Fallout 4: The Complete Guide to Vault 81

0:30 How to gain entry into Vault 81
0:55 meet Austin Engil and agree to go on his tour
1:20 (Here kitty kitty) agree to help find Ashes the cat
1:48 return to Erin Combes to collect a Fusion Core for finding Ashes
1:52 talk to Katy to start the quest Short Stories
2:05 Go to the classroom during daytime hours to talk to the children about deathclaws
2:30 Don't forget to go to Horatio's barber shop to get a copy of Taboo Tattoos!
2:35 Talk to Dr Penske to taste test a new strain of MutFruit
2:55 agree to donate (or get paid for) a blood sample to Dr Forsythe's medical research
3:12 Leave Vault 81 for at least 24 hours... and go get yourself some serious firepower. The Higher the ROF the better.
4:20 IMPORTANT Dismiss you companions before returning to Vault 81
4:40 Head down to Dr Forsythe's lab to learn that Austin has came down with a serious illness
5:00 follow Bobby De Luca to the entrace to the real Vault 81

START QUICKSAVING/SAVE SCUMMING LIKE CRAZY AS SOON AS YOU ENTER SECRET VAULT 81

6:22 take out the turrets and hack the (novice) terminal to get a Legenday Protectron Guardian on your side
7:00 hack an expert terminal to get to the final room of the vault
OR
Very carefully fight your way through a large pack of infected mole rats lead by a brood mother to get the passcode at the end of the hallway.
7:58 enter the final room of Vault 81 and talk to Curie, the french robot. Tell her you're with Vault Tech and she'll hand over the cure no problem.
8:23 Return to Dr Forsythe to give him the cure for Austin (you should have to keep it for yourself if you were careful and didn't bring any companions along)
8:50 recieve a boatload of rewards including your own room in Vault 81 and a syringer rifle.
9:10 Talk to Curie to unlock her as a companion
9:27 head down to the reactor room and Talk to Tina De Luca about Bobby's drug habits
9:50 Agree to help and you will start the quset, "Dependency"
9:55 go to Bobby De Luca and pass a medium speech check to get him to kick his habits.
10:07 return to Tina De Luca and she'll give you as minor XP reward and you'll complete Dependency. Passing a high level speech check will allow you to recruit her to one of your settlements

Licensed under Creative Commons: By Attribution 3.0

[cocacola]

Way to go in without needing a big speech requirement, but you will need 3 fusion cores, but you won't lose em: Say "Yeah I'll give you the fusion cores." And then once you're in the vault the Overseer will ask for the Fusion Cores. Just look away and drop the fusion cores, then go back and look at her. She will give you 100 caps and you don't lose any cores, and you can pick them back up!

[pyroblaze]

When I saw the entrance I thought it was a destroyed vault. When I entered I didn’t expect it to be fully functional

[Mrsaladization]

I was walking around just talking to people and no one would give me any quest. Thank u for this vid

[MrClinker]

Don't activate the protectron in the vault. You can get the mole rat disease if it is attacked. The protectron acts as a companion

[paintballfan]

help Bobby? and lose my best customer? no way. (I'm a chem dealer)

[instinct]

Has anyone noticed that when you press B while doing the tour with Austin, your character makes side groans, sighs, and comments? It's hilarious!

[melkerweden]

Use the cryolator form vault 111 it slows the mole rats down and kills them

[cyann]

Quick tip: if you don't have a high hack skill bring nick valentine with you and command him to hack the terminal near the end, he can hack anything and after he's done you just open the door and be on your way

[iambored]

wait hold up the mole rats take away your hp I never knew that my hp bar just stayed the same

[andreasfjeldvr]

You forgot the bobble head in curie’s room

[loneranger]

From experience, the use of Terran Republic weaponry in the Commonwealth is also a vary effective solution to this quest. (Ripper).

[ethanhaynes]

⚠️⚠️⚠️don’t worry about getting hit or not start the conversation with dr forsyth and say you are keeping it then when the option of just keeping will become available turn around (exit the dialogue choices) and use it then turn back around to give home the cure, same for the power cores but you have probably already seen it

[soupyjr]

That's just way more firepower then you need.

[LungsOutJem]

You forgot the most important part, Endurance. The higher your endurance is, the less likely you'll get a disease.

p.s. It is explicitly said that Bobby and Tina are siblings. Very explicitly, several times.

[packetieee]

I save scummed this about 20 times but keep getting the mole rat disease, even if they don't hit me! I even jumped up on a shipping container on the middle platform where they couldn't reach me and I got the disease. Either they have a spit attack or they changed the quest to automatically give it to you.

[jonnymars]

Sorry not to be disrespectful you probably didn’t know but you can use power armor to negate the effect of the molests and all you need is good ap and vats and a knife mines is from the nula world dlc. And East fast kills without getting hurt or getting sick

[happymcdull-]

I'd argue robo-Curie isn't so bad in combat, since she has a built in laser pistol

[tnsie]

I just did that and oh boy it's tense, especially since I only got a semi auto max capacity pipe rifle at level 10, I got through eventually after reloading 5 times and a dozen landmines, good advice with that one

[buulecoom]

I`m surprised that you didn`t add how to get Holt Combes seeing as he`s classed as a level four merchant and you did state in your title a complete guide to Vault 81. Also are you able to leave vault 81 with the cure and then return?

[Topher]

Thanks I was walking around the vault talking to everyone and all I got was a cat finding mission. Almost sold the brother jet just to see what would happen