DNA Replication in Prokaryotes | Initiation

In this video we have discussed the Initiation part of DNA replication in Prokaryotes where the enzymes and proteins attach to the DAR sequence and initiate the process of unwinding . The unwinding is done by Dna A protein and then other proteins accompany the initiation process.
The Proteins involved in process are :
Dna A protein : ADP and ATP Bound.
Dna B : The Helicase enzyme which breaks the Hydrogen bonds.
Dna C : Helicase Loader.
Dna G : Primase enzyme.

[Emilia-wedc]

Literally the BEST video on this subject. Summarized everything that was in the textbook way more visually. Thank you!!!!

[kathy-leew]

My professor gave us a different approach as to how the dsDNA becomes ssDNA at the 13-mer region. They told us that the ssDNA-binding-domain in the DnaA Protein causes the strand separation and didn’t mention an introduction of topological stress due to the coiling of the DNA around the Protein DnaA.
I find your explanation much more logical. Thank you!

[Rishab]

Wow sir u r an artist who explain it's knowledge in terms of art. Tysm for explaining this topic

[nigelsimbarashe]

i like this, pure accurate dispensing of molecular biology knowledge. Thank you very much Sir

[bilaliyafcjrusson]

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[appikondaReshmika]

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[SONALI_]

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[himanshusharma]

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[ayushijaiswal]

This video is so old but still it is the best for this topic. Excellent👏

[motivationalstudy]

Yes, there are 5 of 9mer sequence in this stage of initiation

[rohanavinashphatak]

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[NaDee-mhpo]

I have a test for this on Thursday. Thank you for making it easier to understand.

[RohitPant]

Great explanation, Hussain but doesn't Ori-c sire in prokaryotes contain 9 nucleotide motifs of 5 repeats & not 4 repeats as you mention here?

[nouriakhan]

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Teach pharmacology as well...😢💔

will be thankful to u 😊...

[shivaniojha]

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[hamihamro]

Finest video on the topic in YouTube ❤️

[Mission-Omega.]

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[AjGaming-vxpc]

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U make every concept very easy

[saikumargsaikumar]

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[ayeshaali]

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جزاك الله