collagen correlate with lifespan?

knightmt
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I have recently increased my protein intake, and it as made noticeable gains in muscles. strength was at a plateau, I have for a while been consuming a collagen peptide from mixed sources grass fed cows and fish. shake for lunch, usually just 15 to 20 grams of protein, I now take 30 grams.

after workouts I have added Owyn protein shake this is plant based, 32grams of protein. lots of fiber, also different sources and kinds, Acacia fiber, Inulin, psyllium husk, and pectin. I just love the acacia, it has helped with a kidney issue I had/have with acacia I have no issues at all. also acacia does not give me gas or bloat (pectin and Inulin do, so I take less of these). the idea here is to feed my biome and healthy bacteria. (Forget probiotic, Prebiotics is where it's at).

I di take a host of supplements, TMG is in the mix. apiginine which I have added to my stack recently has helped with sleep.

agriperma