Effects of TEA Antioxidants on SARS-CoV-2 Pathogenesis

A Review and Discussion of My Favorite Tea Science Article from November 2021

00:00 - Changes to "This Month in Tea Science" since October 2021
01:00 - Introducing the Topic of 'Tea and SARS-CoV-2'
03:30 - Breaking down the title "Discovery of Camellia sinensis catechins as SARS-CoV-2 3CL protease inhibitors through molecular docking, intra and extra cellular assays"
04:55 - Explaining methodology (selected assays and tea catechins)
07:17 - Results of molecular docking
08:03 - Results of intracellular and extracellular assays
09:08 - Explaining IC50 value, dose-dependency, and bioavailability of tea catechins
11:50 - GCG surprisingly outperforms EGCG in 3CL protease inhibition
14:42 - Wrapping up and summarizing significant findings
15:41 - Implications for future drug development
16:35 - Reiterating the complex nature of this type of research
17:25 - Closing remarks

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Original research article located here:

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Credits:

Outro song by Jared Mulcahy

Turkey image in thumbnail: "Thanksgiving" by Don McCullough is licensed under CC BY-NC 2.0

[TheYashie]

I've been binge-watching this series and binge-learning. This is great, keep making 'em!

[robinredbeard]

Hey Dylan, once again your video brought a question to my head: Why tea? Out of hundreds of thousands of flowering plants, is tea really as singular as it seems to be in terms of health benefits or is it just because comparatively we know this plant so well? Has the world focused its attention on tea because of the caffeine, because we can coax so many flavors from it, both? Is this plant really so special or have we just not given other plants the same attention? I suspect the answer is not a simple one, but if you had some ideas, I love to hear them. Be well.

[jackkennard]

Can tea increase or balance the ph level that could bring down the inflammation response?
Are there any studies on tea & inflammation?

[havencat]

very nice o cover this topic, i never heard it from westerners