Do NAD and NMN promote longevity?

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This clip is from episode # 300 of The Drive, Special episode: Peter on longevity, supplements, protein, fasting, apoB, statins, & more.

In the full episode, they discuss:

- The energy balance theory
- The importance of VO₂ max, muscle mass, and muscular strength for lifespan
- How to preserve muscle while trying to lose weight
- And more

Listen free (ep. # 300) on Peter's website or your favorite podcast player. Become a premium member to access our extensive show notes for this episode.

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About:

The Peter Attia Drive is a deep-dive podcast focusing on maximizing longevity, and all that goes into that from physical to cognitive to emotional health. With over 90 million episodes downloaded, it features topics including exercise, nutritional biochemistry, cardiovascular disease, Alzheimer’s disease, cancer, mental health, and much more.

Peter Attia is the founder of Early Medical, a medical practice that applies the principles of Medicine 3.0 to patients with the goal of lengthening their lifespan and simultaneously improving their healthspan.

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This is my second round with NMN and Resverstrol. Why? I took them and had severe watery diarrhea that would not stop for months. Wasn’t sure if it was the NMN and Resvertrol and searched on-line to see if this was a side effect. Nothing. It’s happened again! So I stopped, and the watery diarrhea stopped—it was seriously the worst I’ve experienced in my life. I found something on-line last night on Reddit that many people have shared the same experience. I’m done with this. It’s expensive. I’ll spend that money on my healthy lifestyle and a ripper new bicycle! Good on ya Dr. A.

winskypinsky
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thank you Mr.Attia, telling the truth about this highly hyped sales gimmick.

veramentegina
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I do boxing...when i started, i was wasnt taking any supplements AT ALL. few months in, i started creatine nmn and resveratrol.

I went from being able to spar for 1 or 2 rounds to outsparring almost every single person in the gym. Everyone talks about my stamina. I dont get tired! Sometimes, i will stop doing an exercise not because i am tired...but because i dont want to break something. There is no pain even doing pushups. My muscles just keep going.

This is great! Without steroids.

arielperez
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People and doctor’s opinions change all the time. He is super smart, but he was 100% and then time restricted feeding was the way. Now it’s all about getting enough protein in your diet. It’s about experimentation until we find out what is best for your health and longevity.

pedrocgrn
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I think healthy diet no alcohol limit sugar and daily exercise including muscle building exercises and cardio you’re going to age exceptionally well and live past 100 with a quality of life

traceykerr
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It works for me. I have chronic fatigue, so albiet thats a different category than "otherwise healthy", most doctors dont really view this as an illness, and theres not really a treatment.

chiefhiggins
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Here's my story; I'm in very good health for an individual my age (74). I've taken NMN, Resveratrol, Berberine, TMG and a host of "popular" supplements over the last 18 months. None of these protocols, either individually or collectively, have had a noticeable improvement on my quality of life.

augustmosco
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Dr David Sinclair says everyone he sees that looks extremely young for there she says they take this stuff, personally I’m on the fence about it

Longevityoptimisation
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I have taken NMN and NAD. Interesting how the impact for me seems to be that I can work out longer and harder and have less of a recuperation period afterward. Given that you don't acknowledge the science supporting longevity, how do you then rationalize the physical effects they produce?

thevibrancyreboot
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Can you describe your reasoning on the evidence to make this conclusion?

hanhai
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Pls provide the evidence of that lacks causation or correlation

briancook
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Good, less vitamins to take! I was on the fence about this stuff every time I set up my vitamins for the week. Going forward I’ll delete it from my protocol.

MOVIEKICKS
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Thank you for exposing the truth rather than joining the supplement of the month club.

alfredvincent
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I appreciate you being real if you’re not caught up in marketing but I do believe I am not either I made a decision based on research please explain why you don’t think it’s useful? Seems clever to protect the cells and help cellular energy yes ??

Sunnyfield
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I don’t want to live longer, especially as sick as I’ve been. Your relatives don’t want you to live too long either!
My grandparents each lived to be 104, and my grandfather was sad that all his friends had died.

Tinyteacher
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This guy will be dead waiting on long term studies with big enough sample size to come out on the benefits of elevated nad levels..

mattweiler
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NAC IS BETTER 🤤 especially if you smoke

actsofkindess-zr
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To each their own. Cookie cutter medicine treating everyone the same is a thing of the past.

rtgl
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Non-Metallic Metals - This guy ain't winning Golden Demon.

Xiv
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Pigeons think too so what's your point

CashewsClayy