Better than NMN & NR: Future of NAD+ Boosters for Longevity | Dr. Nichola Conlon & Beyond Sapiens

In this interview with Dr. Nichola Conlon, founder and CEO of Nuchido Laboratories, we shed light on NAD+, its significance, and ways to increase it. We also delve into the scientific aspects of NMN and NR while discussing the next-generation NAD+ supplement Nuchido TIME+.

We invite you to join us in this video to gain an in-depth understanding of this important topic. Just like us at Beyond Sapiens, Dr. Nichola Conlon is on a mission to democratize science, helping people reverse their biological age and improve their healthspan.

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🔔 DISCLAIMER 🔔
The information provided in this video is for general informational purposes only and should not be considered as professional healthcare advice. No doctor/patient relationship is formed, and viewers use this information and linked materials at their own risk. This video is not a substitute for medical advice, and viewers should consult healthcare professionals for specific conditions or concerns. The creators' views are not medical advice, and no warranty is made regarding the information's accuracy or reliability. Viewers agree that the creators are not liable for any damages resulting from the use or reliance on the information. New research may supplement this content, so it's important to consult healthcare professionals and stay updated with medical literature.

00:00 Introduction
01:24 What is NAD+ & Why We Need It
03:35 How NAD+ Is Connected to Longevity
06:59 How to Naturally Increase NAD+ Levels
10:16 How NMN & NR Work
12:45 Does NMN & NR Promote Longevity
18:30 Nuchido Time+ New Generation NAD+ Booster
25:45 The Science Behind Nuchido Time+
32:23 The Future of Longevity & Nuchido
37:30 Connect With Dr Nichola Conlon
38:35 Nuchido Discount Code
38:58 Longevity Coaching

[beyondsapiens]

We're looking forward to meeting you!

[md]

Here is a summary of the key points from the video:

- NAD+ is a critical molecule for cellular energy production and repair that declines with age. Boosting NAD+ may promote longevity.

- Popular NAD+ precursors like NMN and NR may provide some benefit but don't address the root causes of NAD+ decline.

- The root causes are declining NAD+ recycling enzymes and increased inflammation. NMN and NR simply provide more raw material.

- Dr. Nichola Conlon created Nuchido TIME+ to target the root causes. It contains nicotinamide plus ingredients to boost NAD+ recycling and reduce inflammation.

- A placebo-controlled, double-blind crossover study on TIME+ showed it significantly increased NAD+ levels, NAD+ recycling enzymes, sirtuins, and reduced biological age in 28 days.

- Future Nuchido products will likely target cellular senescence.

- Dr. Conlon believes future anti-aging treatments will make age-related decline seem inhumane, much like current views on allowing cancer.

In summary, the video explains how Nuchido TIME+ targets root causes of NAD+ decline and showed significant anti-aging effects in a robust clinical trial. Future longevity treatments may make aging as we know it obsolete.

[johnwright]

I have been on NMN now for two years. I am 91 and my Bio Age is 73. I have done a number of things to keep my Bio Age down. I am highly impressed with the data in the video. Good job of presentation. I have purchased a three-month supply of NMN Time and am willing to give it a try. Hopefully my trust will be backed up by the integrity of your presentation. Thank you.

[Lantana]

As a medical person myself, i appreciate the time and commitment required to collate and concisely present such a broad and complex subject. Every bit of research and provocation of thought will lead us closer to enlightenment. Thank you for the informative video 🙏

[beyondsapiens]

The clinical trial mentioned in the video is currently being peer-reviewed. It will be published in a prestigious scientific journal, and we'll update the description with the link once available.
Thanks for your views and support!😊

[bbldb]

I’m so happy with my 76 year old energy level. A young lady I talk with said, you have the energy of someone 30 years younger, maybe I have more work to do. I MB routinely don’t eat sugar or processed food ect. Thanks for the video.

