Myths & Misconceptions of Insulin Resistance – Ben Bikman – #CoSci

Dr. Ben Bikman, a specialist in bioenergetics and insulin's role in metabolic disorders, presents a comprehensive talk on insulin resistance. He highlights the rising prevalence of insulin resistance and its impact on various chronic diseases. Bikman stresses the importance of precise terminology and understanding of insulin resistance, differentiating between its pathological and physiological forms. Pathological insulin resistance, often linked to chronic diseases, is caused by factors like chronic stress, inflammation, and hyperinsulinemia. Physiological insulin resistance occurs naturally during periods of growth, such as puberty and pregnancy. Bikman also discusses misconceptions about carbohydrate-restricted diets, explaining that while such diets do not cause insulin resistance, they can affect glucose tolerance tests. He emphasizes the need for proper insulin measurement in clinical settings and the role of metabolic flexibility in health.

0:00 - Introduction to Dr. Ben Bikman
0:14 - Opening Remarks and Gratitude
1:13 - Importance of Democratizing Science
2:01 - Common Myths and Misconceptions about Insulin Resistance
2:35 - Prevalence of Metabolic Unhealthiness in Adults
3:19 - Historical Contributions to Metabolism Understanding
4:02 - Pathological Insulin Resistance and Chronic Diseases
5:13 - Pathological vs. Physiological Insulin Resistance
6:13 - Defining Insulin Resistance
7:59 - Insulin's Role and Impact on Glucose
9:51 - The Vicious Cycle of Insulin Resistance
11:01 - Insulin Resistance without Hyperinsulinemia
12:00 - Causes of Insulin Resistance
14:26 - Fat Cells and Insulin Resistance
16:10 - Stress Hormones and Insulin Resistance
18:24 - Inflammation and Insulin Resistance
20:47 - Hyperinsulinemia and Insulin Resistance
22:10 - Physiological Insulin Resistance and Growth
24:19 - Puberty and Insulin Resistance
27:19 - Pregnancy and Insulin Resistance
29:04 - Hormones from the Placenta
30:17 - Carbohydrate-Restricted Diets and Insulin Resistance
32:02 - Insulin Production Changes and Glucose Tolerance Tests
36:02 - Metabolic Flexibility
38:13 - Reverse Metabolic Flexibility
40:18 - Managing Glucose Tolerance Tests on Low Carb Diets
42:37 - Randle Cycle and Metabolic Inflexibility
45:00 - Questions and Answers Session

[northyland]

I have type 2 diabetes. I went low carb, then keto. I skip breakfast. I stopped insulin and never took other meds. My overnight fasting glucose is 95. After meals I hit 122 If i don't exercise, about 89 if I do, which is most of the time. If I fast for 2 or 3 days my BG goes as low as 60.

[dindop]

Ben should've been given more time! Can't stop listening to this guy...

[andrewstrakele]

The man, the myth, the legend, on the cutting edge of Human Metabolism Reseach! 👍👍👍

[BeefNEggs]

Bikman is enjoyable and very informative and easy to listen to. One of the best of the regulars.

[M.Sforza]

This man is a gift to us with metabolic challenges. Thank you Sir!

[MaddogCapt]

I'm sure there is a reason Dr. Bikman doesn't have his own YT channel, but he never fails to dazzle when I find him hosted on Youtube.

[mmarkandaya]

Fantastic lecture! Dr. Bikman takes such complex subjects and explains them so well that even lay people can understand him.

[getter_done]

Always enjoy listening to Dr Ben Bikman! 👏👏👏

[dilettanter]

19:16 about diesel exhaust causing insulin resistance and increased fat was really shocking - does it mediate these effects through inflammation.

[mikeward]

I really enjoy hearing Ben talk even when I've heard before. In this particular talk, notice the integration of contributions from both sides of the brain: the LHS providing a description of the biological models, the RHS speaking to the LHS to remind about the reality of the moment (being a professor, not losing the audiance, leaving time for ...).

[louisacapell]

This happened to me, i did my glucose test after a year of very low carb . 20 and under grams.
I did not know i needed to eat carbs to acclimate my pancreas before the test. .
My Blood sugar was ASTRONOMICAL .
ive since had to convince them im NOT having a diabetic pregnancy by testing 4× a day.
Glucose #s in 60s -90s . Perfect.

[christineellengalbraith]

Bald redhead v Knuckleheads
Excellent content and delivery - you bossed it Ben!

[mikeyfazed]

I wonder who the "knuckle heads" Dr Bikman means at 16:20 are... He seems like such a nice guy, never seen him get so worked up!!

[kriscook]

Dr. Ben - you are the GOAT! God has gifted you to teach. Thank you for all of your talks and teachings. This one is one of my favorites. Bravo! 👏 👏 👏

[fiddlerJohn]

6:52 "insulin is unique among its class of hormones because it is capable of affecting every single cell of the body and that is rare among a lot of hormones and there are so many different types and so many different families but insulin stands apart because every single cell of the body from brain cells to bone cells from lung cells to liver cells has insulin receptors ."
19:18 "Diesel exhaust is capable of forcing 'Adipocyte Hypertrophy' even in totally independent of any calorie signal. Eat the same amount of food the animals get a little scrawnier, but their fat cells get fatter."

[huffhouseart]

Just subscribed, been believing all you've advised, snd feel better than i have for many years thanks.

[quisge]

"Reverse Metabolic Flexibility" appears to be the same phenomenon that Dr. Robert Cywes refers to as "Insulin Suppression". Thank you for including this in the talk!

[pmfith]

I disagree with your last part… I’ve been on a very strict ketogenic diet for the last seven years – absolutely no cheating…carbs always below 20 – and my fasting insulin is rarely below 10. If you do a HOMA-IR calculation on me it shows that I am insulin resistant (2.7). This has frustrated me to no end.

[rosnodj]

The lack of a first phase insulin response with a ketogenic diet is so interesting!

[celebratinglifewithmuthu]

Excellent session. Learned a lot. Love your graphics