Can You Get Rid of Fat Cells? Weird Science!

Can You Get Rid of Fat Cells? Weird Science! - Thomas DeLauer

A study published in Nature found that the number of fat cells you have remains fairly constant throughout your life, regardless of whether or not you diet, or are thin or fat

From infancy to our early 20s, the number of fat cells in our bodies increase - once we hit our mid-20s, though, we maintain the number of fat cells we have (fat cell numbers level off and stabilize in adulthood)

*Overweight people tend to have more fat cells than slim people*

Though some cells may die, our bodies are quick to replace them - as if we’re programmed, to have a certain number of fat cells

Cell death and production appear to be tightly coupled, so although about 10% of adipocytes die each year, they’re replaced at the same rate

So the number of fat cells stays constant in adulthood in lean and obese and even under extreme conditions - when fat cells die, like all cells do, the body simply creates new ones in its effort to keep the number constant

Neither adipocyte death nor generation rate is altered in obesity, suggesting a tight regulation of fat cell number that is independent of metabolic profile in adulthood

**The catch here is that some people are “born” with more fat cells, and others have less. Just like how some people are taller or shorter than others.**

Resistance Training - Study

Researchers examined the effects of resistance training (RT) frequency performed 3 times per week (RT3) vs. RT performed 6 times per week (RT6) under volume-equated conditions in resistance-trained men

27 men were randomly allocated to RT3 (n = 14) or RT6 (n = 13) - the supervised training intervention lasted for 6 weeks

Pre-to-post intervention, both groups increased upper-body strength (RT3: +4%; RT6: +6%) and lower-body strength (RT3: +22%; RT6: +18%) with no significant between-group differences

Both groups increased elbow extensor thickness (RT3: +14%; RT6: +11%), rectus femoris thickness (RT3: +5%; RT6: +6%), and vastus intermedius thickness (RT3: +10%; RT6: +11%)

Concluded that when training volume is equated, it seems that RT performed either 3 or 6 times per week can result in similar strength gains over a 6-week training period

Furthermore, under volume-equated conditions, comparable hypertrophy results may also be expected with both RT frequencies

Keto & RMR - Study

A study published in the journal Nutrition & Metabolism looked to see keto’s effect on permanent weight loss via its effects on RMR

Researchers chose a set of 20 obese patients who followed a low-calorie keto diet in order to induce weight loss (was pretty low calorie; 600-800 kcal) - the subjects lost around 45 lbs each over the course of 4 months

But what they found was that despite the patients’ large weight loss, that weight loss didn’t affect the patients’ RMRs in any significant way - there was no significant differences in their basal RMR and no metabolic adaptations occurred

Researchers concluded that the absent reduction in RMR was not due to increased sympathetic tone, as thyroid hormones, catecholamines, and leptin were reduced at any visit from baseline

The researchers concluded that because the study participants didn’t lose a lot of muscle mass, their RMRs stayed steady and so did the weight loss

The rapid and sustained weight and FM loss induced by VLCK-diet in obese subjects did not induce the expected reduction in RMR, and was concluded that this outcome was likely due to the preservation of lean mass that keto offers

*Ketone bodies exert a restraining influence on muscle protein breakdown - if the muscle is plentifully supplied with other substrates for oxidation (such as fatty acids and ketone bodies, in this case), then the oxidation of muscle protein-derived amino acids is suppressed*

[austincooper]

This was super cool. This is the kind of information from you that I live for Thomas. 😁

[usahome]

“The good vitamins get quarantined inside the fat.”

You are ahead of your time, Thomas.😂

[KrakatoaEdd]

I'd love to know more about my situations, I'm overweight 90kg/173cm , currently into fasting, started about a week ago.
Knowing why things happen and how to work with not against my body makes me feel more in control. So yes pls do keep up with this branch!

[nicklandreth]

I have always wondered does liposuction get rid of fat cells?

[valentinek]

Thank you for this information it helped me understand just what I have struggled with for 45+ years. I know that this has noting to do with the topic of today, but it is always great to see when you add snippets your wife and child because it is encouraging to see a family man talking about this things, it makes it so the rest of us family guys can actually relate to you better, just my opinion.

[chrishellize]

This has cheered me up and got me enthusiastic again. I have recently started keto, after fasting 16 to 21 hours every day for 7 months and not losing any weight at all. Thanks to your videos I will now mix my fasting schedule up a little, keep with keto and add resistance exercise as well. As soon as my broken shoulder heals! Thank you, you are a genuine help.

[michaelcudd]

This video made me less depressed. I watched a video before this how it was all over if you get fat. Appreciate the motivation to keep pushing!

[TheNaSTyWoRM]

So true man, I have not been the one to be over weight but I constantly used to cardio, cardio, cardio. Never understood why my mid section never burnt any fat. Well i started my keto journey a month ago today lost significant weight and started conducting weight training instead of just cardio and I am finally shrinking in the mid section! Love the knowledge you drop on us weekly brother. Keep it up!

[lifeisagift]

I wish I can gain muscles the same way I gain fat 😂😂😂

[TrevorMcGheeComedy]

Once again great video! Thanks so much! Can't wait to meet you one day man, you've helped me so much! Lost 75lbs in 4 months just from your science breakdowns and you explaining things so i can actually understand your vids. I think I'll try on Keto soon! And that was just from eating right! Gonna add weight lifting and exercise now so fired up! Thanks Thomas you da man!😁💪

[stephaneouellette]

Thomas i love how you go through details and explain everything about what you put up on Youtube.Your videos are very well done.

[donnaeisloeffel]

Only bigger people understand how much I love you right now!!!!
Back to the gym

[kellykaepernick]

When I went on my first weight loss journey and lost 70 lbs...I was a chick afraid of the weight room and a trainer told me go to the weight room and do not be afraid of lifting you will lean out and not look muscular. He was so right. Now I'm on my second and last journey and losing 50 again...back in the weight room now. 🤗

[swaidy]

Loved it man. This is exactly the kind of stuff I follow you for. Keep it coming.

[joedaugherty]

Great motivator video bro, happy 4th of July to you and your family

[BarrierSecurity]

I finally found this very intelligent person and video on weight loss. Great job; fantastic, actually. Well explained. Inspiring. Will see more of your videos asap.

[alexbedminster]

Such a great channel. Thomas thanks for your hard work and spreading the findings and education to the community. I always relay this information to my wife and we try and apply and grow in our knowledge of what we eat, how we train and how we fast!
Just giving some love dude!

[wolfwarrior]

This info was completely new to me. Thank you Thomas.

[MPARKS]

Great video. Excellent information delivery. A lot of stuff I didn’t even know; I wanted to know.

[pablo]

More fat cells means more potential to build muscle. Niiice. I think I’ve actually noticed that with powerlifting etc over the years