PCR (Polymerase Chain Reaction)

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Join The Amoeba Sisters as they explain the biotechnology technique PCR. This video goes into the basics of how PCR works as well as two examples of its potential use.

Table of Contents:
00:00 Intro
1:34 How does PCR work?
4:31 Why use PCR?
5:10 rRT-PCR testing for SARS-CoV-2 (virus that causes COVID-19)
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Factual References (and excellent for learning more detail about this topic):

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FURTHER READING SUGGESTIONS:

On RT-PCR for SARS-CoV-2:

On Fluorescent Probes in PCR:

What about limitations or disadvantages of PCR?

What about more uses for PCR (as well as more info about Nobel Prize):
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Our Resources:

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MUSIC:
Our intro music designed and performed by Jeremiah Cheshire.

COMMUNITY:
We take pride in our AWESOME community, and we welcome feedback and discussion. However, please remember that this is an education channel. See YouTube's community guidelines and how YouTube handles comments that are reported by the community. We also reserve the right to remove comments.

TRANSLATIONS:

Thank you so much to our amazing translators!
Turkish subtitles by Kardelen Ünalleylioğlu
Hindi subtitles by Alisha Aggarwal

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We like to pin comments for clarifications or corrections. We have one part in the video where we had the cDNA spelled out and there is a misspelling - when the cDNA is spelled out, it should be spelled *complementary* DNA. Thanks again for the comment about this- we were able to correct!

AmoebaSisters
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I'm 40, just started grad school, and taking a genetics class....you have no idea how useful your videos are. Thank you!

rociobustamante
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I already graduated from college, but I’m still here watching these videos

royalrod_
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As a senior undergraduate in Biology, I treasure your videos. You girls are amazing! Saved me lots of time when I needed to review a subject for my Biochemistry or Molecular Biology lessons 😊

ProfEdDiaz
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These videos are helpful even after my physiology degree! They are working as great little refreshers while I study for the MCAT. Sometimes my mind feels too overwhelmed by the kaplan books and all of the heavy information I've been rehashing, so I come and watch these to give myself something to study thats quick, clear, and understandable without a head ache!

nubbosaur
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Studying for a Biochemistry exam as part of my physician assistant program and came across this video! So thankful for your time to share your understanding. Will continue to use your page when studying in the future!! Thank you!

jenniferdonatella
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Thx so much!! I literally have a huge bio practise exam for feedback this afternoon

potat
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First of all, I just wanted to say that I really admire your video; the animation, the teaching style and how simple you make and present the concept is why you are my favorite channel.. You make the concepts that I really didn't understand easy and make me truly enjoy biology. I am sure that you are working super hard on your videos and in the same time you are a full time teacher, so it must be tiring . But i think a great way to improve your channel would maybe, in a another channel or even this one to make remake videos or make videos with all the details possible with the same animation and teaching style so that we can truly understand everything ( i am not saying that i am dissatisfied with your videos, i think they are near perfect) because when i try to watch YouTube videos that explain more in detail, I have difficulty understand them . I just think that with your brilliant way of teaching and the amazing animation style that help us understand biology, you could make understand all your viewers even with the most difficult and detailed material. I know that it would take a large amount of time and I would understand if just didn't have the time but if its possible for you to make longer videos with more details, i think that it would really improve your channel and help the biology students to have a more grasp understand of biology.

mounirzouhari
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You guys are the only reason I'm passing biology class at age 36, hahaha. Thank you for what you do!

thisgalisonfyr
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I’ve already done PCR in a lab but the way you present it is so well that I watch it anyways 😂 great video!

chicken
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I´m doing my master degree and learning about the PCR and your videos are really useful! Thank you to combine the science with the creativity!!

brendalujanoalegria
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I had an exam with a question about PCR today and then this came out. I loved it anyway.

camilacordero
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Ever since my biology teacher introduced you, I have been LOVEING your biology videos it makes me laugh at the drawings and lets me focus on the facts!!

kelving
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I m studying Electrical Engineering and came across this concept while studying Biology for Engineers(academic sub).Enjoyed your video and also understood concepts in easy way.Thanks for it!

Tanmay
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Love it! This is my go-to source when outreaching and correcting the record about PCR for the general public. Thank you. There is so much disinformation out there we need more simple-to-understand videos like these. Keep up the amazing work.

DrReginaldFinleySr
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I just decided to choose biochemistry as my thesis topic, and I am soo glad to find these videos! I love them! It helps me with my study a lot! Thank you soo much!!

dominika
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Kay. To start off I don't usually comment on videos but I had to for this one. You guys are awesome like I'm a vivid yt watcher and I don't think I have come across anything that had me this engaged. Kudos to ya!! Keep being awesome you

shreyaaaaaa
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You do not know how much this videos mean to me. Without ur channel, I would never have been able to pass biology!

ilsem
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Amoeba Sisters I want to tell you. You are the lifesaver, every times I am going to have an exam your clips always work, it makes my life easier I doesn’t need to read a book and just look at your clips. It is amazing. Please continue this cute video forever.

ธนธัชลีพิทักษ์รัตน์
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I had a science test today and your videos really helped me
pass! Thank you for doing these videos!

emmiezzz