Chronic Kidney Disease (CKD) | Etiology, Pathophysiology, Clinical Features, Diagnosis, Treatment

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You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:

Ninja Nerds!
In this lecture Professor Zach Murphy will be presenting on Chronic Kidney Disease (CKD). During this lecture we will be starting with a discussion on the most common causes of CKD. We will then transition into the pathophysiology and most common clinical features associated in patients with CKD. We will then conclude this lecture with the diagnosis, treatment, and complications of CKD. We hope you enjoy this lecture and be sure to support us below!

Table of Contents:
0:00 Lab
0:08 CKD Introduction
0:29 Causes of CKD
24:59 Pathophysiology and Clinical Features of CKD
48:28 Diagnosis of CKD
1:02:54 Treatment of CKD
1:24:45 Comment, Like, SUBSCRIBE!

References:
● Brunton, L., Knollman, B., & Hilal-Dandan, R. (2017). Goodman and Gilman’s The Pharmacological Basis of Therapeutics, 13th Edition. McGraw-Hill Education.
● Ross, M. H., & Pawlina, W. (2015). Histology: A Text and Atlas: With Correlated Cell and Molecular Biology (7th ed.). Lippincott Williams & Wilkins.
● Le, T., Bhushan, V., & Sochat, M. (2021). First Aid for the USMLE Step 1 2021, Thirty First Edition (31st ed.). McGraw-Hill Education / Medical.
● Gabriel, D. (2019). USMLE Step 2 CK: A Student-to-student Guide (Clinical Knowledge) (10th ed.). Independently published.
● Papadakis, M., McPhee, S., & Rabow, M. (2019). CURRENT Medical Diagnosis and Treatment 2020 (59th ed.). McGraw-Hill Education / Medical.

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Does anyone else wish we could donate some of our tuition to these great educators on YouTube like NN?

marykittredge
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Hi ! I really felt the need to come in here and say I HAVE PASSED MY PATHOPHISIOLOGY EXAM WITH A SOLID 100 !!!! And you have helped me a lot to understand the mechanisms and more than that, helped me understand my teacher's book better. It was an oral exam (basically I had to speak on those subjects and explain them to my teacher) and one of my subjects was about compensation mechanisms of CKD. Can't thank you enough for all the hard work and great videos!!!

hiniiam
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This is literally art. I can't believe teachers like you exist.

Jasmine-eztd
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Thank you. Im in the hospital now watching this with a kidney failure. You're saving lives. Please carry on you're work.

jesseglowgauge
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I work in dialysis and no one cares what we do or even knows what nephrology does. Thanks for caring about it enough to teach it!

Gregnoxy
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the most complete, detailed, didactic and illustrative presentation, with clear English articulation that is understandable to all

diwqits
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I'm having a surgery exam in 5 days and I don't know why I'm watching an internal medicine topic 😂.
We, from Egypt, love you Zack and appreciate every single ATP molecule you burnt during filming these awesome videos❤️

ahmadmusawer
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That's funny, I just had my dialysis clinical today and was like, "I wonder if there is a Ninja Nerd lecture on CKD." Just so happens that It came out today! As always, your videos are clear, in-depth, understandable, and fun to watch. Thanks so much for making them. You're one of the few channels I don't skip ads on.

christopherkraemer
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Your one lecture deserves one million dollar sir

muhammadyounas
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The Best YouTube Lecturer Ever.. Your lectures are always Very informative, Intresting and easy to Understand.

lewiskeli
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I have ckd and have been trying to get the medical community in canada to help me / support me and slow down the progress. Also have been asking questions. What is ckd? How does it happen? Why does it happen? How do we slow it down? Can't seem to get any answers, or a clear description. This is the first description/ analysis that has made any sense (after 15 years of frustration). I have CKD stage 3A. My lab work, imaging, signs and symptoms show this. Told it's "not a big deal". I'm "not on dialysis yet". I'm not "on the transplant list yet". I "have lots of time". GFR of 45 and creatinine 118. Told I'm not "bad enough" for urology or nephrology" yet. I'd like to show the medical community this. Have a feeling they wouldn't be happy to hear from me.

gaylenetingstad
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WOW! I stumbled upon this video because from a nursing standpoint I wanted to understand more about kidney failure. Your lecture with the visual illustrations really helped me understand the pathophysiology of kidney failure, causes, and treatments. Now I understand why renal patients receive certain medications and the s/s associated with kidney failure. This was the BEST educational video I've ever watched. Thank you so much for sharing your knowledge with us. Now, I hope I can find a lecture related to all things cardiovascular! :)

glow
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This guy is not teaching nephrology, he is telling stories! so much fun ! thanks~~~~

chongyangwu
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Love your vids! It’s a good pathophysiology refresher for those MDs who have done USMLE Step1 years ago. This is stuff is taught in the first 2 years of medical school, but it always come back in all the licensing exams. Good job! Oh, and I see the passion you have for teaching!

gettygets
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AMAZING, every basic students and the nephrology RESEARCHERS go through this and learn the subject of renal function both normal and disease condition. I feel how a confident voice like his can have a deep impact on learning

dibyendupanda
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I can’t express how grateful I’m for you, you make every single topic sound as if it was a piece of cake.

med
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I LOVE YOU! Thank you for explaining ESRD on a cellular level. Your style of teaching is PERFECT!
even I, a High School graduate, can easily learn and the picture drawing is the cherry on top. BRAVO!

rachelvega-gamboa
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Wow excellent lecture.

Please Continue to always educate millions of people, you are a excellent teacher. One in a million.

joelnendongo
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I'm so thankful Ninja..I'm sure my friend too are happy 😊 you've taken us through the medical course so easily

corneliuskipngetich
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Amazing...just amazing! This 1 hr video alone has done more for me than all my university lectures combined.

jessicaeze