Your Brain on Stress and Anxiety

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Stress is the way our bodies and minds react to something which upsets our normal balance in life. Stress is how we feel and how our bodies react when we are fearful or anxious. Some level of stress has some upside to mind and body function to enable us to react in a positive way. Too much stress though, is both harmful to the body and our performance. How much is too much? Well, that depends... on you and how you respond.

It is essential to know how our brain responds to the stimuli which trigger an anxiety response so that you are equipped to deal appropriately with anxiety.

Let me highlight the key areas of your brain that are involved, and then I will explain what happens inside the brain.

The Thalamus is the central hub for sights and sounds. The thalamus breaks down incoming visual cues by size, shape and colour, and auditory cues by volume and dissonance, and then signals the cortex.

The cortex then gives raw sights and sounds meaning enabling you to be conscious of what you are seeing and hearing. And I'll mention here that the prefrontal cortex is vital to turning off the anxiety response once the threat has passed.

The amygdala is the emotional core of the brain whose primary role is to trigger the fear response. Information passing through the amygdala is associated with an emotional significance.

The bed nucleus of the stria terminals is particularly interesting when we discuss anxiety. While the amygdala sets off an immediate burst of fear whilst the BNST perpetuates the fear response, causing longer term unease typical of anxiety.

The locus ceruleus receives signals from the amygdala and initiates the classic anxiety response: rapid heartbeat, increased blood pressure, sweating and pupil dilation.

The hippocampus is your memory centre storing raw information from the senses, along with emotional baggage attached to the data by the amygdala.

Now we know these key parts, what happens when we are anxious, stressed or fearful?

Anxiety, stress and, of course, fear are triggered primarily through your senses:

Sight and sound are first processed by the thalamus, filtering incoming cues and sent directly to the amygdala or the cortex.

Smells and touch go directly to the amygdala, bypassing the thalamus altogether. (This is why smells often evoke powerful memories or feelings).

Any cues from your incoming senses that are associated with a threat in the amygdala (real or not, current or not) are immediately processed to trigger the fear response. This is the expressway. It happens before you consciously feel the fear.

The hippothalmus and pituitary gland cause the adrenal glands to pump out high levels of the stress hormone coritsol. Too much short circuits the cells of the hippocampus making it difficult to organize the memory of a trauma or stressful experience. Memories lose context and become fragmented.

The body's sympathetic nervous system shifts into overdrive causing the heart to beat faster, blood pressure to rise and the lungs hyperventilate. Perspiration increases and the skin's nerve endings tingle, causing goosebumps.

Your senses become hyper-alert, freezing you momentarily as you drink in every detail. Adrenaline floods to the muscles preparing you to fight or run away.

The brain shifts focus away from digestion to focus on potential dangers. Sometimes causing evacuation of the digestive tract thorough urination, defecation or vomiting. Heck, if you are about to be eaten as someone else's dinner why bother digesting your own?

Only after the fear response has been activated does the conscious mind kick in. Some sensory information, takes a more thoughtful route from the thalamus to the cortex. The cortex decides whether the sensory information warrants a fear response. If the fear is a genuine threat in space and time, the cortex signals the amygdala to continue being on alert.

Fear is a good, useful response essential to survival. However, anxiety is a fear of something that cannot be located in space and time.

Most often it is that indefinable something triggered initially by something real that you sense, that in itself is not threatening but it is associated with a fearful memory. And the bed nucleus of the stria terminals perpetuate the fear response. Anxiety is a real fear response for the individual feeling anxious. Anxiety can be debilitating for the sufferer.

Now that you know how anxiety happens in your brain, we can pay attention to how we can deliberately use our pre-frontal cortex to turn off an inappropriate anxiety response once a threat has passed.

I highly recommend that you also check out Lisa Feldman Barret's book on How Emotions are Made as this new research questions the assertions I make in the video (yes, I was probably wrong :-))

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Let's not feel alone, if you suffer from Anxiety like this post ❤️

KitKat-cveu
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I had a car accident back in 2019 and haven’t been the same since. Some days are better than others but usually I wake up knowing what kind of day I’m gonna have. The crippling waves of anxiety is ruining me internally. I’m trying my best to keep going but it’s hard. Hopefully one day I am free from it completely.

jaygotfitz
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glad I'm not alone in this whole anxiety thing

anthonyariza
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I've had anxiety depression and with insomnia for 5 year's and still going seeing a phycologist physicist support worker and CPN (community psychiatric nurse) am from the UK Scotland and no one has explained like you just have knowledge is power I would like to say a big thank you for making this video and there should be a lot more like you thanks again Dr

alanmcewan
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Man I cant get over how good his handwriting is.

