Vaccines and the Immune Response: How Vaccines Work

Vaccines and the Immune Response: How Vaccines Work
This animation provides an overview of vaccines and the immune response, and how influenza vaccines work. Influenza vaccines are able to trigger an immune response by mimicking viral infection. They are usually manufactured using inactivated or killed virus particles taken from various circulating influenza strains.

[illunisam]

Some people may find that reading the information is easier for them.
Influenza vaccines work by using inactivated viral particles containing hemagglutinin h and neuraminidase NA(sub-Varian particles) to trigger an immune response by injecting it into the muscle. Immune cells such as macrophages, T and B cells will break the hemagglutinin into small components by ingesting it(macrophage phagocytosis). On the surface of the macrophage, the hemagglutinin antibody and the major histocompatibility complex(MHC t-cells) will appear. Now the MHC t-cells can bind to antigens associated with the MHC. T-cells become either cytotoxic t-cells, suppressor t-cells, or helper t-cells. Helper t-cells have hemagglutinin receptors, can produce antibody creation, and help with memory b-cell activation. B-cells can ingest hemagglutinin without MHC. After ingestion, it then presents the hemagglutinin along with the MHC on its surface. If an active B expressing the antigen MHC and T-cells interact, the T-cell secretes lymphokines, which will differentiate the b-cell into either a memory b-cell or a plasma cell. Plasma cells make hemagglutinin antibodies specific to the strain in the vaccine. Memory b-cells help fight against future infections by activating the immune response.
Aerosol droplets containing live influenza droplets try to infect the nasopharyngeal epithelial layer of the body. The antibodies either block or diminish the severity of the virus.

[sirwalterj]

I feel like a 5 year old walking into an adult conversation

[ClickBaitFishin]

This 3 and half minute video feels like I've been sitting in class for a whole day

[leeamraa]

I'll keep this video on my "Watch-Later" list until I go get my PhD in medicine! ... I'll be back!

[ElvinJones]

For everyone saying that thought this was really complicated, consider this:

A virus (in most cases) has no life or DNA of its own. It has to replicate by using a living thing’s DNA (in the nucleus of its cells) as a host. However the virus does have its own RNA that uses that DNA for its own purposes. The vaccine uses a modified form of the RNA that your cells/DNA mark and use in a way that get all of the cells in your body to clock the virus as a threat and smash it at every stage. It an awesome video but I can see how people might get lost in the details. Hope that helps.

[michelleandreacruz]

Went here to get an idea how vaccine works. Ended up even more confused 😞

[modguy]

As a computer science student, I did not understand a thing

[OhLatte]

I’m surprised I actually understand this 💀 yall, for everyone who’s confused I recommend watching cells at work. It helped me a lot and it’s fun to watch :)

[shahabmamaghani]

It is the best concise animation explaining interactions involved in vaccination

[Chloe-moxb]

Thank you so much! I had previously watched another video which I found too vague and general. This video was clear and informative, and I appreciate the scientific detail.

[emvytsu]

i am a father to 5 and my kids arent vaccinated
edit:4
edit:2 kids

[kolticc]

Pretty simple its like training ur cells to recognize the enemy if needed

[terryfilms]

Can someone please translate this to the English language? Thank you in advance.

[chaidude]

2:32 antibodies produce hemagglutinin antibodies 1:38 t helper cells functions

[jannatwani]

wooh man my brain cells went on hibernation after watching this video :)

[SoulStorm]

I am glad that I am not the only one too stupid to understand this video

[Raine]

Goddamn. I need a course in micro biology just to understand this

[sanga]

I’ve watched this to help me better understand but feels like your brain been eaten alive🤣🤣🤣🤣

[Faeryboots]

So if reactive lymphocytes showed in my blood work 10 days post vaccine, does it mean my immune response is working?

[karolinagrunwald]

I'm assuming MHC1 is for endogenous and MHC2 for exo? Or other way around 🤔