The Hallmarks of Aging: Altered Intercellular Communication | LifeXtenShow

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Cells in your body don’t exist as isolated units; they talk to each other, and correct intercellular communication is essential for your health. Unfortunately, intercellular communication goes south as you get older, and that’s one of the reasons we wind up getting a bunch of nasty diseases later in life. Can we fix that? Possibly!

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Music:

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Sources:

The Hallmarks of Aging
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217.

Parabiosis

Villeda, S. A., Luo, J., Mosher, K. I., Zou, B., Britschgi, M., Bieri, G., ... & Lucin, K. M. (2011). The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature, 477(7362), 90.

Rebo, J., Mehdipour, M., Gathwala, R., Causey, K., Liu, Y., Conboy, M. J., & Conboy, I. M. (2016). A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. Nature communications, 7, 13363.

Alkahest clinical trials

Alkahest

Rejuvenation Roadmap
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#Inflammation #Aging #Inflammaging #Parabiosis #MolecularBiology #Biology #LifeExtension

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Amazing video. Thank you. Shared on Twitter!

rebelScience
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Thank you so much for taking the time to prepare this content, very informative and on point!

eternalambition
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I have read many papers in this foeld and I undrestood that your video is a good summary of all! Thanks

saraassar
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Inflammaging...catchy! I love it almost as much as I love Nicola's shirt :D Great video as always!

Danath
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they also found I believe that dilution of old blood with just plasma also works to reduce inflammation, But there is no money in that so it will be interesting to see where that goes. Has anyone else hear of that study?

richardnunziata
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awesome video. you also remind me of Charlie Kelly from always sunny lol

jakelaforge
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Damn this is far more interesting than A level biology

imperialgamer
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Please use a less distracting background! While it's fancy looking, it does make reading more difficult.