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The primary shield: role of our microbes in heath and diseases
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The primary shield: role of our microbes in heath and diseases
Air date: Wednesday, April 26, 2017, 3:00:00 PM
Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:44:18
Description: NIH Director’s Wednesday Afternoon Lecture Series
The microbiota plays a fundamental role in the induction, education and function of the host immune system. In return, the host immune system has evolved multiple means by which to maintain its symbiotic relationship with the microbiota. The maintenance of this dialogue allows the induction of protective responses to pathogens and the utilization of regulatory pathways involved in the sustained tolerance to innocuous antigens. The ability of microbes to set the immunological tone of tissues, both locally and systemically, requires tonic sensing of microbes and complex feedback loops between innate and adaptive components of the immune system. Dr. Belkaid will discuss some of the dominant mediators of these interactions and discuss emerging themes associated with our current understanding of the immunological dialogue between the host and its microbiota in health and diseases.
Dr. Belkaid work explores the field of immune regulation and has defined fundamental mechanisms that regulate tissue homeostasis and host immune responses. Her work uncovered key roles for the commensal microbiota and dietary factors in the maintenance of tissue immunity and protection to pathogens.
Author: Yasmine Belkaid, Ph.D., Director, Microbiome Program, Chief of the Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, NIH
Air date: Wednesday, April 26, 2017, 3:00:00 PM
Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:44:18
Description: NIH Director’s Wednesday Afternoon Lecture Series
The microbiota plays a fundamental role in the induction, education and function of the host immune system. In return, the host immune system has evolved multiple means by which to maintain its symbiotic relationship with the microbiota. The maintenance of this dialogue allows the induction of protective responses to pathogens and the utilization of regulatory pathways involved in the sustained tolerance to innocuous antigens. The ability of microbes to set the immunological tone of tissues, both locally and systemically, requires tonic sensing of microbes and complex feedback loops between innate and adaptive components of the immune system. Dr. Belkaid will discuss some of the dominant mediators of these interactions and discuss emerging themes associated with our current understanding of the immunological dialogue between the host and its microbiota in health and diseases.
Dr. Belkaid work explores the field of immune regulation and has defined fundamental mechanisms that regulate tissue homeostasis and host immune responses. Her work uncovered key roles for the commensal microbiota and dietary factors in the maintenance of tissue immunity and protection to pathogens.
Author: Yasmine Belkaid, Ph.D., Director, Microbiome Program, Chief of the Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, NIH
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