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Lecture 5a: B Cell Development
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UCSD Extension School: Applied Immunology (BIOL-40371)
Spring Quarter 2021
This lecture presents a summary of the selection mechanisms imposed on immature B cells in the bone marrow and spleen, and how these selection mechanisms yield a mature BCR repertoire that can be used to defend the host from infection while preserving both central and peripheral tolerance.
All figures are either from Janeway's Immunobiology (9th ed.) where noted, or my own original figures.
Spring Quarter 2021
This lecture presents a summary of the selection mechanisms imposed on immature B cells in the bone marrow and spleen, and how these selection mechanisms yield a mature BCR repertoire that can be used to defend the host from infection while preserving both central and peripheral tolerance.
All figures are either from Janeway's Immunobiology (9th ed.) where noted, or my own original figures.
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