[mondolilith]

I remember when NAD supplements hit the market around a decade ago. But I didn’t really start to understand it’s precursors and pathways until I started a keto diet with IF. I am currently supplementing with niacinamide and niacin as I’m only a few months in to my new life style but plan on dropping them as I’m taking in much higher levels of these nutrients through a high fat & protein diet. I feel sooo much better!

[Dr.AnonymousPro]

I'd advice an alternative, one brand I have the best experiences with is: Greenfood. They have Vitamin B3 (Niacin) high dose. And yes, it causes the flush, but you can limit that with some tricks. The other ingredients of the rather expensive Nuchido time stuff are easily available from nature. I mean, just take the parsely and green tea fresh! Grow your own if you can.

[walterski]

What about cancer cells, wouldn't this also accelerate multiplication of cancer cells too??

[berdiberdi]

Niacin (or Ncotinic Acid) is another NAD+ precursor which isn't mentioned in the video, much cheaper than NMN and NR.

[rajeshchheda]

Nuchido is just the beginning, going ahead, we will have more cocktails and all of them will work.

[thewizardTim]

Niacin (B3) and niacinimide (nicotinamide) both enter cells through passive transport. No ATP is required. NMN must be converted into NR and then can be absorbed through ACTIVE transport.

Niacine and niacinamide are less expensive, can be taken in higher molar concentration, and are likely to be more quickly absorbed. Niacinimide is the primary and limiting storage substrate of the salvage pathway to make NAD. Ribose is present in abundance.

[Travelbythought]

I would prefer regular niacin over the non-flushing kind, as the flush has some benifits and is more gentle on the liver. It is good that there are more options out there becoming available. We are still in the early days of this research.

[metaphysicalArtist]

What is the Optimal NAD+ levels ?, and if you have way to high NAD+ levels is it BAD? - Typical NAD levels vary considerably by age and unit of measurement. NAD levels within cells can range between 10 and 1000 μM. Additionally, total NAD values were observed to range between 0.3 and 0.4 μmol/g.

[donrice]

I am 68 and notice a bigger benefit by far from creatine than i have from NAD precursors

[catman]

£60.00 for a months supply or £165.00 for 3 months as opposed to £99.00 for 100 days NMN from donotage. I'm getting great results from NMN, not sure why I should change to something more expensive.

[darkprofile]

Well in my country Nuchido products are not sold. But I saw the main ingredients of the product as Nicotinamide, Rutin, Quercetine (sophora japonica), Alpha Lipoic Acid, Vitamin C, Zinc, Green Tea extract, black pepper, and parsley. I will buy those supplements separetely and use them together with parsley and black pepper in my diet.

[michaellamont]

The HEX and Pulse Chain community will be very interested in this

[peterz]

Follow up NAD+ effects of Time+: Please correct me if math is wrong. NAD+ has a molecular weight of about 660 grams per mole. Typical NAD+ levels appear to be on the order of 40 to 60 micromolar intracellular although some google scholar papers mention blood as opposed to intracellular. The Jinfiniti site which does NAD+ testing reports in micromolar and shows optimal values roughly on the order of 50 micromolar, so expect typical baseline to be lower. Converting 50 micormolar NAD+ to ng/ml I get over 30, 000 ng/ml which is huge compared to the increase Nuchido showed of about 17 ng/ml. Calculation below.

660 grams/mole for NAD+
50 micromolar is 0.00005 mole/L
0.00005 mole/L x 660 gms/mole = 0.033 gm/L
1, 000, 000, 000 ng/gm x 0.033 gm/L = 33, 000, 000 ng/L
1000 ml/L
33, 000, 000 ng/L x 1L/1000ml = 33, 000 ng/ml
If someone here has the skill to do the conversion and check this please do as I don't want to misrepresent Nuchido's results, but so far Nuchido has not clarified what the baseline values of their subjects were or offered up typical values for comparison. One poster noted that he got 33 ng/ml but I did not see his work and he has not yet commented on my details shown above..

[fasteddylove-muffin]

My God this is deep. It's going to take a whole lot more research as far as lifestyle & diet to get those optimal NAD levels up & running.