How Inflammation Really Works | Institute of Human Anatomy

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In this video, Jonathan from the Institute of Human Anatomy explains the fascinating science of inflammation. Discover what defines inflammation, how your body responds to injuries and infections, as well as the incredible process that unfolds at the cellular level. From tissue macrophages to neutrophils and monocytes, learn how your immune system fights inflammation—and what you can do to speed up recovery!

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0:00 - 0:54 Intro
0:55 What Exactly is Inflammation?
2:50 How Your Body Attacks Infections in Minutes
8:29 What You Need to Know About Inflammation
10:48 Your Body’s War vs Inflammation
14:58 How You Can Help Your Body Fight Inflammation

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Common Questions Answered in This Video
What is inflammation, and how does it work?
What are the differences between acute and chronic inflammation?
How do tissue macrophages and neutrophils respond to an injury?
What is margination, and how does it relate to inflammation?
How do monocytes contribute to resolving inflammation?
Can lifestyle changes help reduce inflammation naturally?
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#Inflammation #ImmuneResponse #ReduceInflammation #TissueRepair #healthtips

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[lvair]

They should give you an award for releasing videos like this for free

[UnluckyGunner]

The sign of a good teacher is someone who can take a complex subject and explain it to a 3 year old, good job and thank you as always!

[tinytron]

my mom died two days ago, and one thing the doctors always brought up was my moms brain being inflamed by her cancer. i wish we understood health more than what i thought we already knew. stay safe everyone and get your doctor checkups every once in a while 💗

[weston.weston]

Jonathan, you're cranking out the content solo these days, we're glad you're here, friend! Thank you for aiding our A&P knowledge!

[SaeedehLordan]

I am a master student in toxicology and honestly I have learned so much here. You explain topics 100 times better than any lecturer. The Best!

[paulkoza]

The human body is a chemical factory. I woud like to see a series on chronic inflamation. This is a condition that many of us suffer from.

[DrSainteDAc]

For decades, I've been explaining pathophysiology to my patients. I just wish I were half as good at it as you! My goodness, you are adept. Thanks for you and your skills.

[williemienie]

Your intelligence is mind blowing. I appreciate your work immensely.

[cinnamongirl]

Superb breakdown. So glad you added all the chronic inflammatory conditions. People need to realize that healing requires inflammation, but chronic inflammation is the root cause of all the ailments you mentioned, and then some.

[ptero]

I love the humor sprinkled in with all the great and fascinating technical information.

[Janieblueyes]

Here is a fun fact, I have been on a GLP-1 agonist for my T2 diabetes. I had chronic bowel inflammation and very high inflammation markers, since being on semaglutide :50 weekly, my inflammation markers have reduced significantly. My colitis is almost non existent. BSL very stable @ 5. No longer metabolically blown out . Normal iron levels . Amazing

[AngMarie]

I have no idea how your video ended up in my YouTube feed given I listen to true crime podcasts and current court cases all day long yet I am so happy it did! You are incredibly knowledgeable as well as entertaining therefore I could not stop watching this video! Thank You! You are much appreciated 😊

[segurahh]

00:00 Introduction to inflammation

• Inflammation is the healing process, and not always a negative process.
• Inflammation can become chronic under certain conditions.
• Video discusses how inflammation works and what signals the body uses for healing.

00:54 Signs of inflammation

• Inflammation is manifested by redness, edema, heat, pain and loss of function.
• These signs have a certain goal and can be explained by the stages of inflammation.

01:36 Start of inflammation

• Inflammation begins with damage to tissues and cells.
• Damage can be caused by injury or pathogenic microorganisms.
• Damaged tissue distinguishes substances called cytokines, which initiate an inflammatory reaction.

02:33 Role of tissue macrophages

• Fabric macrophages are the first to respond to damage.
• They participate in the process of phagocytosis, absorbing dead tissues and pathogenic microorganisms.
• These macrophages are important, but they are not enough for severe injuries and infections.

03:56 attracting neutrophils

• Neutrophils begin to penetrate into the inflamed area an hour after the start of inflammation.
• Cytokines attract neutrophils to the place of damage through chemotaxis.
• Neutrophils stick to the wall of the capillary, which allows them to penetrate the focus of inflammation.

05:37 The process "Rolly-Shkiv"

• Neutrophils pass through the cracks between endothelial cells.
• This process is called marginalization and range.
• Neutrophils help tissue macrophages protect and cleanse damaged tissues.

07:08 Reducing of skin inflammation

• Illumina LED face mask helps reduce skin inflammation.
• The mask is equipped with 360 LEDs and provides therapy with red, infrared and blue light.
• The device helps with acne, sunburn and improves blood flow and collagen production.

08:33 Conclusion

• Inflammation delivers white blood cells to the place of damage for healing.
• Symptoms of inflammation, such as redness, heat and swelling, are explained by the expansion of capillaries and a leakage of liquid.
• The difference between inflammation caused by injury and pathogen is additional damage during injury.

09:58 A break in capillaries and swelling

• The breakdown of capillaries can lead to edema and bruises.
• White blood cells play a key role in the delivery to the place of damage.
• Monocytes are released from the blood and penetrate into inflamed tissue.

10:57 Monocytes and macrophages

• Monocytes turn into macrophages, destroying bacteria and viruses.
• Macrophages are more powerful phagocytes than neutrophils.
• Macrophages can survive and function for months after completing their task.

12:40 The role of neutrophils

• Neutrophils are important in the early stages of inflammation.
• In the blood, it circulates more neutrophils than monocytes.
• Neutrophils help to keep the defense before the arrival of monocytes.

13:29 Lymphatic system

• Lymphatic capillaries are more permeable than bloody.
• They help to remove excess fluid and bacteria.
• Lymph nodes contain more white blood cells for filtering.

14:41 Protocol of Rice

• Rest, ice, compression and rise accelerate the healing process.
• Compression and raising help lymphatic drainage.
• Movement stimulates blood flow and promotes healing.

16:34 Restoration and inflammation

• Inflammation stimulates the growth of new capillaries and cells.
• The body is restored due to the release of growth factors.
• Inflammation can become chronic with improper management.

17:27 Conclusion

• Inflammation is an important process in proper work.

[carolpiirto]

I love how you cover complicated topics to non medical people in simpler terms. Love it!!! THANKS!

[riverbender]

Fascinating! Thanks for explaining that inflammation (like fever) is not completely a "bad guy".

[queenseabee]

I know you can only squeeze so much info into these videos and i appreciate it. I have lupus that causes constant inflammation. Do you guys have a video on that?

[theorgelmeisterakathesoapm]

You guys always do such a great job explaining things the average non medical person would not understand. I'm always happy to see when you've released another video. Thanks so much for the content.

[juliemarkham]

Awesome explanation! Our bodies are amazing. Thanks.

[TellyPower]

You should explain complex regional pain syndrome or rsd. I have this and flare ups I get all these symptoms frequently, inflammation, hot and or cold to the touch, change of colour, constant pain and sometimes loss of movement in bad pain flares. I know a lot about what I have but would be cool to see you break it down😊

[runnn]

Well done! The issue is that each of us is so very different, and precisely why one person can smoke their entire life yet never develop malignant lung cancer while another person who is briefly exposed to second hand smoke develops malignant lung cancer. Once science determines what is harmful/helpful for us individually (testing), then we’ll see advanced lifespans and dramatic improvement in quality of life.