New Science of Muscle Hypertrophy - Part 1, Physiology: 55 Min Phys

For all of you muscle nerds out there, I cover the latest science on:

1. How much muscle grows
2. Is the growth uniform across the muscle?
3. Show you ACTUAL elite athlete muscle fibers
4. Sliding filament theory
5. Myofiber lengthening
6. Myofiber splitting & hyperplasia
7. Myofiber growth
8. Bodybuilder vs. powerlifter muscle growth
9. Sarcoplasmic hypertrophy
10. Include a special challenge.....

In Part 2 of this 3 Part series, I'll cover "What & How To Cause Muscle Hypertrophy".



◾ Instagram: @drandygalpin

◾ Twitter: @drandygalpin

[hubermanlab]

What an impressively thorough and mechanistic description this video is!

[PrimeMatt]

An 81 minute, "55 minute" tutorial, maybe there is some good in the universe? 🙌🏼

[mattreinecke]

Hello from Italy! Starting to watch your older stuff after seeing you around at all the top podcasts.

Everything is so well explained. This is a wonderful resource.

One correction. While his paper was in German, Morpurgo was Italian. He was a professor at the Università di Siena.

[Lane_Narrows]

Love your long form videos. I'm and exercise phys grad student and I listen to your videos on repeat while I'm riding the indoor trainer.

[billytheweasel]

People that skipped vid one shorted themselves. This is exactly what I've been searching out for 8 years.

I wish YT had suggested this channel long ago. It took Dr Huberman's tip who also should have been suggest to me on his 1st vid.

[adamcatto]

There wasn’t a ton of *space* in between all the great explanations to make that *needle* joke, but I’m glad a Washington guy like yourself was able to make room for it

[ryanfollweiler]

My brain is exhausted, but awesome video!!! I’m a little confused with what proteins are growing if contractile fibers are not growing. I’ll have to rewatch

[Masleus]

Andrew Huberman and Costello brought me here. Thank you, Dr. Galpin, for your work.

[coachpaul-vedicfitness]

Thank you from the bottom of my heart for taking the time to make such well done educational videos Andy.

[justinmabe]

Great work! I am going to share this with the students at my institution. You explained everything in far greater depth than I ever could and with better visuals!

[philippjochem]

Thank you very much, Dr. Andy Galpin, for sharing this valuable knowledge.

[marketissupreme]

When watching other YouTubers video: I watched 3 min out of 10
But for Andy's video, I can't skip a beat. Love from India man, the way you explain is brilliant🔥

[bluntforcetanya]

Omgggg seeing the actual fibers outside the body was so cool!!!!

[pickyvanilla]

This is so helpful!

Thank you so much for sharing knowledge! 😊

[Persepolis]

Your channel should have millions of subscribers

[edmundomiranda]

Thank you for providing complex scientific knowledge on muscle physiology in a more graphical, illustrated, and simplified way. One comment and question: Satellite cells are stem cells so that they can become new muscle fibers (adding new cells, aka hyperplasia), so that it appears that, to some extend, under damage or injury of muscle fibers there is hyperplasia (a place we do not want to get under optimal progressive loads), so that an hypothesis could be that hyperplasia of muscle fibers is restricted as a mechanism of tissue repair from significant damage or injury. However, is valid to distinguish between new muscle fibers from satellite cells versus mitosis of actual muscle fibers. ;-)

[ekiboi]

Holy smokes, this was a brilliant video! Just recently found your channel via my friend who shared this video, at the first glimpse your channel's content looks great! As an enthusiastic exercise physiology science reader and coach there was a lot new things and studies I learned through this and above them all, new info about muscle fiber hyperplasia, real thing or not. I've always used term muscle hypertrophy a lot, but haven't really known all the things it holds inside. So this really widened my view and next I'll head to those referenced studies and your other videos. Thank you!!

[daliborpetkovic]

Svaka čast majstore, world needs more people like Andy

[fabio]

First of all thank you for this amazing video, amazing content and always for free.
What impressed me most about all of this, is to finally know the truth about hyperplasia, fiber splitting etc. and then also to see it in a different point of view, that is the myofibular way. That's whats impressed me most, going through all levels from macroscopic to ultrastructural and trying to see whats is happening there and to know from where does hypertrophy come. I'm looking forward to jumping to the other videos thanks Andy :))

[KarenWinna]

Andy, your videos are incredible, I’ve been learning so much from you! I wish it was a live class so I could ask the millions of questions and thoughts I had!
Here goes one: If heavy load hypertrophies myofibrils, resulting in the increase of their diameter and potentially more contractile, which would technically result in greater strength, how come some people are really strong but not big in size at all? The opposite may be explained by the sarcoplasmic hypertrophy but what about the opposite? Purely neurological adaptations? Thanks and looking forward to videos # 2 and