AGEs: The Surprising Link Between our Diet and Aging [Advanced Glycation End Products]

The second video in my Spring Forward Your Health series is here! In this lecture I'm diving into the world of advanced glycation end products (AGEs), hidden toxins lurking in our food and cooking methods. I'll uncover how these compounds accelerate aging and increase the risk of chronic diseases. Join me as I explore the surprising link between our diet, aging, and disease. After watching you will understand what ages are AGEs and simple changes you can make to your cooking and eating habits to protect your health. Don't let your food age you prematurely!

In the coming months there will be a few lectures on various topics. Make sure you’re subscribed to be notified when they are released! I apologize for the audio issues in this lecture, we have it all sorted out for future lectures.

Chapters
0:00 Introduction to Advanced Glycation End Products
2:44 What Are Advanced Glycation End Products?
12:38 The Damage From AGEs
17:46 How are AGEs Formed?
26:50 Inhibitors of AGEs
27:52 What foods have AGEs?
31:54 The effects of consuming AGEs
34:13 Measuring AGEs
38:42 How Cooking affects AGEs
56:53 The effects of Fasting
59:41 Receptors of AGEs
1:04:54 Supplements and Take-Home Points
1:08:11 Q&A - 1. What are your thoughts on Honey?
1:09:18 Q&A - 2. Can you please explain What Benfotiamine is?
1:11:32 Q&A - 3. Why is sourdough bread better for you?
1:12:18 Q&A - 4. Does Ghee Cause Cancer?
1:13:12 Q&A - 5. Is fasting unhealthy for Younger people?
1:14:47 Q&A - 6. Is there a way to tell if I am prematurely aging?
1:16:29 Q&A - 7. Can you lower your calcium score?
1:18:58 Q&A - 8. Where do you buy turmeric?

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About Dr. Pradip Jamnadas, MD, MBBS, FACC, FSCAI, FCCP, FACP
The founder and Chief Medical Officer of Cardiovascular Interventions, P.A. in Orlando Florida where, since 1990, he has been repeatedly recognized in local publications as a Top Doctor performing thousands of interventional procedures in hospital and out patient settings. As a consultant cardiologist with a large diversified inpatient and outpatient practice he is noted for his passions for teaching and illuminating prevention for cardiovascular disease . He is also a clinical assistant professor of medicine at The Florida State University and University of Central Florida.

[jm_]

For those that don't know. This is one of the most brilliant doctors in the world. He saved my life in the cath lab last year. Being a practitioner myself and in cardiology for 25 years, I can assure you that his skill level is impossibly high. I'd not be typing this without him. Please listen to his teachings. He is not wrong. Thank you Dr. J.

[DavorMaksimovic]

🎯 Key points for quick navigation:

Advanced glycation end products (AGEs) are harmful compounds formed when sugars attach to proteins, lipids, or nucleic acids, causing damage to various bodily functions.
AGEs contribute to inflammation, oxidative stress, and premature aging, leading to chronic diseases such as diabetes, cardiovascular issues, kidney problems, and neurodegenerative conditions.
AGEs can be generated not only from high blood sugar levels (diabetes) but also from other factors like high fructose intake, lipid peroxidation, alcohol consumption, and smoking.
Consumption of processed foods, especially those high in sugars and fats, increases AGEs in the body, affecting the microbiome and overall health.
Continuous glucose monitoring is crucial for understanding individual sugar responses and managing AGE formation.
Inhibiting AGE formation can be achieved through lifestyle changes, including dietary modifications, reducing sugar intake, and practicing intermittent fasting.
Certain vitamins and natural compounds like curcumin, alpha lipoic acid, and flavonoids found in vegetables and herbs can help counteract the formation of advanced glycation end products (AGEs) in the body.
AGEs are formed when sugars in food combine with proteins and fats during cooking, especially through processes like reheating, frying, baking, and grilling, leading to tissue damage and various health issues.
Foods high in sugar, processed foods, and animal products are particularly rich in AGEs, with cooking methods like frying and grilling exacerbating AGE formation.
Consuming moist-cooked foods, marinating with lemon or vinegar, and avoiding high-temperature cooking methods can help reduce AGE formation.
Processed meats, fried foods, and high-carb items are among the worst offenders for AGE content, while fruits, vegetables, and moist-cooked proteins tend to have lower levels.
Proper cooking techniques such as poaching, stewing, or steaming can significantly lower AGE levels in food, making them healthier options.
Understanding the formation and impact of AGEs can help individuals make informed dietary choices to mitigate health risks associated with AGE consumption.
53:16: Cook pasta al dente for fewer AGEs; avoid overcooking grains and legumes to minimize AGE formation.
54:26: Opt for raw nuts over roasted ones to reduce AGEs and lipid peroxidation.
55:45: High-fat spreads like cream cheese and mayonnaise are high in AGEs; choose ghee or refined coconut oil instead for lower oxidation.
56:26: Avoid dry heat-prepared snacks like crackers and cookies to minimize AGE intake.
57:08: Fasting reduces glycation and slows aging; intermittent fasting can improve health markers and longevity.
59:28: Lower AGE intake improves collagen health and reduces skin aging.
01:02:16: Inhaling AGEs from cooking oils can harm lung health; avoid inhaling smoke from high-temperature cooking.
01:06:45: Three golden rules to reduce AGEs: avoid vegetable seed oils, alcohol, and processed foods; opt for fresh, unprocessed ingredients.
01:07:55: Honey, especially heated, is high in fructose and AGEs; limit consumption for better metabolic health.
01:10:32: Methylated B12 complex supplements can aid in AGE reduction and improve genetic expression.
01:13:08: Intermittent fasting can improve health markers and reduce inflammation; protein intake is crucial during fasting to support detoxification and ketogenesis.
01:15:12: Calcium score and epigenetic aging clock offer insights into arterial and physiological age; anti-inflammatory lifestyle and diet are key for arterial health.

