These Are The Symptoms Of Mast Cell Activation Syndrome

Are you having a bunch of varied symptoms, maybe chronic health problems, itchy skin, asthma, digestive problems, headaches, maybe it could be mast cell activation syndrome.
So in this video, we're going to look at the symptoms of mast cell activation syndrome.
In this video we're going to look at the symptoms of mast cell activation syndrome. What different systems of the body, like cardiovascular, digestive, those symptoms tend to come up in.

And we'll also look at some of the underlying themes with this problem called mast cell activation. In this video we're going to look at the symptoms of mast cell activation. Mast cell activation syndrome is a condition in which mast cells, which are a specific type of white blood cell, are overactive, and they're producing and releasing high amounts of their granules, which are histamine and other immune activating chemicals.
00:00 Introduction to Mast Cell Activation Syndrome
01:24 Understanding the Symptoms of Mast Cell Activation Syndrome
02:45 Exploring the Systems Affected by Mast Cell Activation Syndrome
05:11 Triggers and Sensitivities in Mast Cell Activation Syndrome
05:52 Diagnosis and Conclusion
The histamine and increased immune activity cause a wide range of symptoms touching on many different systems of the body. Oftentimes people come in with a laundry list of symptoms, not realizing that they could all be connected through this unifying syndrome called mast cell activation syndrome.

It can be tricky to spot though, because the symptoms of mast cell activation can vary widely from person to person as well. And it's important to take a careful look at each of the symptoms because they may not be related, but they definitely could be. so let's look at some of those symptoms.

So some of the symptoms and corresponding systems that could be occurring for mast cell activation syndrome. I'll just list some of the systems involved and then we'll go back and touch on the symptoms within that system. So the systems could be things like your skin, digestive tract, cardiovascular system, mental and emotional, respiratory system, urinary system, and even joint musculoskeletal system. So in the skin, you're oftentimes gonna have, obviously, itchy skin and problems like rashes, hives, and this can vary from one person to another. The degree of which these symptoms may show.

Remember those mast cells are producing a lot of histamine and histamine's a very itchy, burny type of symptom. Digestive symptoms, similar thing. It's gonna have a lot of those burning discomfort type of symptoms, but it could also just be pure abdominal pain. There obviously could be constipation or diarrhea, irritable bowel type things. Bloated, nausea, vomiting, but it could also be acid reflux burning in the mouth and throat. Et cetera. Oftentimes people with this syndrome, two are gonna be more prone to sinus infections and upper respiratory tract infections. Headaches and migraines independent of sinusitis and upper respiratory issues are also gonna be common. Because they are oftentimes triggered by histamine cardiovascular system.
Yes, there could be blood pressure fluctuations. Something known as POTS syndrome also has a lot of overlap with mast cell activation syndrome. So there could be dizziness and lightheadedness as blood pressure drops as a result of the histamine activity. Heart palpitations and chest pain can also be common.

And part of the overall histamine response, mental and emotional things, yes, there can be a lot of fatigue in the legs, brain fog with that, memory problems, and difficulty concentrating, but the mood can change. So it's often times they'll be activated or stimulated and anxious at certain times, and then also be totally out of energy at other times.

And it's caused by the immune system going through ups and downs with that. When the histamine levels are high, people can be anxious because that histamine is very stimulating to the nervous system. Joint pain and muscle pain can also be common with mast cell activation syndrome.

Of course we mentioned upper respiratory tract issues, but you could also have like asthma and things like that going on. And in general, these people are going to be more sensitive to medications, foods, and supplements, because those mast cells are often over-triggered and oversensitive, and it has to do with something going on in the digestive system, but there could also be more immune regulatory problems going on as well.

[OnlyMe-uknh]

I have spent my whole life from childhood trying to get a doctor, any doctor to take me seriously concerning my symptoms, but I always was written off as a hypochondriac, drug seeking, having mental health issues and just being over weight. I turned 51 last year and now spend a lot time in a wheelchair. About 2 years ago I got sick of doctors telling me it’s in my head and started to research. Ends up I have have EDS. I was formerly diagnosed last year. Now the secondary diagnosis’s are coming in. I also have MCAS, POTS, osteoarthritis, osteoporosis, my discs are degenerating, I now also have scoliosis and the beginnings of Ankylosing Spondylitis. All I ever wanted from a doctor is to be taken seriously.

[ChronicExcessiveManliness]

Beneficial overview. Based on experience and other people's testimony, probably 98% of all doctors have little to no (and I mean no, none) knowledge of this. As in they think patients are making up the symptoms and the term. So, it's nearly impossible for most people to get diagnosed at this point in time, (though it's improving slowly) patients are ignored and told to see...a shrink. So yes, videos raising awareness...help.

