New and More Dangerous Cholesterol Found In Your Blood (Lipoprotein(a) - LPa)

Lipoprotein(a) or Lp(a) is a type of lipoprotein that consists of a cholesterol-rich LDL (low-density lipoprotein) particle linked to a unique protein called apolipoprotein(a). Elevated levels of Lp(a) are associated with an increased risk of cardiovascular diseases, as it may contribute to the development of atherosclerosis.

Lp(a) appears to have a role in the early stages of blood clotting and may interfere with the breakdown of blood clots. High levels of Lp(a) are considered a risk factor for coronary artery disease and other cardiovascular problems. However, the exact mechanisms by which Lp(a) contributes to these issues are not fully understood.

It's worth noting that while Lp(a) is a risk factor, managing overall cardiovascular health involves a combination of factors, including lifestyle changes, diet, and, in some cases, medication.

Medical emergency
Do NOT use the Video for medical emergencies. If you have a medical emergency, call a physician or qualified healthcare provider, or CALL 911 immediately. Under no circumstances should you attempt self-treatment based on anything you have seen or read on the Video.

General information is not medical advice
The general information provided on the Video is for informational purposes only and is not professional medical advice, diagnosis, treatment, or care, nor is it intended to be a substitute therefore. Always seek the advice of your physician or other qualified health provider properly licensed to practice medicine or general healthcare in your jurisdiction concerning any questions you may have regarding any information obtained from this Video and any medical condition you believe may be relevant to you or to someone else. Never disregard professional medical advice or delay in seeking it because of something you have read on this Video. Always consult with your physician or other qualified healthcare provider before embarking on a new treatment, diet, or fitness program. Information obtained on the Video is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment.

#cholesterol #diabetes #health #healthylifestyle #nutrition #hearthealth #healthy #heartdisease #bloodpressure #weightloss #fitness #healthyliving #highbloodpressure #wellness #healthyfood #kolesterol #diet #heart #hypertension #cholesterolfree #bloodsugar #heartattack #obesity #inflammation #detox #over #type #hearthealthy #healthyeating #stroke

[danteburritar]

LDL and LP(a) are not cholesterol - they are containers that carry cholesterol inside them (just as HDL does). Our bodies re-use normal LDL (re-fill them with cholesterol) but cannot re-use LP(a). LP(a) can’t go back into the liver to be re-used as it won’t fit the receptors due to the extra protein. Hence LP(a) builds up and only reduces by being destroyed. Hence how one treatment for some people, in parts of europe for example, is filtering LP(a) out of the blood but that’s something that has to be done in a hospital and often so not practical for most people. It seems likely that LP(a) and the fact that atherosclerosis and plaque problems resulting in heart attacks requires arterial damage via inflammation (from smoking and too high blood sugar for decades - think high carb diets). This goes some way to explain some people who have heart attacks but don’t have high LDL and some people who have high “cholesterol” values that don’t have heart attacks. It’s worth noting that there is no LP(a) in dietary foods that contain cholesterol. Ergo, dietary cholesterol is pretty safe, and for many - people with LP(a) - it is preferable to the cholesterol that our liver makes. Remember that we would die without cholesterol, our bodies make more if it is needed, so if you eat plenty of dietary cholesterol then your body won’t feel as great a need to make as many cholesterol containers (lipoproteins) including the LP(a) type. Large fluffy LDL is actually healthy and good like HDL, it is small lipoproteins like some oxidised LDL and LP(a) particles that cause a problem : but only when the open door of arterial damage is already present. Cholesterol itself that lives inside the HDL, LDL and LP(a) is not the bad guy, things that cause inflammation are the bad guys that open the door. The main benefit of statins in this scenario is that they will reduce arterial inflammation - so they are of use if you have damaged arteries and high LP(a) - in fact that is likely the biggest benefit of statins to most people, not the cholesterol reduction. I had a WidowMaker heart attack 4 years and have made it my business to research this subject best I can - I recommend the videos with Thomas Dayspring and Ford Brewer here on youtube.

[johnlibonati]

Just dropped in to say my grandmother had high cholesterol her whole life. Never took meds for it. Lived to 100.

[robinjones]

Perhaps one of your most interesting and fascinating vlogs yet - keep up the good work guys - many thanks from London

[hexhex]

The more informed we are, the better choices we can make. Thanks Docs

[haidersyed]

Please talk about Nattokinase, its ability to burst blood clots and shrink plaque

[boopsbucket]

Found out I have very high Lp(a) recently. I've been extremely depressed. Luckily my cardiologist is with the Cleveland Clinic. I'm thinking of asking her if there's a trial I can enter. Thank you so much for this video, it's kind of amazing that you just happened to drop it, considering I just learned this about myself. I've had a difficult time understanding it, and this has helped a lot.

