Methylation | The Best Kept Optimal Health Secret

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In today’s solo episode, Gary takes you through his career journey from assessing mortality risk for life insurance companies to starting a wellness franchise. He’ll share his experiences applying his knowledge of biomarkers and genetics to treat patients by looking at the root causes of disease. He’ll discuss his decades of research, striving to add not just years to your life but life to your years. He’ll also explore the role of gene mutations and nutrient deficiencies, focusing on the MTHFR gene mutation that affects up to 44% of the population and the impact it has on our body's ability to convert folic acid into methylfolate. He discusses the wide range of issues a deficiency in methylation can lead to, including anxiety, depression, and poor gut health. Listen in as we unravel the effects of a gene mutation called COMT on conditions like high blood pressure, hypothyroidism, hypercholesterolemia, and estrogen dominance. Learn how nutrient deficiencies can be the cause of common ailments, and how supplementing with the right nutrients can help restore things like estrogen balance. Join us on this journey towards becoming an Ultimate Human.

Additional Topics Covered Include: Anxiety, ADD, ADHD, OCD, Gut Health, and Brain Fog

The 2 Ingredients to Avoid In Your Supplements: Folic Acid and Cyanocobalamin

--------- EPISODE CHAPTERS ---------

(0:00:00) - The Ultimate Human

(0:10:45) - Discovering Gene Mutations and Nutrient Deficiencies

(0:22:05) - The Role of Methylation in Health

(0:28:20) - The 2 Ingredients to Avoid in Your Supplements

(0:29:43) - Gene Mutation and Hormonal Imbalance Solution

(0:35:38) - Improving Health Through Natural Practices

JOURNAL ARTICLES REFERENCED IN EPISODE:

Associations of Depressive and Anxiety Symptoms with 24-hour Urinary Catecholamines in individuals with untreated high blood pressure:

MTR and MTRR Genes: Methylation cycle and the need for Vitamin B12:

Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice:

Mitochondrial translation requires folate-dependent tRNA methylation:

MTR and MTRR Genes: Methylation cycle and the need for Vitamin B12:

On the mechanism of homocysteine pathophysiology and pathogenesis: a unifying hypothesis:

The Ultimate Human podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

[saratonnan]

At 73 I was just diagnosed with the MTHFR mutation. Most of the symptoms he listed I have been dealing with my whole life. Started on the right supplements & it changed my life. I grieve for "what might have been" a happier life, yet am so very thankful for finally having the answers. ❤

[AnimaPerdida-rwpu]

I'm a nurse, I've met and gotten to know many doctors, and let me just say, you know much more than they do and are more ethical than them

[piperuk]

Methylated B complex has changed my 12 yr old son in the most incredible ways! ❤

He was quite frankly an odd boy: Hyper, stressful, inappropriate, histrionic, displayed constantly changing "ticks", lacking in focus, ADHD symptoms, lacking in empathy, showed no remorse, bad sleeper. Quite the list!!

I had a COMPLETELY DIFFERENT SON in 3 weeks and now 2 months on he is unrecognizable. I could cry with elation. Best of all- His 18yr old sister who genuinely couldn't bare to be in the same room as him, now chats and laughs with him. I could not be happier!!❤

[sirvikalcrusader]

Hi Gary. Chiropractor and functional medicine Doctor from the UK here. Just to say thank you for all you do...the bio hacking, health optimisation movement is going off the chart. And its largely due to people like you who have stepped up to the plate. God bless you Sir.

[frankc]

I’m not wealthy like his clients, but do exactly what he says to do. He is providing a ton of valuable information for free. Thank you!

[jrstrange]

1. First light
2. Deep breathing
3. Cold shower b/f exercise
4. Grounding
Sounds silly but these techniques are highly affective!

[renemalekian]

My graduate thesis was on DNA methylation and how CpG islands control expression of genes. Gary makes a lot of sense.

