mRNA Processing in Eukaryotes - Capping, Splicing, Polyadenylation | Pnkj Verma Sir

In molecular biology, messenger RNA (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene and is read by a ribosome in the process of synthesizing a protein.
Transcription is when RNA is made from DNA. During transcription, RNA polymerase makes a copy of a gene from the DNA to mRNA as needed. This process is slightly differs in eukaryotes and prokaryotes. One notable difference, however, is that prokaryotic RNA polymerase associates with DNA-processing enzymes during transcription so that processing can proceed during transcription. Therefore, this causes the new mRNA strand to become double stranded by producing a complementary strand strand know as the tRNA strand. Furthermore the RNA is unable to form structures from base-pairing. Moreover, the template for mRNA is the complementary strand of tRNA, which is identical in sequence to the anticodon sequence that the DNA binds to. The short-lived, unprocessed or partially processed product is termed precursor mRNA, or pre-mRNA; once completely processed, it is termed mature mRNA.

mRNA is created during the process of transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and, utilising amino acids carried by transfer RNA(tRNA), the ribosome creates the protein. This process is known as translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of genetic information in a biological system.

Watch my other videos👇👇👇

Molecular Genetics - All lecture-

Extra Gyan👇👇👇

Strategies for Enhancement in food production-
All videos-👇👇👇

Microbes in Human welfare-
All videos--👇👇

Biotechnology (complete unit)-👇

Animal tissues- (All lectures)--👇👇

Human Health and Disease (All lectures)--👇

Body Fluids and Circulation--👇👇

For any other information or queries, you can use comment box or you can mail me at-

[malleshwarig]

Thanku so much....i was having seminar tomorrow of this topic.. literally i was struggling what to do but ur video helped me lot and so good explanation 😊

[barshabiswas]

After lots of struggle...finally can understand

[ashwinimurthy]

Sir capping explanation was bang on 👌🏼... Tnk u

[anitaprajapat]

Thank you so badi help ki h aap ne 🙏🙏🙏

[MukeshBK-rupf]

after seen many videos i hold here what a explanation

[hafsariaz]

Your way of teaching is very good👍 you make the things very simple for understanding 👍

[suchismitasahoo]

After lot of struggle I found this video it is very you so much sir for explaining it very simple language 😊

[sanaiqbal]

Sir you are a true gem 💎 please start your online coaching centre for the preparation of csir net ..we want to join you ...

[quotesworld..]

That was so easy to understand thank you sir

[ayeshafarhad]

or best video hy, bht try ki thi me n but smjh ni a re thi ab agayi thanks a lot

[sawanpandey]

Thank you so much sir 🙏❤️
You made it more esier

[nishakumawat]

Wow sir kya ..smjate ho ..aap ..hme .. almost classes me ye ni btaya jata h ki...post translation kha h ..kis jgh se strat horha h..aapka video bohot helpful hota h...tnx u .sir.. God bless you 👍👍

[manishamohil]

Thankyou sir you made the concepts clear☺

[niveditabhosale]

Khup बेसिक पासून start karun छान expain केले आहे

[NibeditaMoharana-khpy]

Thank you sir This video lectures are very very helpful for me❤

[pooonampatel]

You are great teacher, thanks you so much sir 😊😊😊..

[sarafathima]

Thnk u so much sir ❤ aap na mare badi problem solve kardi thnk u so

[amnayat]

Thank you so much too u infact for such a simple+ easy lecture 👏👏👏👏

[ChBaga-sq]

Very simple explanation Thank you so much sir😊

[ankitameher]

You make every step so much easier with great explaination .... thank you sir👍☺️