DNA Replication Made Easy

DNA Replication Made Easy

DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. The cell possesses the distinctive property of division, which makes replication of DNA essential.

DNA is made up of a double helix of two complementary strands. During replication, these strands are separated. Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. Cellular proofreading and error-checking mechanisms ensure near perfect fidelity for DNA replication.

In a cell, DNA replication begins at specific locations, or origins of replication, in the genome.[3] Unwinding of DNA at the origin and synthesis of new strands results in replication forks growing bi-directionally from the origin. A number of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DNA polymerase synthesizes the new strands by adding nucleotides that complement each (template) strand. DNA replication occurs during the S-stage of interphase.

DNA replication, like all biological polymerization processes, proceeds in three enzymatically catalyzed and coordinated steps: initiation, elongation and termination.

Replication fork

Many enzymes are involved in the DNA replication fork.
The replication fork is a structure that forms within the nucleus during DNA replication. It is created by helicases, which break the hydrogen bonds holding the two DNA strands together. The resulting structure has two branching "prongs", each one made up of a single strand of DNA. These two strands serve as the template for the leading and lagging strands, which will be created as DNA polymerase matches complementary nucleotides to the templates; the templates may be properly referred to as the leading strand template and the lagging strand template.

[nkcpbry]

Stumbled upon Hidden DNA Potentional on shirlest and it opened up a whole new world for me. The ideas presented are revolutionary, and I’ve seen major changes in my life since then.

[alaska]

Im going to share this with all the doctors I know, because I have never found something as simple and excellent like this! thank you! greetings from a Latin country! :)

[anaisedwards]

Bless you, none of my reading would tell me what "5 prime" or "3 prime" meant and this is so so helpful! Your drawings are so satisfying to watch, and so clear. Thank you!

[annamay]

Thanks for explaining about the 3‘ to 5‘ concept in detail, I haven’t seen that in other videos and it helps me to relate this to other concepts.

[ramshabegum]

Great explanation and animation.
Your voice is very calming.
Keep it up and thank you so much for helping me understand such difficult topic so easily.
Waiting for new videos.

[bry]

My teacher made us watch this so I didn't want to but now that I finished I'm glad I did. The animations really helped me understand what the heck is going on

[pharmian]

How can someone voice is too soothing 🤍

[elinafranklabanova]

Awesome explanation... Just last week my friend suggested me this YouTube channel and I have viewed this video many times... Good for revising

[drakshamharshasree]

No words to express, you are amazing is an small word to say you, , I got an full clarity thank you so much 🙏🙏🙏🙏🙏

[mahamudulhassan]

Please sir we need transcription and translation related lecture,
because our exam is near.

[bhaswatsarma]

The best explanation ever I hv seen about DNA replication

[MikaDobro]

Love your teaching dude. you just made everything simpler.

[TAPTheArtsPeople]

many you tube videos exist, but all confuse us more than elucidating. Thank you for clarity. May be we should also get some still pictures as the video goes on to refer to them in piece meal

[rjayamrsr]

Your video is great . your voice is so calming thank you so much and your teaching really helps me during my exams thank you

[astatamang]

many thanks, slides and animation-outstanding, explanation-outstanding, voice -very calming and enjoyable to listen to. I was wondering if I can get text of your presentation.thank you once again

[diamonddiamond]

Please make more videos on other biology and as well as chemistry. Thank you ❤️❤️❤️❤️

[msabbasi]

Could u please make a video on ATP formation, light and dark reactions of photosynthesis and ABO and Rh blood group systems... will be really thankful

[kirakira]

thanks a lot !!! I just finished my STPM biology paper and one of the essay question is about dna replication. Thanks for easier explanation about this topic which lets me more unstanding about the process of dna replication😆

[leenshammout]

You made it crystal clear thank you so much, Your explanation is good enough even I laughed when you asked for a 100 like, you have 280K subscriber now and you deserve it, keep going

[himanshu]

you have made such an OUTSTANDING VIDEO. Really thankful to your channel. I dont think any appraisal would be able to suffice your hard work & presentation.