Ozempic & Weight Loss Drugs: How They Work in Your Brain | The Oprah Podcast

In this episode of The Oprah Podcast, Oprah sits down with Dr. Ania Jastreboff, an endocrinologist and associate professor at the Yale School of Medicine, to talk about the new GLP-1 medications like Ozempic, Wegovy, Mounjaro and Zepbound. Dr. Ania, who has been on the forefront of GLP-1 medication research for the past 20 years, will talk through why it is biologically difficult for some people to lose weight, maintain weight loss, and why obesity is a disease. She explains how the new GLP-1 medications work, how they can facilitate weight loss, and if they are safe. Dr. Ania answers questions from people around the country who are taking the GLP-medications and have lost a significant amount of weight. We will also share an update from Amy Kane who told her story of losing 160 pounds on weight loss medications last year on Oprah’s ABC Special: Shame, Blame and the Weight Loss Revolution.

00:00:00 Welcome Dr. Ania Jastreboff
00:01:34 The difference between obesity and being overweight
00:03:14 Is obesity a disease?
00:05:33 Why are some people prone to obesity and not others?
00:08:28 How your brain plays a role in obesity
00:10:31 We eat more food than our bodies need
00:13:00 Oprah shares about being publicly shamed for her weight
00:14:20 Can we control our weight?
00:20:18 Why GLP-1 medications are a game-changer for so many people
00:20:58 How GLP-1 medications work
00:23:35 Amy joins Oprah to share her weight loss journey
00:26:11 The biggest misconceptions about GLP-1 weight loss drugs
00:29:00 Understanding food noise
00:31:12 Amina joins Oprah to share her weight loss journey
00:33:35 Do you need to stay on GLP-1 medications forever?
00:37:03 GLP-1 medications are not a weight loss drug
00:39:41 Emma joins Oprah to share her weight loss journey
00:42:58 Long-term effects of taking GLP-1 medications
00:48:23 Side effects of GLP-1

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