Can Low Estrogen Make You Tired? Let's find out

Being tired all the time can be challenging, but if you understand how estrogen affects your energy level, you can do something about it.

This is something we talk about a lot in my Hormone Support Group, which is FREE to join:

So, does estrogen cause tiredness?

Yes, it can. But first, you need to rule out other hormone imbalances. You’ll need to get a blood test to check. If your thyroid and adrenal hormone production are fine, it may be your sex hormones to blame. Particularly if your estrogen is low. That’s because estrogen plays a key role in energy production. Unfortunately, blood is a poor way to determine if your estrogen is too low for you though. That’s because every woman is different and what’s low for one woman may be perfect for another. No one ever gets their hormones checked when they’re in their prime and feeling great. So your doctor does not know your hormone baseline. It becomes a guessing game. And tiredness is a vague sign of low estrogen production.

But low estrogen definitely contributes to your tiredness. Ask any menopausal woman. And she’ll probably tell you she doesn’t have the same amount of energy she did when she was still having periods. If you’re going to understand how low estrogen affects your energy level, you need to know how your body makes energy.

Energy is produced from glucose. And glucose cannot get into your cells without insulin. Estrogen plays a vital role in keeping your insulin receptors healthy. Receptors are the little doorways that let your hormones into your cells. Insulin escorts glucose to your cells. Then it acts like a key in the insulin receptor opening up a gateway to allow glucose into your cells. Then the mitochondria in your cells produce energy from the glucose. While thyroid hormone, T3, stimulates mitochondrial activity, it’s estrogen’s job to help insulin get glucose into your cells. Without glucose, you can’t make enough energy. And Estrogen helps upregulates your insulin receptors so glucose can get into your cells. Without adequate estrogen, you can’t make enough energy and you’re tired.


Even if you’re menopausal you can help make the most of your adrenal estrogen production by supporting your hypothalamus. Of course, you can also take hormone replacement therapy but be sure you’re getting enough progesterone to counterbalance estrogen.

Now if you’re struggling with fatigue, please consider supporting your hypothalamus. You’ll learn more about how in our Hormone Reboot Training – where you’ll also learn about how to safely use bioidentical estradiol to increase your mitochondrial energy production so you won’t be so tired.

✔️ Join our Free Hormone Reboot Training:

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This video is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual. Through my videos, blog posts, website information, I give suggestions for you and your doctor to research and provide general information for educational purposes only.

The information provided in this video or site, or through linkages to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call consultation or the advice of your physician or other healthcare provider. Genesis Health Products and Deborah Maragopoulos FNP are not liable or responsible for any advice, course of treatment, diagnosis or any other information, services or product you obtain through this video or site.

[bellaroccisano]

My doctor put me on Estalis patches 50/250 . I felt good at first but 2 months later and all i want to do is sleep.

[carolineiserhoff]

What is milk thistle isn’t magnesium I would like to know please thank you

[SS-dplt]

I am on hrt for a diff issue but I was told progesterone doesn’t matter u just need it for uterine protection. 10 days out of the month. I don’t believe this is right. Don’t I need it to be balanced or for more ?

[svetlanayordanova]

Can you please advice what needs to be the ratio of progesterone to estrogen levels? I am in menopause and take bioidentical HRT with estrogen and progesterone but feel that my progesterone levels are still lower than the estrogen which makes me estrogen dominant. Any advice on how much bigger progesterone levels need to be compared to estrogen will be very helpful. Thank you