Peripheral Nerve regeneration with nerve conduits

In this video, I will talk about a practical way of using stem cells and scaffolds for inducing regeneration in our nervous system. We will learn about natural peripheral nerve regeneration and how we can make a nerve conduit as a scaffold for guiding axonal regeneration.
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References:
1. Onode, Ema, et al. "Bioabsorbable nerve conduits three-dimensionally coated with human induced pluripotent stem cell-derived neural stem/progenitor cells promote peripheral nerve regeneration in rats." Scientific Reports 11.1 (2021): 1-13.

2. Doblado, Laura Rodríguez, Cristina Martínez-Ramos, and Manuel Monleón Pradas. "Biomaterials for neural tissue engineering." Frontiers in Nanotechnology 3 (2021): 643507.

3. Uemura, Takuya, et al. "A tissue-engineered bioabsorbable nerve conduit created by three-dimensional culture of induced pluripotent stem cell-derived neurospheres." Bio-Medical Materials and Engineering 21.5-6 (2011): 333-339.

Attributions:

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The music tracks in this video is composed by:

1. Luminescence by @HolarMusic

2. Rounding by @SavfkMusic

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Timestamps:
00:00 Nervous system
00:37 Regeneration in nervous system
03:00 Autologous nerve graft
03:28 Nerve conduit
03:46 Nerve conduit and iPSC for regeneration
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#regeneration #biomaterials #biomaterials

[saumyask]

one of the best videos I came across on the internet that is explaining the nerve conduits in such a simple and understandable manner. The creativity of the video is amazing.

[DespondentHorse]

Excellent video
Hope there is some breakthrough soon
Pudendal nerve is in dire need

[KhalidAli-pqgu]

Amazing video. I wonder if this will be helpful for people who had permanent damage from long-term nerve compression such as Carpal Tunnel Syndrome or Cubital Tunnel Syndrome. This seems like a good concept to apply to these cases as well, since these nerves are effectively dead, and can also potentially alleviate atrophied muscles if it works.

[dwdwone]

If peripheral nerves regenerate, how come neuropathy persists?

[basmanm]

What is he pla and pcl?
Is it polymers
Well come back doctor

[dudejoyce]

Has anything ever come from this? Are people getting help ?