Why inflammation destroys the blood-brain barrier | Axel Montagne, PhD

Chronic inflammation may cause pericytes – specialized cells that sit atop brain capillaries – to detach, allowing toxic compounds and immune cells to enter the brain, causing neuroinflammation.

DHA, an omega-3 fatty acid, which might help protect the blood-brain barrier, relies on a protein called Mfsd2a to transport it to the brain. Studies in animals show that if Mfsd2a is defective or missing (which can happen with age or genetics), DHA levels in the brain decrease by more than 50%, potentially compromising the blood-brain barrier. In this clip, Dr. Axel Montagne describes the potential link between omega-3 fatty acids, inflammation, and brain health.

Interview published on Feb 28, 2023

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#omega3 #Alzheimer #brain

[mikesveganlife]

The question that comes from this clip is: Are there lifestyle things we can change that reduce the risk of age related inflammation? We know that general inflammation can be reduced through lifestyle choices. But is age related inflammation something we are just stuck with?

[mathieuguillet]

I would not recommend over doing the Omega-3, although some is good for you.

[rn]

Omega-3 can cause atrial fibrillation...