Mechanism of DNA Replication (Basic)

Knowing the structure of DNA, scientists speculated and then proved that DNA is the template for copying the genetic code. See how information in DNA is copied to make new DNA molecules.
TRANSCRIPT: Using computer animation based on molecular research, we are now able to see how DNA is actually copied in living cells. You are looking at an assembly line of amazing miniature biochemical machines that are pulling apart the DNA double helix and cranking out a copy of each strand. The DNA to be copied enters the production line from bottom left. The whirling blue molecular machine is called helicase. It spins the DNA as fast as a jet engine as it unwinds the double helix into two strands. One strand is copied continuously and can be seen spooling off to the right. Things are not so simple for the other strand because it must be copied backwards. It is drawn out repeatedly in loops, and copied one section at a time. The end result is two new DNA molecules.

[DNALearningCenter]

Visit us in Cold Spring Harbor, Brooklyn, or Sleepy Hollow!

[PhazonOmega]

What, replication looks like THAT? Why isn't this in any textbooks! I'm a bio major and had NO IDEA it looked ANYTHING close to this amazing and ordered! Thank you so much for the video!

[diavlosuelto]

I find this compelling and beautiful. The speed at which this happens is astounding, something like 50 nucleotides per second. If only my telomeres were longer to see where else we may go.

[chemnuke]

I can't even explain how awesome this is.

[TheGreatSeraphim]

This utterly blows my mind. I finally have an answer to what actually divides and replicates dna.

I found it very hard to comprihend that DNA just pulled itself appart at will.

[gogarten_lab]

If I am not mistaken, Drew Berry created this animation. Why is he not credited here?

[macvillx]

This video part of a talk given by Drew Berry: Animations of unseeable biology, at TED. I think, like most of the people that have commented here, that this is awesome, more than awesome. For me, too, this has been absolutely mindblowing and educational. At last I can, sort of, understand what goes on at DNA level. Thanks for the upload.

[RochdChati]

is the side that must be copied backwards more prone to errors ? I would imagine just based on the fact it has an extra step in it, it would be more prone to it

[natashaholder]

Oh DNA Learning Center, you make living so much easier whilst studying.

[marumisu]

Is this animation 1:1 accuracy? Is it an assumption? How close to what’s actually happening is this because this is fairly incredible. Patterns of mechanical engineering being discovered on a small scale. It makes me wonder why there aren’t plants that do something similar to this. Like why is it only on a microscopic scale that this pattern is possible naturally?

[muhammadaminkhan]

Is this the video 6.4 of which you mentioned in your lecture yhomad

[TDXdz]

In the words of Salman Khan, if THIS does not blow your mind, then you have no emotion.

[while_coyote]

The end result is not *just* two DNA molecules!  It's one DNA molecule with almost no transcription errors, and another DNA molecule with far more mutations.  The end result being a remarkably beautiful way to keep old genes and experiment with new ones simultaneously!  EVOLUTION IS AMAZING!!

[Novak]

That's advanced production line. That's ultimate engineering  !!!

[loodLust]

I think it's because it's hard to put moving animations in textbooks, but I may be wrong.

[geirtwo]

How the hell does this little fella know what to do?

[MinecraftXExpert]

this is simple... watch the advanced one! then you will realize how this is basic. it makes sense though. i guess watching it in my 7th grade science class helps!

[ActiveStorage]

funny how they put random mechanical sounds in their. ppl plz dont forget that all these visualizations are very speculative

[romeodaddi]

wonderful, ... i i stucked speachless.... . !!!

miracle of life exposed!.

[leelapleela]

if it is modified as in textbook it will be better