filmov
tv
RNA Splicing
Показать описание
A 3D animation shows the crucial RNA editing step called splicing
TRANSCRIPT:
As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. This editing process is called splicing, which involves removing the introns, leaving only the yellow, protein-coding regions, called exons.
RNA splicing begins with assembly of helper proteins at the intron/exon borders. These splicing factors act as beacons to guide small nuclear ribo proteins to form a splicing machine, called the spliceosome. The animation is showing this happening in real time. The spliceosome then brings the exons on either side of the intron very close together, ready to be cut. One end of the intron is cut and folded back on itself to join and form a loop. The spliceosome then cuts the RNA to release the loop and join the two exons together. The edited RNA and intron are released and the spliceosome disassembles.
This process is repeated for every intron in the RNA. Numerous spliceosomes, shown here in purple, assemble along the RNA. Each spliceosome removes one intron, releasing the loop before disassembling. In this example, three introns are removed from the RNA to leave the complete instructions for a protein.
TRANSCRIPT:
As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. This editing process is called splicing, which involves removing the introns, leaving only the yellow, protein-coding regions, called exons.
RNA splicing begins with assembly of helper proteins at the intron/exon borders. These splicing factors act as beacons to guide small nuclear ribo proteins to form a splicing machine, called the spliceosome. The animation is showing this happening in real time. The spliceosome then brings the exons on either side of the intron very close together, ready to be cut. One end of the intron is cut and folded back on itself to join and form a loop. The spliceosome then cuts the RNA to release the loop and join the two exons together. The edited RNA and intron are released and the spliceosome disassembles.
This process is repeated for every intron in the RNA. Numerous spliceosomes, shown here in purple, assemble along the RNA. Each spliceosome removes one intron, releasing the loop before disassembling. In this example, three introns are removed from the RNA to leave the complete instructions for a protein.
0:01:38
RNA Splicing
0:08:05
RNA Splicing Mechanism
0:06:53
Splicing
0:02:11
RNA Splicing
0:05:12
What is RNA splicing?
0:01:20
An Explanation of RNA splicing
0:09:33
RNA splicing and Spliceosome
0:05:33
mRNA splicing
1:49:41
VOE ALTO NA BIOLOGIA DA UFRGS (DIA 2)
0:04:55
Splicing
0:10:28
splicing mechanism and its importance (overview) | How does splicing happen? | Molbio
0:03:51
The Experiment that Discovered RNA Splicing
0:23:32
RNA splicing and processing | RNA splicing mechanism | spliceosome
0:16:22
Phillip A. Sharp (MIT): RNA Splicing: What is a Gene?
0:09:07
RNA splicing
0:05:56
Can RNA Splicing Errors Cause Disease?
0:28:56
Anna Marie Pyle (Yale U./HHMI) Part 2: Inside an RNA Splicing Machine
0:03:31
Just What is RNA Splicing?
0:11:27
Posttranscriptional modification (hnRNA to mRNA) Splicesome, Splicing, Cap, Tail, Introns, Exons
0:08:03
RNA Prozessierung [Proteinbiosynthese, 2/3] - [Biologie, Genetik, Oberstufe]
0:00:30
RNA Splicing by the Spliceosome: Supplemental Video 2 - Assembly of the A complex
0:27:10
Moleküler Biyoloji ve Genetik Dersleri #49: RNA Splicing
0:02:51
RNA Splicing Animation | self splicing
0:00:56
Drug Therapies Based on RNA Splicing
Комментарии