Glutamine: Health Benefits & Muscle Recovery- Thomas DeLauer

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What Does Glutamine Do? It is known to play a protective role in our immune and digestive systems - it is used medically to help those undergoing chemotherapy with both digestive problems and immune system function as well as for those diagnosed with bowel surgery to improve recovery. Glutamine is formed by our muscles and released into the bloodstream to be delivered where it is needed throughout the body. Glutamine provides nitrogen and carbon to cells throughout the body.
Glutamine and the Immune Response: When our bodies have gone through something stressful, such as surgery or a traumatic episode, nitrogen is needed to keep organs functioning and to heal wounds. About ⅓ of this nitrogen is delivered via glutamine. While under healthy, normal conditions our bodies are able to create enough glutamine, when we experience lots of stress our bodies could use more glutamine via supplementation. This is because our bodies have been found to have lower blood and muscle glutamine levels after major stress.
-This is likely due to the supply exceeding the demand
This lowered glutamine plasma concentration is thought to be tied to the hampered immune system functions following such stressors.
It was found that supplementation of glutamine following bone marrow transplantation was tied to lower infections and shorter hospital stays. (2)
This positive impact on the immune system is through the effect of glutamine on lymphocyte proliferation and cytokine production.
-Lymphocytes are a type of white blood cell that produce antibodies that attack invading cells and those of the body that have been taken over by the virus/cancer
-Cytokines are molecules that aid cellular communication when immune responses occur, leading to cell movement towards injured sites such as infection and inflammation
Glutamine and Healthy Gut Functioning: When you experience digestion problems such as bloating and pain, this is caused by inflammation. Just as glutamine aids in healing after a traumatic event, your body responds similarly to an inflamed gut, as inflammation is an immune response. When your gut is inflamed, the intestinal permeability increases. Large particles are able to pass through to the blood, causing your immune system to respond and attack food similar to how it attacks pathogens. The gut is not only responsible for digestion and nutrient absorption, but also protects us from invading pathogens. Glutamine has been linked to decreased intestinal permeability through its ability to strengthen the walls of the gut.
Dosage: The average dietary consumption of glutamine per day is 6g. Supplements are available as L-glutamine in tablets, capsules or powder. How much to take depends on the symptoms that you are presenting, with the suggested daily supplementation ranging from 2 g to 20 g. Consult your doctor before taking large amounts of glutamine. If you have an ulcer or other health concern they can help guide you as to the best amount to take. If you are worried about your immune system or gut health, for example if you have experienced a recent trauma or are training for a marathon, supplement with 2 g to 5 g per day.
References:
1. Glutamine
2. Glutamine and the immune system
3. Lymphocytes
4. What are cytokines?
5. Glutamine: effect on the immune system, protein balance and intestinal functions
6. Glutamine and whey protein...Crohn’s Disease
7. Dosing and efficacy of glutamine supplementation
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My dad left when I was seven and I started taking glutamine felt much better about it

legendarypasos
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Gave my wife Glutamine when she was going through chemo and it helped a lot. She had a large wound at the time and it actually healed while getting chemo which is somewhat unheard of. The doctors were legitimately shocked. It also prevented mouth sores and kept her digestive tract feeling good.

Anyone going through chemo or recovering from surgery should 100% be taking glutamine.

RobustMustache
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I swear taking Glutamine after my surgery helped me heal SO much faster! My doctor was shocked at my first appt after surgery. I’m still healing but am so far ahead of others with the same surgery date online. I truly believe in this supplement now!

MrsStevenBrown
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As a nurse we even gave it to people in cancer treatment and it works. I even feel it when I take it. Recovery speeds up greatly. It also keeps my stomach in check. I tell anyone with stomach ace to take it.

RONNYMORRISMUSIC
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Glutamine is a great Immune booster, got sick in Powerlifting training cycles, with glutamine i can go trough alot of training without getting sick

SplashFireFilms
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I started taking glutamine awhile back and around the same time began to try get back up to my normal weight of 190 lbs. I weigh 175. I have been eating like crazy and I wondered why I could not gain any weight at all. I suspected that maybe it was the glutamine so I stopped taking it. I have started gaining the weight back!! If anyone is interested in weight control, take glutamine.

rerere
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See that's why I love this channel - I just had a hip replacement and this was great info for me! Should I take a Glutamine supplement to help aid in my recovery? Thanks Thomas!

user
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You have taught me so much and helped me improve my health so much. Thank you!

Johncetrone
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An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized from scratch by the organism fast enough to supply its demand, and must therefore come from the diet.

How'd you get that one wrong?

alejandrogn
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Great explanation! Solidified my decision to start supplementing with glutamine!

jonahbettman
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Thank you. And you need to say what the proper dosage is needed and when to take it?

jimbro.
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As always really insightful. One point which I am confused about though, is the point about giving glutamine to cancer patients during treatment. Other medical professionals talk about how cancer cells thrive on glucose and glutamine. They suggest reducing glutamine not only by avoiding glutamine supplementation but also reducing the glutamine consumed from food by performing intermittent fasting. You can see my confusion, as both theories contradict one another. Great video, I'm just confused on that point.

outtheresomewhere
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Thank you so much for sharing this knowledge to us. Can you please make a video on L-arginine and L-carnitine ?

Tankzim.z
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I was wondering why my gut healed in the last days and now I know

sohaibkhamlichi
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Excellent information! You always learn a lot from Thomas DeLauer.

higherresolution
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thanks for taking your time to video this just please take sometime to asnwer some people questions which are very good, if u made this video put it online for the public at least take care of your viewers a llittle.

manoleo
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I would only take glutamine supplements after a fast, a really hard workout, or severe injury, some acute trauma. For chronic stress, removing the stressor is much better.

Maatdrummer
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So informative, from a bodybuilding background, glutamine is superb. It definitely allows me to eat/digest food more

jayroberts
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Its almost impossible to get all the micro nutrients from the food we eat, even the most healthy foods, so supplementation is a must!!

ishwarip
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Just started watching your channel and I love it !!! Thank you 😃

mvov