​8 Best Supplements to Build Muscle (2024)

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These are the 8 best supplements to take to build muscle fast. Learn which supplements are for gaining muscle mass and which ones are a waste of money. If you're a skinny hard gainer your efforts should be mostly focused on your diet and workout plan. But supplements can definitely help, watch this video to learn how to take them for building muscle.

You can just sit around on a couch, take certain supplements and you'll build massive amounts of muscle. Obviously, I'm kidding but that's what most supplement companies want you to believe. Unfortunately, even with all the modern advancements in nutrition science your progress is still mostly tied to your overall diet and workout plan. However, supplements can give you quite an edge, and that edge can truly help you build muscle faster, increase strength, and break through stagnation and stubborn plateaus. So today I want to go over 8 supplements that can help force muscle growth even when you're feeling totally stuck. 
First I want to start with carnosine which is actually a combination of beta-alanine and histidine. Both beta-alanine and histidine are abundantly present in many tissues throughout the body, including the brain, gut, heart, and muscles.

One of the key roles of carnosine in muscle physiology is its ability to combat muscle fatigue by reducing the buildup of acidic substances within your muscles. These acidic substances accumulate as you work out, and a lot of that burn as well as fatigue that sets in as you're lifting weights for reps is caused by these acidic by-products. By lowering this acidity, both beta-alanine and l histidine can improve endurance helping you squeeze out one or two additional reps before failure which can make a huge difference in your muscle-building progress since building muscle is predominately tied to progressive overload or simply put increasing reps and weight load over time. On top of that, carnosine is actually an antioxidant, helping to protect muscle cells from oxidative stress and damage. It also plays a role in regulating calcium levels within muscle cells, which is very important for muscle contractions.    

Carnosine is actually a common addition already found in many pre-workout supplements, and pre-workouts are actually the next supplement that can make a big difference when it comes to building muscle. One of the ways that pre-workouts provide this benefit is by increasing your energy and focus. This is because most of them contain stimulants like caffeine for example. Having more focus and energy can help you perform more intense workouts, lift heavier weights, and ultimately gain strength and muscle. Another benefit of pre-workouts is that they commonly contain Nitric oxide boosters like citrulline and L-Arginine.

These amino acids promote vasodilation, or in other words the expansion of your blood vessels which helps increase blood flow to your muscles. This leads to what's commonly referred to as "the pump," which can improve nutrient delivery and the removal of waste products, potentially supporting muscle growth. (8) One thing to keep in mind, is that the more that you take pre-workouts the more reliant you'll be on them, and you'll probably feel less and less of an energy boost. Like any other stimulant, your body will develop a tolerance, so I recommend not using pre-workouts every day, and instead only use it on days that you're lifting heavy and pushing yourself to grow. 

Now let's move on to one of the most widely studied and proven supplements for building muscle...creatine. We know that creatine enhances exercise performance by increasing your body's stores of phosphocreatine, which is a quick-acting energy source used during short bursts of high-intensity activity, such as weightlifting. (9) This allows you to lift heavier weights and perform more reps which, over time, should lead to greater muscle stimulation and growth. Creatine also increases the retention of water within muscle cells, leading to increased cell volume and improved hydration.

Not only does this make your muscles appear full and larger, but this cellular swelling can trigger certain anabolic pathways, that lead to muscle growth. (10) At the same time creatine helps stimulate muscle protein synthesis while reducing myostatin levels which is a protein that interferes with muscle growth. (11) Your body is constantly breaking down muscle tissue when you work out and in general throughout the day as you move around. Since building muscle is highly dependent on increasing protein synthesis, while reducing muscle protein breakdown creatine can be very helpful. As if that not enough reason to try creatine, it also is associated with faster muscle recovery by reducing inflammation allowing for more frequent intense training sessions. To get started you can simply take 5 grams of creatine per day after your workouts...
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References:

1. Wilson, J. M., et al. The effects of 12 weeks of free acid supplementation on muscle mass, strength, and power in resistance-trained individuals: a randomized, double-blind, placebo-controlled study. European Journal of Applied Physiology, 113(3), 655-665.

2. Nissen, S., et al. Effect of leucine metabolite β-hydroxy-β-methylbutyrate on muscle metabolism during resistance-exercise training. Journal of Applied Physiology, 81(5), 2095-2104.

3. Panton, L. B., et al. The effects of HMB on muscle strength and body composition in resistance trained individuals. Journal of Exercise Physiology Online, 3(3), 4-9.

4. Kreider, R. B., et al. Effects of calcium β‐hydroxy‐β‐methylbutyrate (HMB) supplementation during resistance‐training on markers of catabolism, body composition and strength. International Journal of Sports Medicine, 20(06), 415-424.

5. Dutka, T. L., et al. Carnosine inhibits [Ca2+]i and contractility in mouse fast-twitch muscle. Journal of Physiology, 586(2), 447-458.

