Obsessive-Compulsive Disorder (OCD) - Quick Guide on Neurobiology, Diagnosis and Management

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The hallmark of obsessive-compulsive disorder (OCD) is the presence of obsessions and compulsions. It has a bimodal incidence with peaks occurring in late childhood/early adolescence and again in early adulthood (20-29).
The cortico-striatal-thalamic-cortical loop (CSTC) is considered the critical brain circuit involved in the phenomenology of OCD. The CSTC circuit plays an essential role in information processing.
Treatment consists of
SSRIs and ERP (CBT)
Second line treatments are discussed.
We also cover the treatment algorithm.
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Thanks. The book "30 Days to Reduce Anxiety" by Harper Daniels was also helpful.

sunset
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Sir, please make a separate video to elaborate on the roles of Direct and Indirect pathways of fronto-striatal circuit which is crucial in understanding neurobiology of OC pathology.

mr.anindyabanerjee
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How would one suppress the expression of Annexin A1?

raybellows
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Sir, does PFC help human to control their sexual desire every time it occurs?

Sir please let me know your valuable remarks 🙏

pritamshil