Insulin and Glucagon | Physiology | Biology | FuseSchool

Insulin and Glucagon | Physiology | Biology | FuseSchool

In this lesson, you will learn about how your blood glucose level is regulated (or controlled) by two important hormones – insulin and glucagon, via a negative feedback system.

When you consume a meal that is high in carbohydrates, such as rice, pasta, and bread, this will cause your blood glucose level to increase. Carbohydrates are essentially long chains of repeating glucose monomer units, much like beads on a necklace.

During digestion, this is broken apart into glucose, which absorbed into our bloodstream. This increased blood glucose level causes a gland known as the pancreas to secrete a hormone called insulin. Remember that a gland secretes hormones which act on specific target organs.

In this case, the target organ is your liver, which is stimulated to convert glucose to glycogen.
Glycogen is basically long, multi-branched chains of glucose monomers, stored in liver and muscle cells. Insulin also causes your body cells to uptake (or take in) glucose. So this decreases your blood glucose level back to its optimal state.

When this system is faulty, this leads to a medical condition known as diabetes – if you want to learn more about diabetes, this will be addressed in another video. The same response also occurs when you consume foods and drinks high in sugar such as sweets, cakes, and fizzy drinks.

When your blood glucose level drops, such as when you are hungry, the pancreas secretes a hormone called glucagon. Like insulin, the target organ for glucagon is also the liver, though it stimulates the opposite process – the breakdown of glycogen into glucose. This increases your blood glucose level back to its optimal state.

To review, insulin and glucagon are two hormones released by the pancreas, which act on the liver to regulate our blood glucose level.

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[nasseralmansoori]

In short, when sugar (glucose) is too high in your blood, the pancreas sends out insulin that tells the liver to store the glucose as glycogen. When sugar (glucose) is too low in your blood, the pancreas send out glucagon that tells the liver convert glycogen to glucose to raise your blood sugar back to normal.

[drpeppermnt]

I had to rewatch this a few times to get it. Please talk a bit slower and explain more thoroughly in future videos. Love this channel it is really helping me learn.☺📚

[jamieallen]

cant focus with that sound in the background, plus a bit too quick.

[TheMcCheeseGang]

epic

who else is watching this because of a homework task

[zeinana]

This made everything so much easier OMG. 🤣 thank you so much and you kept it short but in a way detailed and you were fast so I could replay it over and over without worrying about time ugh yessss😤💃💃💃

[nettiepetty]

Love showing your videos to my students! Concepts are broken down nice and simply, and the drawings/animations are really basic. I also like that the videos are short.
I have to say that the sound is sometimes a bit too soft though and not always great quality.
The contrast of colours isn't always clear or the font lines are not thick enough (particularly the white font) to be seen especially when projected with an overhead projector to a class.

[MTDogg]

I really appreciate the work that you’ve put into this video 👍

[williamrussell]

very succinct, the pacing is perfect also despite other comments.

[joshnoel]

this was really good i unsterstand it very well now!! keep up the good work

[alejandrahinojosa]

Very helpful for me I like the fact that you write it too because I understand more by reading

[learnwithberryafaithfulser]

:) Short but crystal clear. The animation helped alot . Thank u for sharing this . =)

[AyeshaAht]

PLEASE FIX THE AUDIO, AND DO NOT ADD MUSIC. Other than that, good job in explaining

[melissandlovu]

Yes it is too fast.Slow down in the next videos

[bzybqxq]

I have type 1 diabetes, I know all about this! :)

[michael]

Enjoyed the video. Nice background music too. Thanks

[jayemmgee]

1:49 it sounds like “glycagon” rather than “glycogen”

[pearljameric]

Why does the pancreas use 2 different hormones to do the same job? Thanks!

[TheLestad]

Insulin get the glucose into the cell for energy or store it. Glucagon releases when insulin and glucose is low to extract stored energy. Like glycogen and fat to raise glucose to burn it. But for the cell to burn it doesn't need insulin again to put it into cell or it the glucose goes into the cell without insulin?

[Mengjoanne]

Glucagon = lipolysis? Fasting is the key. Insulin is the safe to fat stores and glucagon is they key to access it. Do I have it right?

[nihelsworld]

Aren’t muscle cells and fat cells a target too for glucagon and insulin.