alexbombomb
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This is the first video I've found that really breaks down what's going on in the brain during anxiety. I wanted to have an understanding of this so that I could better decide what treatments and therapies I would prefer. This was so helpful, I love that you even explained the difference between fear and anxiety as I never understood them in that light before.

sabrinalee
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the echos in his voice and that intrusive music are causing me anxiety

jsa
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+Heather Rassman
You've said it yourself.As the sun goes down your mind starts spiralling down too... I would suspect that during the day you are busy and there's a whole lot going on. Your senses are taking in tons and tons of information. Your mind doesn;t have the time to process all of the information until you start to switch off for the evening. Then your mind starts to process everything. Using the memories of the day and previous days and extrapolating something useful and somehow causing you to think fearful thoughts of tomorrow and the future - or what we call anxiety.
A word can trigger it because your memory associates that word (or tone of voice for example) with a bad outcome - whether real or not, your mind perceives it as sufficiently real. And of course, your body is responding to the flush of the neuro chemicals produced by your thinking.
In short... it's normal for it to get worse at night. But that doesn't help you. There are some short term fixes to help, deep breathing works a treat. Deliberately laugh out loud. Nothing funny needs to be happening, just force a laugh... your body and mind will get the signal that you are laughing and therefore you must be happy. Smile too. deliberately and force it, can help.
Personally, I read the bible and pray and sing when I'm feeling anxious. Anything but dwell on whatever thinking is going on.
Talk to someone you trust about it. A (medical) doctor, a pastor, a friend, enlist help from people IRL. You'll find that you are far from alone in suffering this - it's just the degree to which some endure.
Hope this helps in some way.

DrJohnKenworthy
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This has been the best breakdown on HPA Axis function.

EveretteCrudup_AMFT
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I suffer anxiety / stress and when I sleep at night my heart feels like it's going to explode when I'm trying to sleep

BlackAM
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My therapist gave me a playlist of videos to watch before we start Expsoure Therapy for Trauma. Thanks for using "real english"! I just wanted you to know that therapists are using your work with clients, so please, keep up this important information and congratulations!

chroniceverything
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I can't express how much stress relief I felt after understand this

michaeljohnston
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Audio-visual presentation complimented by synchronised commentary simplifies the complex topic of Anxiety. Brilliant presentation John.

deepaknayyar
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Im a graduate student and I love learning about the brain. This has helped me explain to my clients whats going on in their bodies in an easy way so that they can understand! awesome!

iusebigwords
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i have had anxiety for 18 years! wish i could turn it off, I just cant be alone and it hurts because i dont want to depend on my family i want WORK, to go see waterfalls, safaris, see the states, take a boat ride in venice, swim with dolphines, take my children to disney land, make money for charities, do marathons...seems impossible althiugh i feel it is possible...somehow

danielleyland
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Great explanation. To feel better reduce negative thoughts with a simple practice. Your breathing is closely related to the brain [mind] and gives good relief from stress-anxiety. To relax sit on a chair or lie down, neck straight, eyes closed and observe the sensations of your incoming--outgoing breath at the entrance of the nostrils for 5-10-15 minutes or more. Don’t fight your thoughts. With daily practice the mind will relax. No deep breathing needed. Do the practice without any expectations. When taking a walk, at office, in school, when reading, before sleep etc observe your breath sensations. Like me, make this a lifetime daily habit to have a good life. Reduce negative media and avoid constipation as it affects the mind instantly. Best wishes--Counsellor.

shyaaammeneen
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thank you for this. all the information is simple and understandable and actually makes sense (as someone who isnt educated in this field.). you put some of my own struggles into words and taught me things i was wondering about already.

AlienZizi
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This was illustrated beautifully!

Anxiety has been the most frustrating sensation I’ve ever experienced... It had subsided for a few months after my 1st couple of panic attacks, then I reached out to my MD and agreed to start the trial of Zoloft (25mg).

The irony of side effects is that it spikes the anxiety within the first few weeks, so between the nausea and anxiety it really tests your will to continue. I’m just starting my 3rd week, but the sweaty palm/feet is another dump that has been frequent... hoping it begins to subside in the next few weeks, but I have felt better overall. It’s just those random anxiety spikes that freak me out.

Thanks Dr. John!

ER_aka_RAM
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Everything I've experienced fully supports all of the claims you have made in this video. 10/10 I really was perplexed as to how the brain really functioned in these situations and as for what purpose. Thank you for the knowledge.

adamzaum
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This is the best & most succinct explanation of how stress & anxiety works.

nrosko