RYBELSUS - What you need to know!

Dr. Christy gives details on the pros and cons of Rybelsus, the oral GLP-1 medication for Type 2 Diabetes.

[jimfarrell]

The information you provide is so current and answers so many questions right of the bat. Thank you Dr Christy.

[VernCrisler]

Yep, I think that future improvements in the oral versions of GLP-1 / GIP drugs will be a huge game-changer, as a lot of people don't like the idea of needles.

[StarDustMoonRocket]

I started Rybelsus a few months ago. In January, a week after I went up to 14 mg/day, I got sick. Insanely sick. I was in the hospital for 2 nights. I lost 25 lbs in 2 weeks. I stopped taking the pills and I finally got better. BUT, after a few weeks of being off the drug, my hunger demon came back with a vengeance. Im going to work up to 7mg this time and not go to 14.

[TheEasyDoc]

TLDR: RYBELSUS, an oral GLP1 medication, provides the same benefits as injectable forms for type 2 diabetes and weight loss, with the convenience of once-a-week dosing and flexibility in timing and food intake.

00:00 🩺 Oral GLP1 medication RYBELSUS was approved in 2019 for type 2 diabetes, not for weight loss, but it does result in weight loss.
00:39 💡 Oral medication for weight loss is less effective than injectable medications due to breakdown in the stomach, resulting in lower hormone absorption.
01:05 💊 RYBELSUS pill has a maximum dose of 14 milligrams, which is equivalent to 0.5 milligrams of injectable seatide, but there are ongoing studies with higher doses.
01:41 💊 Rybelsus in oral form provides the same benefits as the injectable form, but with the convenience of once-a-week dosing and flexibility in timing and food intake.
02:20 💊 Take RYBELSUS on an empty stomach with water, every day, and wait 30 minutes before eating, with higher doses in development.

[botodeov]

Wygovy seems to be a better choice than Rybelsus...the biggest part of taking any GLP-1 medication is the right diet and the right amount of exercise....although no one eats their way to becoming diabetic...diet is paramount when trying to manage insulin resistance.Thanks Doc for the candid comparison..much appreciated!!

[hexmaniacciaran]

I'd rather people stay quiet about the pill form - in the UK I can't get Ozempic for my diabetes because of people abusing it for weight loss but my last diabetic review revealed that this medication might be an option for me so fingers crossed

[laurakoelling]

Thanks. I have lost about 70 pounds using semiglutide injections and now moving into year two my insurance is not wanting to cover it anymore. (Since I’m below a 30 BMI now)

So I’m hoping to maybe move this to this as a maintenance drug.

[cmah]

Are the side effects of the oral version similar to the injectable version?

[bowesman]

I'm glad I watched this, my Dr. gave me a thirty day sample today and said take it with food first thing in the morning. Nothing about water. Can you tell me about my protonics? I take that first thing on empty stomach. should I not take it till later or take it well before the Rybelsus 3 mg ? T Y

[TheMilpitasguy]

I've been on Rybelsus 14 mg for about 3 months now. I've lost about 20 lbs but have since hit a plateau. Getting that extra 5 more pounds is a struggle.

[carolinareaper]

What if I need to take the thyroid medication in the morning on empty stomach as well?

[forestpkguy]

are there any problems with constipation on high doses of Rybelsus?

[Mrpegs]

I am due to start 3 mg oral form of Rybelsus soon due to Metformin giving me terrible stomach issues. My A1C for type 2 is managed well, just a change due to the Metformin issues. Christy should I stay on Metformin as stomach issues seem to a problems with Rybelsus?. My weight is good no real interest in the weight loss aspect

[njperuviankid]

Do you have links of studies done on a higher dose ? How does rybelsus affect you overall after withdrawal?

[karlapeli]

I'm on last injection of Ozempic 2mg my doctor wants me so start Rydelsus 14mg the following week. He said I don't need to start on a low dose just start with 14mg. I'm concern, Is that normal?

[mieketelkamp]

I'm going to ghana (vacation) and I wonder if I can take malerone (malaria tablets) when I also take rybelsus?

[seydakarabudak]

I started taking rybelsus 7 mg a few days ago. My doctor immediately prescribed 7mg. the second day I was very sick. The third day I did not take it. The fourth again I did.
I read everywhere that I should build it up and start with 3mg first, but the doctor prescribed 7mg right away.

Can I take it like that every other day? I notice that this is better and it doesn't make me sick.

[jacoll]

During the initial 60 days, I shed 30 pounds by using Rybelsus at doses of 3mg and 7mg. Yet, in the subsequent 60 days, I've observed no further weight loss while consuming Rybelsus 14mg, and my hunger levels remain unchanged. Is this lack of progress typical, and would it be wise to persist with Rybelsus 14mg? Thank you

[urgx]

Bioavailability & RoA, pretty simple

[doctoralibrahimg]

I tried Ozempic 2mg for weight loss. I use it for 10 weeks with mild appetite suppression. Then I used Rybelsus 14mg and I found it much more effective for appetite suppression. I’m thinking to take higher doses hoping to get better appetite control. I think it worth to try Rybelsus if Ozempic is not satisfactory effective.