[aradpd]

My father died at 32yrs old of heart attack in 1970. My brother and I both have high levels of lp(a) . Mine is 265 nmol/L (normal levels <100 nmol/L)

Over 20 years ago, we were both referred to an endocrinologist who prescribed a statin, low dose aspirin and Niaspan (which is no longer available in Canada).

Now we are both in our 50s. We have never smoked. We exercise, eat healthy diets and maintain a healthy weight.

My cholesterol is 4.66 mmol/L, HDL 2.17 mmol/L, triglycerides 0.97 mmol/L and LDL 2.05 mmol/L.

I still take a statin and low dose aspirin. My brother has been taking Repatha for about 2 years and says his cholesterol and LDL levels have dropped dramatically.

I really appreciate that your video presents elevated Lp(a) as one risk factor for heart and stroke disease. I can’t do much to influence lp(a) levels but I can make choices that can lower my overall risk factors and take charge of my health.

Thanks for the video!

[chrisbradford]

Thank you for the information. I have only recently started getting more intrusive with my cholesterol levels at 52. I requested my Lp(a) test with my doctor, and it came back at 199. I am trying to fully understand what I am facing and how to tackle it. This video has helped me understand it better!

[davidotness]

Thanks, guys. I'll be 73 in a month (if my lucky stars remain aligned) and am paying attention. I appreciate your willingness to communicate on this level.
As mentioned in a reply below, I am a newbie convert to natto kinnaise and N-AC w/ glycine daily. Remarkable results from Japanese studies.on the natto.
Again, your efforts here are much appreciated.

[kimcollard]

Thanks Gentleman
You really are Helping us to understand the Hows and Whys

[editaatteck]

Thanks for the video. Unfortunately many GPs in Ontario have no idea about lp(a) or apoB.
It took a lot of self-advocacy to convince a cardiologist to measure these markers a year ago and even today.

[jmarti]

Super informative as always, got my physical with my Dr tomorrow, I will request the LPa test to be part of my blood work.

[matthewgraham]

Docs and guest, thanks for this one. Appreciate the time you put in to make these videos.

[JMK-vopv]

Thank you, gentlemen, for the informative video. Could you please direct me to JUST ONE trial, paper, study that proves CAUSATION between Lp(a) and atherosclerosis, NOT just a bunch of associative/correlation studies?

[AngloFrancoDane]

I had a heart attack 6years ago. This year my cardiologist ordered the LP(a) test and I was very high, very high risk. He put me on Praulent (on top of my statin). I have always done a lot of exercise, never smoked, never been overweight. Sometimes you just can't win.

[stevemc]

I had 256 mmol. I started 500mg niacin . 3 months later I tested and the new number was 186. I then went to 1000mg/day and after 3 months I tested again - 156. I’m now on 1500/day and I’ve been on it for 3 months. Getting tested again today.🤞
So from my experience you can lower it. I also take the equivalent amount of TMG (as per advice from Chris Masterjon), Nattokinase twice daily to reduce clotting factors and berberine because there are some reports that it can have a slight PCSK9 inhibition. Plenty of fish oil too for blood viscosity. I also give blood every 3 months, again to reduce viscosity. Oh and make sure your niacin is the flushing type. Non flushing won’t work. I hope this helps someone because I put many many hours into researching this.

[xj]

My doctor gave me a requisition for this blood test about six months ago, but I didn’t bother to get it done. After watching your video I’m making an appointment tomorrow morning.

[richardmonson]

Great video guys. Please never stop saying “you are in charge of your own health.”

[studentaccount]

Thank you so much!! I need to look at my lab work. I think I saw that and did not know what it was. There were no flags next to it. I had good HDL level and low VLDL. Dr. Lustig a author just wrote a book and was saying the ratio of Triglyceride to HDL was important. I would love to hear more on this. TY again!

[jmcenterprises]

Thanks Docs-I have high LPa and I have had heart attacks. Going by feel alone (chest pressure/pain), diet and lifestyle affects everything. When I eat clean-very low fat, almost vegan, I feel like I am 30 years old again. L-arginine and balsamic vinegar on leafy greens supposedly increases nitric oxide, protecting the arteries. I believe that the clean diet and exercise makes the arteries LPa-proof. Caldwell Esselstyn also states this (well known heart surgeon-recommend his book and diet). Your videos are the best! Thanks again.