Next generation CRISPR screens based on single-cell transcriptomics | Tilmann Buerckstuemmer

We hosted Dr. Tilmann Buerckstuemmer, CSO of Aelian Biotechnology, who’ll be talking to us about leveraging two transformative technologies - CRISPR screening and single cell transcriptomics - to enable genetic screening for complex phenotypes.

During this webinar Dr. Buerckstuemmer will discuss:

- how Aelian Biotechnology is using CROP-seq to expand beyond more simplistic screening read-outs.

- how this screening approach can be used to map known signalling pathways and assess the impact of candidate regulators on transcriptional outcomes.

- the feasibility of using both unbiased and targeted single-cell RNA sequencing and how to compare these approaches side-by-side.

- the importance of Oligo Pool uniformity to ensure screening success and how the quality of Twist Oligo Pools uniquely enables these types of studies.