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Gut Microbiota and Mood: Can you eat your way to happiness?
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This video discusses recent discoveries that reveal a link between gut microbial composition and mood disorders. It outlines the role of serotonin in the body and discusses a set of studies that test the role of gut bacteria in regulating human mood. This video also discusses the limitations in the scientific literature, future directions, and the potential use of bacteria in mood disorder treatment.
This video was made by McMaster students Hani Fakhri, Sabhat Khan, and Pukhraj Gaheer in collaboration with the McMaster Demystifying Medicine Program.
This video is provided for general and educational information only. Please consult your health care provider for information about your health
Copyright McMaster University 2022
#DemystifyingMedicine #MentalHealth
References:
Aizawa E, Tsuji H, Asahara T, Takahashi T, Teraishi T, Yoshida S, et al. Possible association of bifidobacterium and lactobacillus in the gut microbiota of patients with major depressive disorder. Journal of Affective Disorders. 2016;202:254–7.
Cheng L-H, Liu Y-W, Wu C-C, Wang S, Tsai Y-C. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. Journal of Food and Drug Analysis. 2019;27(3):632–48.
Fung TC, Vuong HE, Luna CD, Pronovost GN, Aleksandrova AA, Riley NG, et al. Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut. Nature Microbiology. 2019;4(12):2064–73.
Huang T-T, Lai J-B, Du Y-L, Xu Y, Ruan L-M, Hu S-H. Current understanding of gut microbiota in mood disorders: An update of human studies. Frontiers in Genetics. 2019;10.
Li N, Wang Q, Wang Y, Sun A, Lin Y, Jin Y, et al. Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis. Stress. 2019;22(5):592–602.
Slykerman RF, Hood F, Wickens K, Thompson JMD, Barthow C, Murphy R, et al. Effect of lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine. 2017;24:159–65.
This video was made by McMaster students Hani Fakhri, Sabhat Khan, and Pukhraj Gaheer in collaboration with the McMaster Demystifying Medicine Program.
This video is provided for general and educational information only. Please consult your health care provider for information about your health
Copyright McMaster University 2022
#DemystifyingMedicine #MentalHealth
References:
Aizawa E, Tsuji H, Asahara T, Takahashi T, Teraishi T, Yoshida S, et al. Possible association of bifidobacterium and lactobacillus in the gut microbiota of patients with major depressive disorder. Journal of Affective Disorders. 2016;202:254–7.
Cheng L-H, Liu Y-W, Wu C-C, Wang S, Tsai Y-C. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. Journal of Food and Drug Analysis. 2019;27(3):632–48.
Fung TC, Vuong HE, Luna CD, Pronovost GN, Aleksandrova AA, Riley NG, et al. Intestinal serotonin and fluoxetine exposure modulate bacterial colonization in the gut. Nature Microbiology. 2019;4(12):2064–73.
Huang T-T, Lai J-B, Du Y-L, Xu Y, Ruan L-M, Hu S-H. Current understanding of gut microbiota in mood disorders: An update of human studies. Frontiers in Genetics. 2019;10.
Li N, Wang Q, Wang Y, Sun A, Lin Y, Jin Y, et al. Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis. Stress. 2019;22(5):592–602.
Slykerman RF, Hood F, Wickens K, Thompson JMD, Barthow C, Murphy R, et al. Effect of lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: A randomised double-blind placebo-controlled trial. EBioMedicine. 2017;24:159–65.
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