6. Rashid, I., et al. Carnosine: a protective and anti-aging peptide. Protein and Peptide Letters, 24(2), 154-160.

7. Evidence of pre-workouts enhancing energy and focus- Astorino, T. A., & Roberson, D. W. Efficacy of acute caffeine ingestion for short-term high-intensity exercise performance: a systematic review. The Journal of Strength & Conditioning Research, 24(1), 257-265.
- Goldstein, E. R., et al. International society of sports nutrition position stand: caffeine and performance. Journal of the International Society of Sports Nutrition, 7(1), 5.

8. Pérez-Guisado, J., & Jakeman, P. M. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. The Journal of Strength & Conditioning Research, 24(5), 1215-1222.

9. Creatines ability to boost exercise performance:- Buford, T. W., et al. International Society of Sports Nutrition position stand: creatine supplementation and exercise. Journal of the International Society of Sports Nutrition, 4(1), 6.
- Kreider, R. B. Effects of creatine supplementation on performance and training adaptations. Molecular and Cellular Biochemistry, 244(1-2), 89-94.

10. Volek, J. S., & Rawson, E. S. Scientific basis and practical aspects of creatine supplementation for athletes. Nutrition, 20(7-8), 609-614.

11. Willoughby, D. S., & Rosene, J. Effects of oral creatine and resistance training on myosin heavy chain expression. Medicine and Science in Sports and Exercise, 33(10), 1674-1681.

12. Whey protein Tang, J. E., et al. Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men. Journal of Applied Physiology, 107(3), 987-992.
Tang, J. E., et al. Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men. Applied Physiology, Nutrition, and Metabolism, 33(6), 1124-1131.

13. Tipton, K. D., et al. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. American Journal of Physiology-Endocrinology and Metabolism, 288(6), E1096-E1102.

14. Girgis, C. M., & Clifton-Bligh, R. J. Skeletal muscle and the effects of vitamin D. Hormone and Metabolic Research, 45(04), 289-293.

15. Tomlinson, P. B., et al. Effects of vitamin D supplementation on upper and lower body muscle strength levels in healthy individuals. A systematic review with meta-analysis. The Journal of Science and Medicine in Sport, 18(5), 575-580.

16.  Smith, G. I., et al. Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial. The American Journal of Clinical Nutrition, 93(2), 402-412.

17. DiLorenzo, F. M., et al. Beneficial effects of long-chain omega-3 fatty acids in neuromuscular diseases. Neuromolecular Medicine, 16(1), 42-51.

GravityTransformation
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1. Carnosine
2. Pre Workouts
3. Creatine
4. Whey Protein
5. Weight Gainer Shake
6. Vitamin D
7. Omega 3
8. HMB

OG_Tony
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1:50 Preworkout
2:45 Creatine
4:10 Whey protein
6:00 Vitamin D
6:50 Omega 3
10:10 BCAA; Glutamine
10:30 DHEA

alphabeta
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You make some of the best videos out there, simple and understandable for people who get confused from disinformation👌
Thank you man, keep on the great job 👏

herculess
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You should release a video of what you take and how/when to use them. I'm curious to see goes well while stacking

vincemontanez
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To all my brothers out there, keep fighting the good fight.

shaunguffey
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hello bro big fan of yours from india, your diet videos helped me alot in my body.

Anonymous-jetc
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Thank you for this high amount of knowledge ❤️🙏

erfantv
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LOVED this!!!! I’ll watch this several times until I completely understand the content. 👍🏾👍🏾💪🏾

CW-ougu
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Excelent video. Thanks for this useful info.

miguelangelescalantegonzal
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Thank you for mentioning the waste-of-money supplements. I have the feeling one could make an entire video about that.

VTVT
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Which is made that won't cause cancer?

nandecomics
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Hey I have been using pure choice and I have no problem. Check the ingredients. Maybe the brand you used had too many fillers.😢

tommyp
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bro please keep posting i love your vids

sufiannavi
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I know some don't agree with me, but it was very true for me/personally. Creatine caused my hair to thin. I first took 5g a day (every day for six months straight). I started noticing some thinning. I stopped taking it for two months. The hair started thickening again. So, I started taking 3g instead. After two months, i noticed it again (so did my wife). So, I kept it at 3g and started taking Rogaine. It stopped the thinning, but did not make it thick. So, I stopped creatine completely and it went back to normal. I might try taking Rogaine with 3g of creatine, while it is thick again, but I don't know if it worth it.

sirjonsmithiii
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Thanks a lot for the information you providing us, could you please mention some good supplements for biceps vines or for all vascularity.

Thanks

sadatnajim
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whey protein is the best. unless you are counting macros and able to eat until you feel sick, protein powder will help massively.

Othusdragonreviews
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Very good and informative video. Well done

nikos
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1. Testosterone injection
2. Trenbolan Acetate injection
3. Dianabolan oral pill/ Anavar oral pill (never together)
4. Chocolate Milk

FacetiousEnigma
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Just because you might be able to endure longer or more frequent exercise sessions, reps or sets, doesn't mean that you will progress faster / farther, or? The traditional view is that structural and chemical strain due to exercise, will push your body to better endure those types of efforts. If you tank after, say, 8 or 10 reps, 3 or 4 sets, both lead to similar improvements beyond that particular session?

jarinorvanto