Electron transport chain

Harvard Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance.


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[LavenderTheArj]

I remember when I was studying biochemistry II in my bachelor's degree, desperately looking for a video on this on the night before the final exam, didn't find one and had to memorize it the old fashioned way, all I'm saying is that what you're doing is extremely valuable for a lot of students, best of luck.

Imagine a whole biochemistry book animated like this... I wish I'd be alive till then :'(

[nickmagrick]

the visual explanation really helps a lot.

[noelsrx]

This is physics, chemistry and biology combined in one! And I love it!!

[Roger-gojc]

This is just awesome. I'm 69 now and still doing paediatric nursing, but started my career in Pathology. I remember pawing through my Biochemistry text to sit exams and trying to memorise the Krebs Cycle, which is all part of this. But the process I did on a page that showed chemical energy utilised for cellular respiration has just blown right off the page. This visual takes me into a Mitochondria and starts to put the cycle into a visual sense. What a wonderful progression in knowledge we have.
Now lets not forget who we are and what a beautiful planet we have.

[hasen_judi]

"and this is why we have to breath oxygen" was a mind blowing moment for me.

[killianoshaughnessy]

I am amazed at the complexity of being alive.

[hosoiarchives]

0:29 inner mitochondrial membrane
0:47 key role is to separate protons, inner from outer protons
1:08 ATP synthase, makes ATP. Uses proton flow to work
2:24 Complexes 1, 3 and 4 pump protons out
2:49 complexes get energy from electrons
3:18 complex 1 uses NADH and reduces it

[lilyilyily]

RIP prof lue, this video is just one of many thousands of wonderfully helpful, selfless things he contributed to the world during his too-short lifetime.

[Lisargarza]

Learned all this stuff in grad school 40 years ago, but it was more like a concept, a chemical formula written on a page. To see it spring to life as an animated video is astounding. Thanks for posting.

[aryansaeedi]

My god what a beautiful video. Very clear and well explained. I’m in love with this channel.

[vedantbhardwaj]

I'm a medical student at King's College London, and honestly this has helped me sooo much with actually being able to visualise how Oxidative Respiration actually occurs!

[makaylamoore]

Such a great, clear explanation! Videos like this remind me why I love biology so much. Life is amazing.

[Roninz]

The animation was incredibly helpful in understanding the material. My mind tends to wander during lessons so the visual aspect was immensely helpful.

[yvonnemoreno]

This is amazing. It puts all these concepts we're inundated with and makes it more clear. As a visual learner, I wish there were more animated videos like this!

[Darkmatter]

This happens a few Trillion times a second in our bodies. No big deal!

[lucachirico]

I watched this video 3 years ago for the First time, when I was studying biochemistry for the exam of the bacheloor degree. Now I've just re-watched it to review the topic at all for work, and it's gorgeous like ever. I think immagines and videos can teach better then thousand of a book's pages. Colours and animations are for me the best way to rember and put every feature in our brain.

[jayski]

I wish we could have had visualizations like this back when I was a pre-med student in the 1970's. All we had were acronyms, arrows, and line drawings. The best analogy I can come up with is a wrist watch - in my day we could look at the watch face but just read about what made the hands go around; this animation is like opening up the back of the watch and finally seeing all the gears and springs in action.

[raplopez]

What makes this video stand out is not just the breaks, but the respect for the student, BY GIVING US 5-30 SECOND BREAKS TO JUST RELAX THE BRAIN!!!! (*Cough to all you other science videos/teachers out there cough cough*)

[geofractal]

This is incredibly amazing. It is also amazing that humans can figure this out -- very smart humans, that is.