Stimulating Skeletal Muscle Protein Synthesis

Stimulating Skeletal Muscle Protein Synthesis: Is the Quality of Isolated Protein Important When It Is Ingested with Other Nutrients?

Organised by Francis Stephens, University of Exeter, UK and Kostas Tsintzas, University of Nottingham, UK

Dietary protein consumption stimulates skeletal muscle protein synthesis (MPS) and inhibits muscle protein breakdown. It is generally assumed that the anabolic potential of a dietary protein is dictated by its amino acid composition, particularly leucine, as well as digestion and amino acid absorption kinetics. However, an emerging concept in recent literature is that nutritional factors beyond amino acid bioavailability are important for stimulating MPS, particularly as plasma leucine concentrations are less predictive of subsequent MPS in studies where protein is coingested with other macro- and micro-nutrients. During this webinar, two speakers discussed the concept of the whole food matrix and the relative importance of various macro- and micro-nutrients for stimulating MPS.

[serbianboss]

Conclusion - eat whole food animal based meals (eggs, milk, meat)!

[Bungifun]

It shouldn't be too complicated to understand that in order to grow muscle you need to grow the number of cells. Growing cells doesn't just need protein. You need membranes for the cell and its organelles which requires cholesterol and fatty acids. You need vitamin and minerals as co-factors to support the grow process itself such as for example zinc. So when you want to similar MPS, all of it needs to be sufficiently available or they could become a reducing factor from what is maximally possible

[noonalinour]

Would MPS still occur with low amount of Leucine less than the threshold?

[DLife]

So if I weigh 100kg I "m maxed at 30 g protein a meal ? or may I go up to 40 grams . meal ?

[stevengraham]

I really, really want to understand you but the first lecturer uses vocab that is never defined and combination of words that our just outside my knowledge base. It's too bad because it sounds helpful but your talking to doctors. Perhaps that's your target audience, but explaining what are leucine, "overtake a protein plate, " even what it means that proteins are "adaptable, " etc. and slow down to give us interested laymen and women can track ...it would be soo much more helpful and I for one would be able to put your wide knowledge base to use.