[Fonzarelli]

Im thankful for humans like this that are willing to translate this information into english in a calm confident and caring demeanor.

[cruisinjesus]

I am a retired truck driver of 22 years do to poly neuropathy and fibromyalgia since 2002. I just did my 10x dna test and waiting on new vitamins etc to turn my self around and guess what I have been taking bad vitamins for over 30 years ughhh. We also just received our hydrogen water bottles. Excited to get healthy Thank You Gary God Bless You…

[amd]

Would love an episode on menopause and things us women can do to help with the weight gain.

[ilianaluna]

We need more education like this for our physicians not pharma driven. I lost a mother to an autoimmune and now have a daughter with an autoimmune. I can’t emphasize enough how knowledgeable this man is! It makes sense and wish I would have followed or heard about him before my mother passed. Thank you for all you do on this podcast to make us aware and educate us!

[colden]

Listening to Gary Brecka motivates me to be a healthier individual.

[MichaelBrown-pltv]

I started your protocol in September 2023. Currently I’ve lost 40lbs! I feel amazing!
Thank you, Thank you! 🙏🏽 😊

[greyfi]

Sir, truly appreciate the candid discussion. My wife is a 57 year old former Marine who was exposed to the toxic water at Camp Lejune, NC in the mid 1980s. Prior to her exposure she was healthy and energetic. Subsequently her health has been deteriorating. Specifically in terms of suffering a miscarriage, uterine fibroids and a full hysterectomy among other things. Most of the medical professionals we've consulted over the years attribute her declining health to the aging process. I vehemently disagree with their assessment and their lack of curiosity about how her exposure may be a causative factor. To date she has undergone a myriad of standard blood tests and diagnostic imaging in order to determine the root cause(s) of her ailments. Unfortunately we are still in the dark and nowhere closer to understanding the underlying cause(s). As a result she's resorted to self medicating with over-the-counter vitamins and herbs. In my opinion this is a less than optimal approach considering we don't know what, if any vitamin deficiencies exist. Not only that but she could be doing more harm than good. My current goal is for her to seek a holistic - rather than a myopic health assessment taking into account her age, family history, lifestyle etc. in order to connect the dots. I'm cautiously optimistic your approach to health and longevity may warrant a consultation. Please contact me if you feel you can help us.

Thanks and Semper Fi
Ken

[Missashleycahill]

I’m so glad I found you. I suffer with adhd, fibromyalgia, insomnia, I’ve had cancer, I have high blood pressure but the one thing I’m terrified of the most is getting dementia. Both my parents had dementia and I do not want it!!! I’m going to do all the things you say and recommend. Thank you so much!! ❤

[DianeBenedetto]

Gary I can't even begin to thank you for all your knowledge. I have been religious watching all your pod casts retrieving your information on the genetic testing, morning rituals and everything else you have said. I feel so blessed and I know that someday I am going to meet you in person! and give you the biggest huge ever!! Thank you for all you do and may the Lord continue to bless you.🙏

[joan]

I started methyl folate and selenium in 2018, I had a brain tumor. Btw: my experience during and after was balanced. I eat well but 5 surgeries and 13 months of chemo was not the shit show you hear about. My numbers jumped back and, it was damn miracle and I got strong and did not go into a crazy mental or physical health spin. I will always take methyl-vitamins every day. No mental imbalances to speak of and I have a very demanding job to boot.

[livmorefit]

Our body is designed to heal itself when given the proper things😀

[aojorel]

Just listening to the opening of this man let me know that he is a phenomenal human that he felt guilty for his line of work. And then on top of that he is blessed with a wife that was very supportive of his dreams. That doesn’t really happen too often anymore especially here in the west.

[Adanacon]

Since taking Methylated B complex and TMG.

My skin is amazingly healthy. I’m a carpenter and typically have dry, cracking, bleeding hands. My hands are in perfect shape! My nails and cuticles look the healthiest they’ve ever been.
My joint pain is dramatically less and my anxiety has been significantly reduced as well.