[ThePrincessdi]

this is me…migraines POTS unexplained heart racing or palpitations, skin rashes, struggle w temp changes, pure exhaustion 24/7, IBS, dizziness on the daily, chronic sinus issues, joint pain starting in my 20s, extreme water retention, swollen lips eyes hands so on and so on no one knows why I’m so sick!!!! Wow I am blown away by this as I have an answer now and can bring this up to local doctor!

[josephcernansky]

WOW!!! "over-sensitization to drugs, THAT EXPLAINS a ton of things!!

[j.a.]

You’re the first doctor that’s explained symptoms aside from the predictable allergic symptoms. Thank you!

[pinklady]

I was diagnosed with MCAS/POTS 3 years ago. You hit on a lot of what I deal with.

[Amy-ofgw]

YOUGoodness! I am forwarding this video to my doctor who told me a low histamine diet was not a medical issue, and the doctor who wrote a cookbook was just selling BS! I am changing doctors, I do not have time or energy to EDUCATE the person controlling MY health! Honestly with a high school education, it is way above my pay grade to discern all the information on MCAS, hEDS, Food, Chemical and Environmental Allergies, difficulty with EMF, 5G, Fibromyalgia, and let’s not forget psychology issues OCD, ADHD, Depression and cPTSD! It is SO easy for doctors to just mark the CRAZY box, collect their fee and move down the 15 minute healthcare conveyer belt.

[gagehitchner]

I got diagnosed with POTS back in september and ankylosing spondylitis in august I did a mast cell workup as well (still don’t have any word of what the results are for that) and I thought it was all a scam because after 2 years of fighting the drs for a diagnosis other than anxiety I got these two conditions that I never heard of just seemed off to me but here i am now wheelchair bound at 26 years old no income was hospitalized and put in a nursing home for almost a month and still going through hell and back because “not enough specialists know enough on how to treat it” I get pinpoint rashes, skin writing, sometimes hives and itching, rapid weight loss, fatigue, tachycardia, blood pressure spikes and drops, hypoglycemia, arthritis, weakness, digestion issues, intense pressure headaches that ive never felt in my life its nothing like a migrane or standard headache, body temperate doesnt regulate correctly, dry mouth eyes and nose as well as taste and smell issues, acne, easy brusing, and the list goes on and on but every blood test and mri or ct scan always comes back normal so they dont considerate it life threatening and send me home everytime

[myrna]

Yes, another video for a deeper dive into this subject. Please and thank you.👍🏾😀

[calmrestored]

This is so helpful. I had chronic “utis” that strangely had no bacteria on testing. Thankfully I had a thorough urologist who discovered it was actually a problem with mast cell activation. The relief to finally have a cause for the pain was incredible.

[debramilam.]

Please do another video….what can help with this syndrome?

[tinapetersen]

I’ve been dealing with this for 28 years! Doctors didn’t know what to do with me. It’s so good having it recognized now.

[DawnMarieisme]

Really interesting video. I have a call booked with my GP soon to ask for assessment of MCAS/histamine intolerance. Just hoping he is receptive to this discussion although he has been amazing/open minded with past requests.

[harrylew]

Thank you! For the first time in 40 years, my many symptoms are starting to make sense. BTW, how about a follow-up video on treatments, if any.

[Hvshi-tomi]

Wow, you just summed up my daughter. She’s been diagnosed with POTS, JIA, Asthma, Eczema, Gerd, Dermographia, all kinds of digestive issues, has IBS symptoms (not diagnosed) and her dr told us mass cell issues, but not diagnosed MCAD. And possible EDS. Now she’s having trouble with her heart. Because her blood pressure goes so extremely high to extremely low. She is also having trouble with multiple utis, kidney issues. The list goes on .
And she just turned 20. Unfortunately we no longer have health insurance. Nor can we afford to buy it outright on our own. So she just suffers . It’s hard as a Mom to feel so helpless . All I want to do is help my child. Especially with her being so sick .
Life is hard sometimes.

[patafilo]

Skin, digestive, burn sensation in front and back of my body. I was diagnosed two weeks ago

[sophiabright]

Thanks for laying this out so clearly. Helpful indeed. We are NOT crazy and we do go through better/worse cycles. Extremely crazymaking.

[deemarie]

Gee this was short and sweet. I liked the breakdown. Helped me understand my symptoms more clearly

[leslietascoff]

Also bladder discomfort - feels like UTI - similar to interstitial cystitis.

[memsat]

gOOD VIDEO DR. TERANELLA, not too many practitioners or even patients are aware of this syndtome. Before I was diagnosed, I would spontaneouly have a panic like attack usually almost resulting in near anaphylaxis. I had to carry an epi pen and I always have Benadryl on hand. It has greatly diminished as I have aged.