Vitamin D and pandemic science

US, NHI Guidelines

About 42% of the US population is vitamin D deficient

82% in black people

70% in Hispanics

Public health England

Vitamin D dose

IU mcg
400 10mcg
800 20mcg
1,000 25mcg
2,000 50mcg
4,000 100mcg
6,000 150 mcg

Facial Masking for Covid-19 — Potential for “Variolation” as We Await a Vaccine (NEJM, 14th September)

Universal mask wearing might make mild or asymptomatic disease more likely

A form of “variolation”

Inoculation

Generate immunity and thereby slow the spread of the virus

Viral shedding from the noses and mouths of patients, presymptomatic or asymptomatic

Shedding rates equivalent to those among symptomatic patients

SARS -1

A strong relationship between public masking and pandemic control

SARS - CoV - 2

Recent virologic, epidemiologic, and ecologic data

Hypothesis that facial masking may also reduce the severity of disease among people who
do become infected

Long-standing theory of viral pathogenesis

Severity of disease is proportionate to the viral inoculum received

Typical rate of asymptomatic infection, estimated to be 40% by the CDC in mid-July,

Settings with universal facial masking, 80%

Also less severe and less deaths

Tiny Antibody Component Highly Effective Against COVID-19

Ab8 evidence of efficacy in vitro and animals

Monoclonal antibodies to begin UK trial

n = 2,000

2,000 more needed (me)

UK Recovery Trial

Neutralising antibodies

REGN-COV2 will be a new arm of the trial

Mixture of two monoclonal antibodies

US biotech company Regeneron

Regeneron, monoclonal antibodies, Ebola

Both attach to the spike of the virus at slightly different places

PFIZER/BIONTECH VACCINE

Albert Bourla, (CEO of Pfizer)

Making good progress with a COVID vaccine

60 per cent chance, will know by the end of October their vaccine was effective and safe

Trials have been carried out on 30,000 people, and that is expanding to 44,000

Then move on to FDA to certify

Already had 'hundreds of thousands' of doses ready to go

Mass manufacture in hand

UAE approves urgent use of China-developed COVID-19 vaccine after test on 31,000 volunteers

Phase I and II results June

100 percent of volunteers generating antibodies after two doses in 28 days

6 weeks, 31,000 volunteers, 125 nationalities, phase 3 started 16th July

United Arab Emirates (UAE) emergency approval for use

China National Pharmaceutical Group (Sinopharm)

Department of Health of Abu Dhabi

Clinical trials, simultaneous in Bahrain, Jordan and Egypt

100,000 injections given so far, no adverse reactions, no infections

Mild and expected side effects

No severe side effects or complications

Volunteers, 1,000, chronic diseases

Volunteers now receiving their second shot

AI and supercomputing, trial results, fast

India

May fast track vaccine

[redd]

I personnally have been taking 6000 IU of Vitamin D since I begun listening to you Dr. John. The results are nothing short of remarkable. First of all my immunity is working much better, my low level inflammation has basically vanished, and my muscles feel much more flexible. But the biggest difference is with my mental health as I find it much easier to relax and letting go of my anxiety. Of course I know that this is anecdotal evidence, but for me it has made a real difference.

[peabody]

I personally take 5, 000IU a day and recent doc had a checkup with a blood test and asked them to check my vitamin D level, well I'm happy to report doc said they were awesome and right where it needs to be.

[elaineallinson]

My first daughter was born in 1968 (52 years ago). At that time, when I went to the baby clinic, I was given a small dropper bottle of Vitamins A&D. This was added ( a few drops a day) to the baby formula as standard. They obviously knew 52 years ago that Vitamin D was important to us all.

[garywright]

This has become a daily must see viewing for me since I came across it about a month ago. I have leaned so much more from your daily vlogs than I would have from mainstream media. Everybody needs to watch these. I feel so much more optimistic and informed. Thanks for all your hard work John, and the excellent way you put the information across.

[ooassel]

I love you for addressing this topic. My wife has been diagnosed with Multiple Sclerosis and has suffered permanent damage from it, but the disease has been in remission for three years since she was treated with high doses of vitamin D according to the #coimbraprotocol This substance is extremely important and no one should be deficient to prevent permanent damage.

[elainemagson]

So soothing. He never patronises his listeners but he does make it all easy to understand.

[catherinenelson]

Thank you Dr. John, and thank you, Mrs. Campbell for your behind the scenes support. Things like Dr. John's vitamin D recommendations do get talked about. Word if mouth spreads the good information. So more people are benefitting than just those of us who are watching the videos. 😊🤗😼🌍🌎🌏🚸

[primordialmeow]

Thnx. RN here. 66 yo. Euro. Raised near Canada border. Started out at very low D3. Have slipped into osteo arthritis. Now taking 50, 000 IU D3 per week per Rx. Recent lab up to 41...this took three years. Happy with this. Keep vigilant. ❤

[kotenoklelu]

I started to take vitamin D because of coronavirus craze (I know it's serious illness but I am tired from lockdown). I take little doze as on the instruction. And I was surprised but my depression ended. I live in the north, in Siberia, and I guess vitamin D deficiency is widespread here. My mom broke her arm, her bones are easily brokebele because of vitamin D deficiency. Thanks, doctor

[retiredminimalist]

Who'd believe an obscure doctor from the north of England would become my personal hero?

[superNowornever]

I'm a 56 yo fairly light skinned female living in northern NY state (think dark, cold and 125 inches of snow yearly :p). My doctor tests all patients annually for vitamin D levels because deficiency is so common here. My levels have typically come back at the low end of the normal range, probably because I eat eggs and fish daily, but after starting 2000 IU daily, a couple years ago (take it in the morning) my vitamin D levels have been great, and I believe I get fewer of the winter viruses that float around here....

[untouchablex]

"Winter is Coming." John of the House Campbell. First of his name...

[christianwarrior]

I've been taking vitamin D (125 mcg), since you first stated.... husband and I have not been sick. Thank you for all your hard work.

[stephennixey]

I take 2000IU per day in the summer and 3000IU in Winter and have done for 10 years and have not had a cold of flu since, I also walk out every day and walk about 20 miles minimum a week.

I used to suffer 1 or 2 colds per year and 1 Flu effect every couple of years, I had SARS-CoV1 back in 2003 which I caught in China town London!

We need to get our blood levels up to 40ng/ml (30ng/ml minimum) and checking blood levels are best carried out in the winter months when D is low.

[christianfrancois]

My hat off to you for being honest and courageous in speaking out.

[emb]

The reason they didn’t encourage mask wearing early on was because they didn’t have a good supply and needed the masks for medical folks. So of course that was completely contradictory. But instead they should have been saying immediately that masks would be helpful, but in order to save them for our medical staff- make your own.

[ruairidhalexander]

"go to your doctor and get a test for vitamin d levels"
Have you tried going to see a gp recently? There's no way they would let you anywhere near the gp surgery for something like a vitamin d levels test in the current pandemic situation.

[dionysus]

I always stay to the end, Dr John. The information is interesting and fascinating. Thank you! 👍

[jaynecooper]

Thank you for pulling this together Dr John. Please can we have some info on the need to take vitamin K2 with D3? Keep safe and well. Jayne. 🙏💖🙏

[lludwick]

Great work Dr. John Campbell!
My doctor has had me on V-D3 for 3 years. He is much like you in kindness and knowledge on a personal level!