Sepsis and Septic Shock

An review of the definitions, presentation, and management of sepsis and septic shock, including fluid and pressor recommendations.

Useful additional resources:

[StrongMed]

Since this video was posted, there was a credible claim made that the data supporting high dose vitamin C in sepsis had been fabricated, however, an investigation by CHEST found no evidence of fabrication. Nevertheless, subsequent RCTs that have looked at vitamin C in sepsis have found no benefit. I do not personally advocate for using vitamin C in sepsis.

[kabom]

I had Septic Shock due to Pneumonia and respiratory distress (I had to be intubated for 3 days and nights) which led to the loss of my kidney transplant and almost my life. I now am on HemoDialysis and have weakened lungs. This was about 2 years before Covid-19 came about. The docs kept me on my immunosuppressants to keep my antibodies low for my next kidney transplant but I have so much scar tissue it will probably be my last and I am not even 50 yet.

[kultuurimees]

Dr. Strong, you're the man! Wish you had videos about every main topic from each speciality, but for working at the hospital, these videos really help organize the work process by giving a clear structure to the things we're just "used to doing".

[alhaah]

Thank you for in-depth explanation about sepsis and what to do for it. I appreciate that.

[jaquelinemanuel]

Thank you Dr. Strong. You are one of the best lecturers I've seen on YouTube.

[ahmetc]

What a brief, yet a detailed way of expression. I sincerely congratulate you.

[sunving]

Thank you Dr Strong. This is my second time watching this lecture. It is great.

[crit-ic]

Beautiful overview! Great work, dr. Strong!

[namridbo]

Hello from New Delhi, i work in ER and this video help me and strengthen my knowledge

[jally]

I'm a surgery resident and find your videos very helpful n amazing. I look forward to get more n more updated videos

[sunving]

Thank you Dr Strong, wonderful lecture and to the point. Definitely a must for intern .

[liasosa]

Well presented, pitch perfect lecture! Thank you Dr Strong for all you do, much appreciated.

[Kashif]

Excellent video including both SIRS and SOFA.. Sincere thanks Dr Strong..

[pulse]

Very understandable and clear and concise lecture. Awesome .

[everydaydissociation]

Excellent video, some of the best medical content out there, much appreciated Dr Strong 💪🏼

[mariociencia]

Thank you for sharing your immense knowledge through very clear and objective classes. Particularly I loved to know that lactate in sepsis could be the result of intrinsic beta-agonists. These beta-agonists would be adrenaline? I think the relation between sepsis and lactate deserves its own video!

[sothernsweetie]

My baby sisyer just passed away from sepsis on December 19th, 2023😢😢...4 days later her son who was 29 passed away from lunĝ cancer! Very tuff stuff...😢...then my father in law passed away January 7th 2024! Crazy sad hard days!

[ZeyadYam]

your channel is a gold mine of information ... thx a lot !!

[s.e.wagger]

I was told I had a "septic shower". I didn't know I had pneumonia in 2 areas of my right lung. I started shivering, couldn't get warm. Then started violently shaking. Mouth went totally dry. Shaking too badly to hold onto a phone to call an ambulance. Kept dropping a cup when I tried to drink water. When I was able to get some water down, I immediately vomited it back up. Felt myself starting to get light-headed so I laid on the floor in the "coma" position. Slowly lost consciousness or fell asleep (not sure which). When I came to, 40 minutes had passed from initial shivering to waking up on the floor. No longer vomiting or shaking but still felt nauseous. I thought something had poisoned me. Went to a doctor the next day and had x-rays on chest. He told me I had pneumonia and it caused me to have a septic shower by "smashing" the infection in my lung into my blood stream. Treated me with 2 courses of different antibiotics. It was terrifying, as I thought I was about to "step into eternity".

[gRaz]

Great information as always! Thank you for your work