Rewinding the clock on aging blood vessels

Investigators at Harvard Medical School have identified the key cellular mechanisms behind vascular aging and its effects on muscle health.

[Pedro-dscq]

This guy deserves all the funding he needs

[partypao]

David Sinclair and his team should win a Nobel prize, not only for the research and discoveries they have done on fighting aging, but that he is openly sharing this new knowledge to the world.

[TheLazyVideo]

This also explains balding in older men (not premature balding in 20yr olds). A good scalp vasculature is key to prevent miniaturization, since hypoxic environments promotes the impact of DHT.

[JA_Michael_]

David Sinclair is a genius, glad to share this world with him

[espperre]

Essentially, increase NMN intake. I’d stay away from supplements unless they’re pharmaceutical grade. Foods highest in NMN:
1. Broccoli
2. Cabbage
3. Cucumber
4. Edamame
5. Avocado
6. Tomato

[mcitheaterclass]

Human bodies are an astonishing piece of engineering. Makes me all the more appreciative of the Engineer.

[DingbatToast]

Whenever I'm feeling a little too high on endorphins and the wonder of life, I'll come here and watch this video and remember how old I am and how much my body is decaying as I follow life's rut ever more slowly until I'm choked to death by the very systems that brought me life. Cheers 🍻

[craigherron]

2:41 I started a regimen of 1g/day of NMN and 1g/day of resveratrol on 10/1/22. Within two weeks, the lower leg edema that I had been experiencing for several years completely went away. On top of that, my recovery time from daily pickle ball was very significantly shorter, and no more calf muscle pulls. None. I have been on the regimen for roughly two and a half months. I will never stop.

[RightURKen]

NMN = Nicotinamide mononucleotide- It's an over the counter supplement for those of you wondering.

[ladoparts]

Thats very encouraging news and remarkable that a naturally occuring product in our body would be the catalyst that reinvigorates the others and reverses the condition

[sotoskaragianis]

Thank you dr David, I just bought your book lifespan !you are my hero! Congrats !

[davidollen]

David Sinclair you are a genius your theory on epigenetic aging would also explain the cambrian explosion of species as well as aging. Neat when one new theory explains an old conundrum.

[ritahiggins]

Thank you. Are there any other foods or herbs besides these that increase NMN?
1. Broccoli
2. Cabbage
3. Cucumber
4. Edamame
5. Avocado
6. Tomato

[cmac]

All the Tour de France winners: "They're still using rats?"

[farshm.]

Excellent work, Doctor. I'm rooting for you to make an awesome discovery soon.

[jlushefski]

It's refreshing to see a scientist have a genuine interest in discovery in his field--though not that you can tell from this short video. There are other Harvard scientists, like Wrangham and Willet, who seem to be preoccupied with self-promotion, and science takes a backseat.

[js.]

By watching ads, this channel gets more views & support. Tnx.

[bennyvarughese]

David you are a genius. A thousand likes for you.

[almedogjurgji]

Always knew that M&Ms were magical 😋

[urielstud]

Dear David, Although I found NMN to be a rather strong diuretic that’s sometimes convenient, Nicotinamide Riboside seems to do the trick for me. It’s a little pricey so you can also try regular Niacinamide (Vitamin B3, Niacin) as a NAD+ booster. Along with Resveratrol, it may be the “15 year pill” here for us already!