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DNA Damage and Repair | Why is it important?

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This is an introduction video for DNA Damage and Repair and talks about why is it important?
Here’s a list of types of DNA damage and their repair mechanisms:
Base Damage
Repair Mechanism: Base Excision Repair (BER)
Single-Strand Breaks (SSBs)
Repair Mechanism: Single-Strand Break Repair (SSBR)
Double-Strand Breaks (DSBs)
Repair Mechanism: Non-Homologous End Joining (NHEJ), Homologous Recombination (HR)
Pyrimidine Dimers (e.g., Thymine dimers)
Repair Mechanism: Nucleotide Excision Repair (NER)
Mismatch Errors (e.g., base pairing errors)
Repair Mechanism: Mismatch Repair (MMR)
Crosslinks (e.g., DNA–DNA, DNA–protein)
Repair Mechanism: Interstrand Crosslink Repair (ICL)
Oxidative Damage
Repair Mechanism: Base Excision Repair (BER), Direct Repair
Alkylation Damage
Repair Mechanism: Direct Repair, Base Excision Repair (BER)
Chromosomal Translocations
Repair Mechanism: Homologous Recombination (HR), Non-Homologous End Joining (NHEJ)
These are broad categories, and each type of damage can have specific pathways or proteins involved. #DNAdamage #csirnet #csirlifesciences #biotechnology
Here’s a list of types of DNA damage and their repair mechanisms:
Base Damage
Repair Mechanism: Base Excision Repair (BER)
Single-Strand Breaks (SSBs)
Repair Mechanism: Single-Strand Break Repair (SSBR)
Double-Strand Breaks (DSBs)
Repair Mechanism: Non-Homologous End Joining (NHEJ), Homologous Recombination (HR)
Pyrimidine Dimers (e.g., Thymine dimers)
Repair Mechanism: Nucleotide Excision Repair (NER)
Mismatch Errors (e.g., base pairing errors)
Repair Mechanism: Mismatch Repair (MMR)
Crosslinks (e.g., DNA–DNA, DNA–protein)
Repair Mechanism: Interstrand Crosslink Repair (ICL)
Oxidative Damage
Repair Mechanism: Base Excision Repair (BER), Direct Repair
Alkylation Damage
Repair Mechanism: Direct Repair, Base Excision Repair (BER)
Chromosomal Translocations
Repair Mechanism: Homologous Recombination (HR), Non-Homologous End Joining (NHEJ)
These are broad categories, and each type of damage can have specific pathways or proteins involved. #DNAdamage #csirnet #csirlifesciences #biotechnology
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