Sepsis: Systemic inflammatory response syndrome (SIRS) to multiple organ dysfunction syndrome (MODS)

Created by Ian Mannarino.

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[katie]

Thanks for this information. I'm an RN and it's crazy how you can be taught this so many times and forget to apply it in a clinical setting. My pt was very lethargic and his HR was 140. Did an ECG and he was in sinus rhythm. I didn't know what was causing his change in condition but I spoke with an ICU nurse who looked at his bloodwork and realized his WBCs had been trending down. His last bloodwork was taken 3 days prior. She told me to call the doctor and order new bloodwork because he had chemo 1 week before and he bet that he was septic. Turns out his WBCs were 1, 500 and neutrophils were 0.1. I should have known to look at his WBC count as it is part of SIRS! Great learning opportunity for me.

[globalko]

I had Sepsis 2 years ago, I was so close not going to ER since I thought it only was a cold or something similar. Turned out I had severe sepsis, if I had not had went I would be dead. When I came there my fever elevated to above 40 c, my oxygen was at 70% and I was puking. Scary stuff. Turned out that I had an abscess in my liver.

[nathanhall]

Great vid! I do think it is important to point out that in the sepsis stage, you could probably change it from “Confirmed” infection, to “suspected” infection, just due to the fact that a key in managing sepsis is how early on it is treated with broad spectrum antibiotics. I would say that starting broad spectrum antibiotics before you get any cultures back is probably the best way to go, and then narrowing ABX treatment based on culture results. The government actually has criterion of beginning to treat sepsis within 3 hours of the patient first having information put into the medical record. These reasons are why I would suggest changing it from confirmed to suspected. Nobody will fault you for giving a small amount of broad spectrum antibiotics if it turns out that that there was no infection associated with the SIRS criteria.

[rosemarymckeever]

I had severe Sepsis in 2019 & died at 119*F with Tachycardia. Sometimes Hospitals seem clueless. Thank you for telling me what my Dr’s in PA wouldn’t.

[Cnightz]

Wow, I was in the ICU with Covid19 viral sepsis. Everything in this video is how I progressed while I the hospital with the same 30ml per kl infusions and it didn't touch my HR, Idk if I got MODS but I sure had organ dysfunction of the heart, lungs, kidneys, gi tract and liver.

[stoverma]

this was the BEST explain i've found! you put it in terms easy to understand AND remember!

[Amy-yvry]

This was really well explained. I had sepsis but it was caught early, before organ dysfunction, septicaemia or shock. Some people and doctors don't understand because they don't know the difference between sepsis, septic shock, septicaemia and SIRS. 😕

[neffyiffy]

This is super helpful ! The way this is drawn and organized and displayed/explained is exactly how I learn best, this is a wonderful teacher! Thank you and please continue to post more of these educational videos for us nursing or healthcare/med students!

[aleeyahsadventure]

Thank you fro this video! It heps me a lot for my upcoming exam.

[maneshat]

Thank you so much love how clearly you have explain

[longassride]

I have always been confused about this spectrum. Thanks a lot for clarifying this

[cjware]

Im just trying to keep my mind off him, he was a firefighter, EMT, Truck Driver, Construction Worker and many, many other things. He grew up with adopted parents and his father died when he was 14.. and hes been a quadriplegic for almost my whole life... Since I was about 6 and hes always.. Always been positive.. Not one day have I heard him complain.. He was a big independent survivalist type guy, and he kept being that as much as he could.. He has always been sharp and smart.. Last night he called for me and was asking me the same thing over and over, eventually I did it, and just got him a comfortable as possible.. So I went back to bed.. When I woke up the Aid that comes into help was already here and waiting on another Nurse to look at him and decide weather we need to call 911.. Well as soon as I took a look at him 100% I knew we did, he had snot coming down his nose, and couldn't even notice I was there.. He was completely incoherent and calling for his long passed mother.. I immediately got him to the Hospital and here we are.. He was able to say "Love you" after I said it to him, and he responded to one of his oldest friends when he showed up, but since last night he hasn't said anything, and hes not lucid at all.. He apparently has "sepsis" which is a blood infection..I cant stand the thought of me not being there with him, Ive been there since last night.. I needed to leave to grab things and like I mentioned, I want more then anything to be there for him, but its grueling seeing him like this.. He hates it.. I know it. Hell Who wouldn't.

[mrsdee]

I had all this 2 yrs ago and many other things i was dieing my family was told i only had about many 2 hours left to live but theu saved me i still dont no how i got it i am very lucky to be alive my left arm side and leg doesnt work right anymore and i had to give up work because of it but thank god to my family who saved if you think anyone has it call 911 or in the UK 999 it could save someone life

[tfylhk]

Very informative and excellent presentation

[lucerohernandez]

Will u remake the video with the sepsis 3 guideline?

[peachesh]

I was so confused on sepsis vs septic shock thanks to this vid I understand now 🤗

[DermNerd]

No mention of the patient demographic either: the malady is most common among seasoned individuals, infants, and pregnant women. Also pretty sure there's a second scoring system not covered here.

[snamuwo]

Great and succinct presentation. Highly appreciated. Do you have one on management of Sepsis?

[devasianjavarakattu]

Thank you sir, learned so much from you so far, you are amazing! Keep the good work.

[darlenescott]

I got septic shock the end of this March, my second time getting septic shock in 2 years.