Dosing and safety of Methylene Blue

There is a lot of confusion about the dosing of methylene blue for brain health and optimal cellular function.  This video discusses dosing of oral methylene blue as well risks and side effects. 

#methyleneblue #supplements #mitochondrialhealth

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If we haven’t met before - Hey 👋 I’m Jonas, a primary care MD - turned preventive healthcare educator. I started this channel to help people make decisions in many aspects of day-to-day living that can significantly impact their health.
Many of the topics discussed here arise from questions my patients and subscribers ask me.

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[ToWhateverEnd]

I had a genetics testing panel which showed a mutation for Mitochondrial I Complex process. I began taking MB about 1 year ago, 30mg daily. Lifelong dark circles under my eyes cleared up, my skin health improved vastly and I no longer feel fatigued by early afternoon or evenings. I also tapered off of an SNRI and feel MB is a very natural antidepressant (at least for me). I will continue taking it as I also have APOE Alzheimer’s risks.

[christinasportiello]

Awesome!!! Yup I was confused for this reason.

[jordanmetlikovec]

Very good information. Clear, concise and to the point. Helps a lot. Thanks.

[vetteluvnh]

Very informative. Thank you for the clarification on dosing.

[RA]

This is exactly the video & information I was looking doc.

[mariavictoria]

Excellent info and very comprehensive, thanks and I subscribed 🙂

[conservative-kulz]

Awesome information Doctor. Very much appreciated. Thank you so much for clarifying so much confusion on this topic.

[JackDisturber]

I've been taking about 20-30mg daily for month or bit more (in split doses, restored by ascorbic acid), which is 0.25mg/kg to 0.38mg/kg in my case and after that did a 4 day water fast and I actually noticed that urine was colored green until the very end of 4th day. So seemingly it did accumulate over time and I'll need to tune down the dosage. I've actually seen something similar in literature when they proposed that color may be indicative of patient oxidative status (the darker urine gets, the more oxidative stress there is), but I also think that taking pauses can help figure out individual dose. Thanks for the vid, was one reason I considered reducing the intake

[yavor_zlatanov]

Best explanation on how to dose methylene blue I was able to find on Youtube, as well as other clarifications which were not elaborated in other very informative and lengthy videos -- thank you, Doc!
Subscribed!

[larry]

Thanks, the sleep disturbances I've had have been crazy nightmares, so now make sure I take last dose way earlier in the day

[victorpinheiro]

Good information Dr Jonas. I started taking MB, 35mg daily, yesterday for sarcoma cancer. Thank you for your posts!

[fourthtunz]

I started taking methylene Blue about five days ago, mainly for energy and for arthritis pain. I feel as of today it’s been helping and after dinner it seems like the pain was back and my energy had dipped so I’m glad you mentioned the half-life. I’ve been taking eighth drops in the morning. I think I may take another another eight in the afternoon now and see how I feel. Thanks for the video.

[EllenStreiff]

If stuck on a deserted island and could only have one health enhancing compound, I would choose Methylene Blue. Micro dosing, 2 days on and 1-2 days off with intermittent longer breaks off, has been most effective. Improved focus, energy, mood, and restful sleep— with no side effects. Overall well being noticeably impacted.

[stevejones]

Thanks for the link. I had no idea where to buy pharmaceutical grade at a reasonable price.

[maryhall]

Thanks, great summary.
Some of the literature discusses drops, others mg.
The leaflet that came with mine stated 1% solution, each drop contains 0.5mg, and instructions to build up to 7 drops (3.5mg). The dosing chart in Mark Sloan's book is helpful.
I wanted to improve mental clarity (im 66) so i now take 14 drops or 7mg, which is enough for me.
Interesting info re: half life and taking a break.
PS, no microbiome issues at all, in fact i would say gut tolerance of grains has improved. I make my own yoghurt with foundation species like L. Reuteri

[buck]

Am I making a mistake??? Excellent information doctor. I have been taking MB in the 10mg/daily range daily. I consume it by mixing it in water with about 1 gram of pure Vitamin C powder. I allow it to sit for a few hours which turns it clear and allows me to drink it without the nasty staining in my mouth.
The information about working out and raising BP did give me pause for thought. I have been using it prior to working out, thinking it would oxygenate my blood and facilitate my workout. I also usually take a far infrared sauna after my workout. It sounds like I may be making a mistake ! I understand you are not giving medical advice or making a medical recommendation. Do you have a general opinion? Thanks again for your great content.

[JulioMacarena]

Vitamin C will neutralise any potentkal stain if you can apply early enough, apparently.

[cosmic]

Thanks for the info doc much appreciated . How long does it take for it to kick in and you will feel the mental effects ? Do you stack it with other compounds to support mitochondria health and function ?

[ScottRiddleArtist]

Do you know if anyone has tried to introduce this into their diet to help fight or manage limes disease?

[healthyanny]

Thank you so much, what dosage for a cancer case?