How Many PRP Injections for Knee Pain?

How many PRP injection for knee pain due to arthritis? I review the most recent medical literature as well as how I’ve adapted our current understanding of PRP and knee arthritis into my clinical practice.

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► ABOUT ME

Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He created a YouTube channel and blog to translate cutting edge medical knowledge and clinical research to benefit all those looking to live an active and healthy lifestyle. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.

Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.

Dr. Peng’s sports medicine clinic is located in Campbell, California.

► Disclaimer

My content reflects my own opinion and does not represent the views or opinions of my employers or hospital systems I am affiliated with. They are meant for educational purposes only. They do not substitute for the medical advice of a physician. Always seek the advice of your physician with any questions you may have regarding your health.

[tgbdxfe]

That is awesome you get the patients input on further PRP's. My MD did the same, the first two PRP's helped, but still not great, . The third injection was life changing, although I still had some pain. The fourth one is making it better. We see definite progress with each new PRP.
So I will continue 4 PRP's a year, every three months, indefinitely . Costing $3, 000 per YEAR. Not much for having no surgery. Thank you!

[djoj]

I have tennis elbow on my right elbow since last year. Had Mri done and found that I had a 3mm tear. Had 3 therapy sensions of 9 times each. 9 rounds of acupuncture and got a cortisone shot in August. I was off work for 6 months. After 2 weeks after the cortisone shot, I went back to work and was feeling great. I took it easy at work, but I started to feel my left elbow starting to get strained a month ago. And now my right both my elbows hurt. I ca n't sleep unless I wear my compression sleeves on both arms. It even hurts to lift my blanket at night.

Just went with my specialist today, and he ordered a prp injection for my right elbow and a mri for the left side. I'm hoping this relives the pain.

[mmnairkochi]

Great video. I had one PRP injection on my right knee back in 2017 and got good relief. Then in 2019 I got one PRP injection on my left knee. Now it is Oct 2023 and I’m still doing well with only very minor pain in my knees after exertion. However, I’m thinking of going back and getting a second PRP injection on both knees as a “booster”.

[DEVanderbiltCecil]

Thank you, Dr. Peng.
This is real hope.

[carolyngurney]

I had my first PRP injection this afternoon after my doctor removed fluid from my knee. It felt better immediately. I will see how the aftermath is. I get another injection next month.

[DocJayWeed]

Thanks for posting. It’s good to hear other physicians treating patients similarly regarding PRP

[bhawanid]

Absolutely fabulous video. Very informative and exactly the way my specialist is providing me PRP treatment. Thank you

[Eva-lipe]

Excellent video. I just need to know the cost. My insurance paid for the 3 series of hyaluronic. I’m scheduled for the single hyaluronic injection soon but after that my next treatment will be PRP.

[rostyslavchaplynskyy]

Very interesting observations! Thank you for the opportunity to get to know the essence of this therapy better! Could you issue a questionnaire to assess the effectiveness of the therapy and the number of injections?

[TheRMcghee]

I have just had my meniscus repaired along with a couple other clean up things on my knee. I am going to try this my insurance doesn't cover PRP. I had PRP done in my shoulder and it helped amazing. I had two injections. My shoulder is bad. Need total replacement. I now am careful and have no pain. Would you say take one and wait and do another. I am not concerned about money! I am thinking about trying Stem Cell. What do you think about the two?

[flyonthe]

Thank you for sharing such important information.

[portcarlingboats]

Can you please speak about 1st generation prp where the platelets are spun for 5 min vs 2nd generation prp where the platelets are spun for 4 hours; what is the benefits of longing spinning time in treatment; thank you Dr. Peng

[bharathsrinivasan]

Great video Doctor. I got 2 PRP injections, the 2nd one at the 3 month mark from the 1st dose. Now I feel good. My pain level have come down and the knee function is gradually improving. My doctor suggested not to go for the 3rd one now, but go for yearly booster more from a prevention perspective.

[chipbyrd]

I greatly appreciate your videos! I have been doing a lot of reading and listening to alternative treatments for knee arthritis. Yours are abundant, clear rest, so thank you. Is there a network of physicians who share your philosophy? I’m looking for someone in West Michigan.

[mohsensafaei]

Hey Jeff. Thanks for the videos. Can you please create a video about cold laser, low light level laser therapy for pain?

[robochen]

Great Video. I've been shopping around for PRP in my area and discovered 1 Dr. Office that warns against some Doctors using PRP kits that provide a lesser, non effective concentration of platelets in their injections. Was curious what your concentration number is and how can we protect ourselves against getting a "watered down" version. ?

[Conorj]

Got a PRP injection w/ hyalruronic acid 3 weeks ago for cartilage lesion/ "chondral defect of lateral trochlea." Was this the right decision? Previously got a PRP injection for partial patellar tendon tear and next MRI showed the tendon healed.
MRI CONCLUSION, 1 month ago before PRP;
-Full-thickness full-thickness chondral defect of the lateral trochlea with subchondral
reactive marrow change of the underlying bone.
-Small knee effusion.
-Tiny Baker cyst

[abuzarinayat]

It will be great if you can share the PRP prep technique and the type of kit you use.

[christopherpritchett]

I do HA injections and I find that at the 4 week follow up, they are still having pain, it's often the Pes Anserine Bursa. A steroid into that Bursa gives instant relief. I've dine a few PRP and will be doing more in the future. Thank you for posting this video.

[khishigeeravjir]

Thanks .
How many times should PRP treatment be done for knee osteoarthritis ?
How many days apart is it good to do it.