Sleeping: Adenosine and Melatonin

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Dr. David Seiden, Medical Director of the Pembroke Pines Sleep Center with Baptist Health South Florida, explains adenosine is the breakdown product or byproduct of cellular metabolism. "By the end of the day, adenosine levels are quite high, and as our adenosine levels rise, it tends to make us sleepier. That's very interesting, because caffeine acts by blocking adenosine levels, therefore it keeps us awake".

He also says we have a circadian rhythm, it is genetically programmed and it is mediated by melatonin. When there is a lot of light during the day, signals are sent to the retina, and then to the middle of the brain. Those signals are to tell the pineal gland to suppress melatonin, but at night, with less stimulation of the retina, melatonin is then produced.
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How exactly does adenosine differ from melatonin? Why do we have 2 chemicals that help us sleep?

arunkenta
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No importa quién seas: Si lees esto‚ te quiero mucho‚ eres un ser súper valioso‚ hermoso y eres capaz de hacer todo lo que te propongas ❤️

SomosLaNuevaEra
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Its too short and i feel like he didnt exactly answer the question (didnt have enough time?)
the question was that if there is a change in our sleeping routines(eg sleeping in day and working at night) does this change have any affect on the person? How?

justbb
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why are there night owls if there is less light that could tell the brain to sleep

classicalbuzz
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so what if one doesnt have a pineal gland? such as myself. It was removed during a brain tumor operation. How does one explain how i still sleep?

ryantammul