How To Stop & Reverse Aging with Dr. David Sinclair

#DavidSinclair #JoeRogan #AntiAging #Aging #NMN #Fasting #Diet #2021 #Metformin #Supplements #ReprogramYourBody #ResetAge #ResetYourBiologicalAge #BiologicalAge #AgingProcess #ReverseAging #StayYoung #FountainOfYouth

David A. Sinclair, Ph.D. is an entrepreneur, tenured professor at Harvard Medical School, and world leader in aging research. He has published over 160 scientific papers, is a co-inventor on over 50 patents, and has co-founded 12 biotechnology companies in the areas of aging, vaccines, diabetes, fertility, cancer, and biodefense. David is the author of the bestselling book Lifespan: Why We Age―and Why We Don't Have To. He serves as co-chief editor of the scientific journal Aging, works with national defense agencies, and works with NASA. He has received 35 honors including being one of Australia's leading scientists under 45, TIME magazine’s list of the “100 most influential people in the world” and many more.

SHOW NOTES & TIMESTAMPS
01:44 Introduction and David Sinclair Bio
02:29 Interview Begins
03:00 Is Aging Natural?
04:01 Resetting the Biological Clock
06:39 Aging at the Cellular Level
10:58 What is the difference between the genome of the epigenome and how do they interact in the body?
14:29 Lifespan controlled by Genetics (20%) and Epigenetics (80%)
15:18 How does Epigenetic Reprogramming take place?
18:54 How much variance can there be between your biological age and your chronological age?
19:57 Activities that reduce caused mortality
21:19 How Epigenetic Reprogramming Occurs and Ways to Support It
24:02 What are some of the strategies for making your sirtuins more effective?
27:19 Why fasting is so effective
30:09 How does cold exposure work to reverse or slow the aging process?
33:46 Importance of external stressors to keep your sirtuins proactive
35:29 Modern comforts making us more prone to aging
36:49 The process of aging reversal
40:27 Future of Age Reversing Science
42:40 The What and Why of the Supplements David takes to Mitigate Aging Effects
48:58 What can you start doing now?

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[biohackerindonesia]

Hey David, you are a blessing to our generation, keep doing good work, may Godbless you

[jaked]

David Sinclair a genius. Not dumb people talking nonsense. Read his book! It’s that very good.

[TheBiffo]

If u read Lifespan by David Sinclair u will have a lot more understanding how it all works, , I want to live Healthier & Longer, which is the key healthier longer

[vladiS]

David Sinclair is amazing! He is like one of the Avengers! I have read his work and listen his talks!!! I love his progressive thinking and his determination!!! He is one of the persons I would love to meet in person!!

[falconone]

If we can dramatically speed up our aging with stress and the wrong foods for example then there must be a way to also slow it down.

[bryanmarty]

Fantastic interview. Well done to both the interviewer and interviewee!

[valeriehopebennett]

GREAT THANKS IT WAS DELIGHTFUL AND EDUCATIONAL

[jeffhogueison]

I have took real Resveratrol for 15 years along with Metformin and HIIT exercises. Amazing Dr. Sinclair looks as young as me..I am 55 :) maybe it does work. I am active and feel like 40

[harrywhite]

Which came first the genome or the epi-genome? The original cell had to be created by the mother as a sort of kick start to running the DNA through that first cell but after that the epi-genome must also be self replicating. So the instructions for how to replicate an epi-genome must be contained in the DNA along with the instructions to build you.

[rustybolts]

Most usefully informative video I've found in about a year. The last one was from some guy named Dr. David Sinclair of Harvard U...!

[mahriathompson]

I could get it better if there were pictures to see what he’s talking about. Also it would be good to see you both in person! Your way here is just like listening to the radio or a CD.

[annarazzu]

Thanks so much !...
From Noth Sardinia !

[snelson]

In Canada (Victoria, BC) I cannot get Resveratrol in the powder form, only in a capsule (Natural Factors). It's derived from Japanese Knotweed and the powder inside the capsule is dark brown, not white as you suggest it should be. It's difficult to buy products on-line, as they often get stopped at the border. Any suggestions?

[evasz]

I can see slowing aging however I can't imagine that we would be able to reverse it. It would be really nice. In practical terms, with reverse aging would we be able to reverse osteoporosis or would be able to reverse menopause or would we be able to get our original hair colour back?

[RotPhalkun]

Moringa is your solution to aging & sickness. Molicule in the plant amazes you. (There are people live longer before your research. Every person live short or longer on this earth is base on their purpose. We all have a purpose in life).

[nonzenz]

Siim Land has got good books on cold exposure / sauna and the science behind it. Metabolic Autophagy

[sleepsmartsmashstress]

Is this inner clock digital one or the old fashioned with two or three hands Dr. Sinclair?

[oliviamiller]

Life expectancy has jumped, mainly because infant survival rates are much higher than they once were. Poor hygiene and nutrition, less advanced medicine and more communicable diseases meant that newborns in Ancient Greece and Rome had a much lower chance of surviving their first few years. But by combatting age-linked illnesses, we can extend our life and live until a hundred and fifty. I too have spent a lot of time confused with the push back to ending death and extending human life. As more people see it as a true option, I hope they’ll move past the fear of death and see it’s all really quite possible! It’s through Dr. Sinclair's podcasts I learned about Vitruvin Anti-Aging Supplements and ever since I am taking this NMN supplement, it radically changed my life.

[aaliyahlee]

Everything appears to speed up in our perceptions as we get older. Aging is biological decline. Your body needs all the help it can get. I take NMN by Vitruvin Nutrition every morning with a protein drink and some Greek yogurt. It has radically changed everything. All sorts of problems have mostly disappeared. I have lots of energy. My vision is better, aches and pain are almost gone, and my mental clarity is like pretty well. At 75, that’s not shabby.

[hgos]

Hi David,
Just wondering which supplement you’d recommend to take first. Is it resveratrol or NAD? Which brands of each us best?