Low protein diet to delay aging?

There is lot of evidence supporting calorie restriction for lifespan extension, but is this due to generic calorie depletion or due to the reduction of specific macronutrients? Many studies have already looked into protein restriction to delay aging, we'll take a look at this and a recent study that looked into the reduction of specific amino acids, branched chain amino acids, and it turns out there are sex-dependent differences... Diet is complex and it seems also age-dependent and more work will be needed, but it seems that low protein may be promising to delay aging.

TIMESTAMPS:
Intro - 00:00
Protein restriction - 01:06
Branched chain amino acids - 05:29
Study results - 06:44
My thoughts - 11:40

REFERENCES:

[wholu]

You will never be afraid of chalk talk interviews..

[george]

As an active senior (70) that exercises everyday and mows his own lawn I need
more protein. Low protein might work for a young person like you, but not for my age bracket.
Sarcopenia is a danger for us.

[krisjaynav]

I’ve been pondering many of these concepts over the last 5 years. I was in the shower thinking of my menu for the next week as I was curious about reducing the amount of protein. So tonight I searched YouTube and found this. It was like every 90 seconds of this video many of my thoughts were addressed. Thank you for opening up the conversation. I appreciate ya, cheers

[fg_arnold]

I appreciate your willingness to keep independent of product sponsors. Definitely impacts how much credence I give to your presentations. Just subscribed. 👍

[galaxymetta]

For longevity, I place my bets on the mostly plant based diet in blue zone communities. Cheers.

[MarmaladeINFP]

It's the methionine to glycine ratio. Methionine comes from meat. And glycine comes from connective tissue. It's not necessarily a high-protein and menthione-excessive diet that is linked to decreased lifespan but a glycine-deficient diet. So, a diet that is animal-based, nose-to-tail, nutrient-dense, and well-balanced could be an effective strategy for optimal longevity, not to mention healthspan.

That is how I eat. Plus, I often do OMAD, intermittent fasting, and extended fasting; and hence regular autophagy. That is also how most hunter-gatherers have been eating for hundreds of thousands of years. Interestingly, all of the top most long-lived countries have the highest meat consumption in the world (e.g., Hong Kong); and yet I don't know that they do OMAD or fasting.

We want both periods of growth with upregulated mTOR and periods of repair with downregulated mTOR. There are multiple ways to achieve this end. But traditional societies tended to follow similar dietary patterns with periods of limited calories or none at all. Besides OMAD, feasting and fasting was particularly common among hunter-gatherers who often pride themselves on being able to fast.

benjamindavidsteele. wordpress. com/ 2019/09/17 /high-vs-low-protein/
benjamindavidsteele. wordpress. com/ 2019/07/09
benjamindavidsteele. wordpress. com/ 2019/10/01 /eat-beef-and-bacon/
benjamindavidsteele. wordpress. com/ 2019/05/28 /blue-zones-dietary-myth/
benjamindavidsteele. wordpress. com/ 2019/12/29
benjamindavidsteele. wordpress. com/ 2019/12/19
benjamindavidsteele. wordpress. com/ 2019/12/16

[pauljones]

I have minimised protein for years, and feel great

[slickJon]

It makes sense to say that these data are for regular people who don't exercise on a daily basis. People who lift weights or are doing weight resistance exercises need higher intake of protein. If they don't then the muscle starts eating itself. I wish researchers can stop providing data as if one size fits all.

[paul]

Yes, I'm also interested in practical strategies to continue building muscle while intermittent fasting, especially for someone who exercises every day. Thank you

[MT-sqjo]

Ok, so the question is, would you rather follow a low protein diet with the potential benefit of living longer but with the risk of sarcopenia (and increased risk of falling and breaking bones), or, would you rather eat a high protein diet to promote muscles building when you are young and able to prevent sarcopenia later in life (just like saving money for retirement) and risk dying early?

[randenrichards]

Just subscribed, your information is wonderful and your voice is soothing. However, being a weight lifter I don’t plan to change my protein regime, I have however been getting strict on the quality of the protein and incorporating hemp and egg protein in with my normal protein intake.

[diamond_s]

I think I heard methionine is the strongest amino that is detected by nutrient sensors. Lower methionine was seen to extend lifespan, and glycine supplementation which helps clear methionine was also seen as beneficial. But adequate protein is necessary to build muscle, 25% or higher protein diets were associated with 45% of stored excess calories going to muscle vs 95% going to fat in lower protein diets. More muscle easier weight loss. I think periodic short term fasting might provide the periods of low protein that put the body in a more protective state.

[timetravellist]

Can you give me examples of plant-based protein sources that are low in leucine and that doesn't activate mTOR? I can't find any.

[sroy]

Everyone says you are too fast, I like the way you are, (I fast forward your videos to save time) don't stop on the goodiness of the Sheekey science show!!

[williamthomasmoller]

So, what would be considered as high protein intake per day?

[johnely]

Thank you dear. Sometimes I need to play your videos a couple of times as your brain is so quick. Great work nevertheless. Johnny

[Chris-krgg]

Problem is other life issues are not being a pointed for here, for instance stress, sleep, water source and exercise levels and smoking and drug abuse etc.

[davidwelburn]

Although I find your videos really difficult to follow (because you whizz through the content way too fast for me), this was a really intersting one. As someone who has lifted weights pretty much all my life, I have always followed a high protein diet. Maybe that was not the best thing to do, but now I'm approaching 60, I may need to keep it fairly high, but might need to think about the actual composition of the protein types. Thanks for alerting me to this.

[TheIgnacio]

Does protein 'quality' apply to supplements and/or food? Most plant based protein supps are incomplete and the best are adjusted to match the amino distribution of animal protein.

[andrewnorris]

I'm not sure why Rhonda Patrick and Brad Stanfield are focusing on high protein and big muscles so much now. I just saw Rhonda say in a video that you need to get muscles built up as if you lose them when bed ridden you can never get them back. Could be something in it after 65, but best way would be via exercise. Also I reckon if you save the things like creatine and protein powders until you do get bed ridden when older - they will have more chance of working to help rebuild than if you have been taking them for years and the body got used to them.