The Gut-Brain Connection

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Duke University researcher Diego Bohorquez and colleagues have identified the neural circuitry that connects the gut with the brain. This pathway is spanned by a single synapse, capable of relaying a signal from gut to brain in 100 milliseconds. This newly discovered pathway is probably exploited by pathogens, and will almost certainly lead to new therapies.

𝐀𝐛𝐨𝐮𝐭 𝐁𝐨𝐡𝐨𝐫𝐪𝐮𝐞𝐳 𝐋𝐚𝐛
The ambition of Bohorquez Lab is to learn how to treat the brain from the gut. Researchers are focused on dissecting the neural circuits that transform signals from food and/or bacteria in the gut into electrical inputs that modulate behaviors like the desire to eat. The laboratory is built on multidisciplinary expertise in viral vector genomics, neurophysiology, behavioral phenotyping, organoid cultures, and neuroimaging. From human miniguts to its own 2Photon –The Wraith– Bohorquez Lab has the pipeline optimized to test ideas from single cells to whole animal behavior.

𝐀𝐛𝐨𝐮𝐭 𝐃𝐮𝐤𝐞 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
Established in 1924 in Durham, North Carolina, Duke University is one of the world’s leading institutions for education, research, and patient care.

𝐅𝐨𝐥𝐥𝐨𝐰 #𝐃𝐮𝐤𝐞𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲
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I had horrendous depression for 10 years. Zoloft did not work. I traced it to foods I was eating (milk, eggs, sunflower seeds, turkey), which gave me severe depression for three days. Sunflower seeds gave me depression and severe, diffuse back pains. One day I had a nasty sinus infection that felt like heart failure. I couldn't catch my breath and felt tightness in my chest. But I was aware that my sinuses felt slightly sore. It took three different powerful antibiotics to get rid of the infection. Then I dared eat foods that gave me depression. It was gone! Three years later and I haven't had any depression. Unfortunately, the experience was traumatizing and I have some PTSD. Just the thought of that severe depression terrifies me. I don't talk about it to anyone directly.

marylamb
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So important considering that your gut microbiome impacts everything from your immune system to your skin to your brain function to your digestion, and even your mood and mental health!! 👊✨

getwellbe
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The imagery on this video are fantastic! Fascinating video, and it really does show how the brain and gut are interconnected. When people have depression and/or anxiety, they really should look at their gut health. Thanks for sharing!

DrJanelleSinclair
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Who ever dislike this video probably doesn't have a healthy gut.

tinacudal
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This video is very short but informative. I have heard of the gut to brain connection in the past but never read up or researched it. However, after watching this video, I am definately going to watch/read more about this subject. Definately recommend this video. Give it a go only 2 minutes of your life.

elainer
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Simply wow, human body and its functioning is fascinating, it's like a universe, mysterious

gayathrich
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This makes a lot of sense that the gut and brain are connected. I mean your gut needs to tell your brain if you're full, sick, eating, hungry, etc. It makes sense that sometimes this connection can go haywire sometimes, since it's constantly communicating with the brain.

fundifferent
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The most helpful biology information I've come across only in two minutes.

intelligentdesign
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Colostrum is one of the best things for the gut-brain axis. It heals leaky gut in no time.

Shurmash
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I always heard that "your gut is your second brain" and now I finally got why x)

lunajz-
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A 1/2 tsp of natural salt will can ease that heavy upper gut feeling that is connected with depression. Mix it in water and chug. The world has trained everyone to be afraid of salt but good natural salt 🧂 has health benefits it you don't overdo it. Anyway, it has helped my gut depression a lot. Also apple sauce with a splash of apple cider vinegar 🍎 🍏.

hopewins
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Absolutely well done and definitely keep it up!!! 👍👍👍👍👍

brainstormingsharing
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You following your gut is what led you here

hohnjopkins
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Could this be possible cause for anxiety?

Ace-tckm
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Eat fermented food for good bacteria...good bacteria is key for a healthy gut biome. Refrigerated sauerkraut, Kimchi(Korean cabbage), plain non-fat Greek yogurt with live and active cultures...stay away from sugary yogurts...and a teaspoon of Apple cider vinegar a day...also eat lots of dark greens to feed the healthy bacteria..including seaweed..

Buckeye__Life_
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Is that why I feel so happy when I eat delicious food and my stomach is full?

gerardog
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Look how complete the human body is and how sophisticated it is. It is hard to watch this and still conclude we evolved without God creating us.

BiDrd
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We have a second brain in our gut—the enteric nervous system (ENS) with over 100 million brain cells. 💕 ☮ 🌎 🌌

totalfreedom
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I was facing nervousness problem, and my stomach area was palpitating like heart, so I thought what is the relation between gut and nervous system

samsyes
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One of those cells is not like the others!

HoganR