Type 1 diabetes therapy shows promise for long-term reversal

A collagen formulation mixed with pancreatic cells, developed by Purdue University researchers in collaboration with the Indiana University School of Medicine, is the first minimally invasive therapy to successfully reverse Type 1 diabetes within 24 hours and maintain insulin independence for up to 90 days, a pre-clinical animal study shows. For diabetic dogs, the treatment is already in a clinical stage of testing.

Featured Purdue University engineers:
Clarissa Hernandez Stephens, PhD Candidate, Weldon School of Biomedical Engineering
Sherry Harbin, Professor, Weldon School of Biomedical Engineering and Basic Medical Sciences, College of Veterinary Medicine

Purdue and the IU School of Medicine collaborated on this work through the National Institute of Health T32 Indiana Bioengineering Interdisciplinary Training for Diabetes Research Program, which awarded a fellowship to Stephens to develop innovative technology for the treatment of diabetes.

The collagen formulation is a patented technology. This research was also supported by the National Science Foundation Graduate Research Fellowship (DGE-1333468); the Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Pilot and Feasibility Program (P30DK097512); and generous donations from the McKinley Family Foundation.

Thanks to Purdue Veterinary Medicine, Jan Goetz, and Lexi.

#diabetes #biomedicalengineering #purdue #islettherapy #t1d #nsffunded

Known as the “Cradle of Astronauts,” Purdue University's College of Engineering’s long list of pioneers includes Neil Armstrong and Amelia Earhart. Purdue Engineering is among the largest in the United States and includes 13 academic programs and ranked Top 10 nationwide by U.S. News and World Report.

[deliaramirez]

This is great news. I have a 25 year old grandson who struggles with Type 1 diabetes. This research leading to successfully reverse Type 1 diabetes within 24 hours and maintain insulin independence for up to 90 days, would be a life changing event for all type 1 diabetics!!! God bless you and the work you do.

[cindyp]

Where can we find updates on this therapy for humans? It's been 2 yrs since this was posted. Thanks!

[terimorris]

I've been waiting for this since my diagnosis at age 8, forty years ago!

[simad]

May God give success to this therapy and may it come into utilisation as soon as waiting for some miracle that can change life of my 27 year old

[miaarlo]

Where can you sign up for human trials?

[scooney]

I have got T1 you ever need a human patient when it comes to trial sign me up. Would love to try and get a leg up on this awful disease

[fbaddini]

Hello, please what is the status of this project?

[jaazcuckow]

Have they gotten any further with this? My little girl got diagnosed at age 3 and she is now 4 she’s had it 1year and it’s not getting any easier

[angelechavarria]

those are amazing news! thanks a lot for sharing!

[JB-oryh]

Will this therapy require the human patient to take immunosuppressants?

[georgiaallan]

The collagen is OK, but where are the islets from? From humans, or from pigs?

[moggers]

Is there anything new about this? I’m begging here 🥴