[lakshmipathykm]

I am a nuclear molecular physician, I am enlightened by this presentation on AGEs, great knowledge, wise doctor..God bless him..lots of respect regards and love❤ from chennai India

[shirleymurphy]

Sure wish when I was younger I knew this. But its never too late . By changing my diet and fasting I have seen good changes. I am 74. Thank you for this information.

[queeneenaa]

finally new video by our beloved doctor

[carlrusso]

He saved my life in 1998 after my cardiologist gave me a death sentence. He has guided my path since then as a doctor, a mentor, and a friend. Carl R., Orlando

[heinzh]

From a 54 year old quadruple bypass patient God bless you for your compassion and information 🙏

[arpigracetarkhanian]

I flew from LA to see him 🙏 I will continue to see him 🙏♥️🙏 the man is full of wealth of wisdom 🙏 blessings 🙏

[JonathanPopZAR]

Can't get enough of your vids, my Sunday fix, Doc you and Jason Fung along with Dr Sten Ekburg.
Please don't stop creating this content

[ShellyHelman]

My husband is under his care now and I know it will change his life forever! Dr. J is a rockstar!!! What a blessing to be able to have him in our lives now. Can’t wait to see my husband truly smile for the first time in such a long time and will be pain free.

[neusapedro]

Thanks to you I stopped consuming added sugar (I dont miss it at all), eating only whole foods and fasting. My health improved very quickly ❤️ found you 5 months ago and you saved my life. 15kg gone so far.
Thank you.

Salut from Azores Islands, Portugal

[lieweheksie]

I used to know THAT they are bad, now I at last know WHY. Thanks for sharing with members of the public

[dennisilyaich]

Hands down the most profound lecture I have ever heard. After looking up this Doctors credentials, and listening to his passion on prevention of CAD and many other diseases, Ive subscribed. He literally saves lives as a cardiologist. Also, he inspires and educates people on how food effects the body. One can think that they are eating healthy, managing their lipids, sugars, but have no idea that grilling our food or cooking in high temp is contributing to disease. Discovering AGEs is revolutionary.

[mariamoreira]

I'm addicted to his videos! Everything he says makes so much sense!

[bbldb]

I’m a survivor of my first 70 years. Today’s video ties so much of my missing information. I’m 77 now and have recovered so well, now I have more of the story. Thanks Doctor.

[Nyt]

This guy is brilliant. Thankfully, I already knew a lot about fasting before I discovered him, but I learned so much more advanced stuff through his lectures.
Listen to this guy. He is telling the truth and genuinely cares about your health.

[MPuzzlesRecords]

You are a genius. Its a pleasure to come across this video. So full of knowledge. After I lost two of my most beloved family members, and saw my mother lost a Kidney, I began studying cancer. I got obsessed. Carbohydrates, sugar, glucose, fructose, enemies by themselves, but combined? ☠️ Then you throw dehydration and a sedentary life (lack of oxigenation, not moving enough, not exercising), and an acidic environment that comes from insulin resistance, not having homeostasis, etc. You begin to understand aging, diseases, cancer. Free radicals, oxidative stress, Glycation, are crucial terms, that need to be fully understood, to live a better, healthier live. I think that’s all we want. Peace, be free of diseases, and enjoy this life.
Greetings from Puerto Rico 🙏🏻

[katrinadavis]

Not only is this doctor very knowledgeable beyond measure he truly cares about educating others and getting them well and keeping them well. I’m impressed by the compassion he has for others. Most doctors are not like him.

[wiseguy]

This the only person across the Social media spectrum I have the notifications on for

[tadeth]

I have always regarded him as a world class since I first watched him some years ago. Thanks for confirming my notion.